991 resultados para 203-1243B


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An abstract of title for multiple lots in Peter H. Hamilton’s survey, south of Hunter Street, in the City of Hamilton. The lots involved range from lots 93-203 (non-inclusive). The document is dated November 10, 1865. The entries are dated from 1798 to 1865 and include the grantor, grantee, lands and instrument. The name Geo. S. Papps, Esq. appears centred at the top of the page. The document is signed at the bottom by John H. Greer, Registrar. A note on the reverse side of the document reads “Re Angus Abstract”.

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Using Doppler-free two-photon absorption spectroscopy, we have measured hyperfine splitting constants as well as isotopic level shifts of the 6s^2 np ^2 P_l/2,3/2 states in (n=7-10) in ^203 TI and ^205 TI. Calculations for hyperfine constants and electron density at the nucleus have been performed by the Dirac-Fock method. The experimental results are compared with these calculations as well as with the predictions of the semiempirical theory.

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Marguerite Tolbert (1893-1982) was a Winthrop alumna (class of 1914), club woman, and administrator with the Opportunity School in Columbia, South Carolina. The Marguerite Tolbert Papers consist of correspondence, manuscripts, galley proofs, biographical sketches, newspaper clippings, and other records relating to the publication of the book, South Carolina’s Distinguished Women of Laurens County. Miss Tolbert served as coordinator for the book project. Also included is an unpublished manuscript written by Clara Yarborough concerning the terms of office of seven former South Carolina governors. Miss Yarborough served as secretary under these governors.

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Several studies have linked overexpression of the LIM and SH3 domain protein 1 (LASP1) to progression of breast, colon, liver, and bladder cancer. However, its expression pattern and role in human prostate cancer (PCa) remained largely undefined. Analysis of published microarray data revealed a significant overexpression of LASP1 in PCa metastases compared to parental primary tumors and normal prostate epithelial cells. Subsequent gene-set enrichment analysis comparing LASP1-high and -low PCa identified an association of LASP1 with genes involved in locomotory behavior and chemokine signaling. These bioinformatic predictions were confirmed in vitro as the inducible short hairpin RNA-mediated LASP1 knockdown impaired migration and proliferation in LNCaP prostate cancer cells. By immunohistochemical staining and semi-quantitative image analysis of whole tissue sections we found an enhanced expression of LASP1 in primary PCa and lymph node metastases over benign prostatic hyperplasia. Strong cytosolic and nuclear LASP1 immunoreactivity correlated with PSA progression. Conversely, qRT-PCR analyses for mir-203, which is a known translational suppressor of LASP1 in matched RNA samples revealed an inverse correlation of LASP1 protein and mir-203 expression. Collectively, our results suggest that loss of mir-203 expression and thus uncontrolled LASP1 overexpression might drive progression of PCa.

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Vorbesitzer: N. Brüll

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Zu einem Besuch Stoltzes

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Vorbesitzer: Heinrich Anton Cornill-d'Orville (Exlibris im Vorderdeckel)

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1 Brief von Frederick Pollock an Robert M. MacIver, [1941]; 1 Brief von Max Horkheimer an Lou Eisler, 06.11.1941; 1 Brief von Paul Guggenheim an Frederick Pollock, 20.10.1941; 1 Brief von der Library of Congress (Washington) an Frederick Pollock, 19.10.1941; 1 Brief von S. Lorris an Frederick Pollock, 15.10.1941; 1 Brief von Frederick Pollock an Glidden Buick, 22.09.1941; 1 Brief von Margot von Mendelssohn an das Department of State (Washington), 02.09.1941; 1 Brief von Stephen Duggan an Frederick Pollock, 07.08.1941;

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Vorbesitzer: Michelangelo Gualandi