Polytechnisches journal /

Volume 190 ink stamped "Gewerbe-und Handels-Verein"

Képzési és kimeneti követelmények: ajánlás

Az új kétszintű magyar felsőoktatási képzési rendszerben is fontos szerepet játszanak a képzési és kimeneti követelmények. Ezek adják meg az alapot a szakindítások megítéléséhez és az intézményi tantervek kidolgozásához. A cikkben a követelményeket hierarchikus rendszerben látjuk jól megvalósíthatónak: az általános és a képzési ágakhoz tartozó leírásokat követik az intézményi szintű szakleírások. Mindezek lényegi eleme a kimeneti oldalra történő koncentrálás, a kompetenciákra építés. A cikk utolsó részében ajánlásokat fogalmazunk meg a képzési és kimeneti követelmények formai megvalósításához.

Organizational maintenance manual including repair parts and special tools lists : installation kits for alarm, chemical agent, automatic, portable, for truck, 2-1/2 ton, M13 (FSN 6665-479-2718) ... w/power supply for truck, utility, 1/4 ton, M16 (FSN 6665-479-2716).

Includes index.

Different correlation of Sphingosine-1-Phosphate receptor 1 with receptor activator of nuclear factor kappa B ligand and regulatory T cells in rat periapical lesions

Introduction Sphingosine-1-phosphate receptor 1 (S1P1) is crucial for regulation of immunity and bone metabolism. This study aimed to investigate the expression of S1P1 in rat periapical lesions and its relationship with receptor activator of nuclear factor kappa B ligand (RANKL) and regulatory T (Treg) cells. Methods Periapical lesions were induced by pulp exposure in the first lower molars of 55 Wistar rats. Thirty rats were killed on days 0, 7, 14, 21, 28, and 35, and their mandibles were harvested for x-ray imaging, micro–computed tomography scanning, histologic observation, immunohistochemistry, enzyme histochemistry, and double immunofluorescence analysis. The remaining 25 rats were killed on days 0, 14, 21, 28, and 35, and mandibles were harvested for flow cytometry. Results The volume and area of the periapical lesions increased from day 0 to day 21 and then remained comparably stable after day 28. S1P1-positive cells were observed in the inflammatory periapical regions; the number of S1P1-positive cells peaked at day 14 and then decreased from day 21 to day 35. The distribution of S1P1-positive cells was positively correlated with the dynamics of RANKL-positive cells but was negatively correlated with that of Treg cells. Conclusions S1P1 expression was differentially correlated with RANKL and Treg cell infiltration in the periapical lesions and is therefore a contributing factor to the pathogenesis of such lesions.