990 resultados para 194-1193


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In un arco temporale che copre il decennio settanta, ma che si spinge fino ad analizzare anche il dibattito italiano odierno, la presente ricerca ricostruisce i passaggi attraverso i quali l’aborto, da pratica clandestina, è diventato un “fatto” che ha creato e cambiato l’opinione pubblica italiana. Non si tratta di una ricostruzione cronologica pura e semplice, ma quello che si propone è un percorso che procede per temi, utilizzando una particolare chiave di lettura delle fonti giornalistiche e degli atti parlamentari che documentano la costruzione complessiva del discorso. In tale prospettiva, un particolare rilievo assumono alcuni momenti della storia italiana che, nell’arco del decennio, hanno favorito l’immissione di un argomento così complesso, delicato e inusuale come il corpo riproduttivo delle donne sulla scena pubblica, facendone un tema da agenda politica dei partiti. Tra gli eventi più significativi che la ricerca individua certamente il processo a Gigliola Pierobon, avvenuto a Padova nel 1973, di cui si propone una lettura attraverso la chiave interpretativa dell’affaire. Si tratta di una forma di costruzione discorsiva di un “fatto di legge” codificata da Voltaire nel XVIII secolo e ripresa attraverso gli studi dell’antropologa Elisabeth Claverie e del sociologo Luc Boltanski , che applicano in maniera diacronica il concetto di “affaire” a diverse “situazioni di conflitto”, strutturando in tal modo il concetto di “verità contro la legge” . La ricerca è stata condotta utilizzando sia fonti giornalistiche che da diversi punti di vista, hanno fotografato e “tradotto” per l’opinione pubblica il dibattito culturale e politico sul tema dei diritti riproduttivi, sia utilizzando gli atti parlamentari ufficiali , cioè le trascrizioni delle sedute del dibattito alla Camera e al Senato che tra il 1976 e il 1978 hanno creato i presupposti per la nascita della legge 194.

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The European Community has stressed the importance of achieving a common understanding to deal with the environmental noise through community actions of the Member States. This implies the use of harmonized indicators and specific information regarding the values of indicators, the exceedance of limits and the number of people and dwellings exposed to noise. The D.Lgs. 149/2005 in compliance with the European Directive 2002/49/EC defines methodologies, noise indicators and types of outputs required. In this dissertation the work done for the noise mapping of highly trafficked roads of the Province of Bologna will be reported. The study accounts for the environmental noise generated by the road infrastructure outside the urban agglomeration of Bologna. Roads characterized by an annual traffic greater than three millions of vehicles will be considered. The process of data collection and validation will be reported, as long as the implementation of the calculation method in the software and the procedure to create and calibrate the calculation model. Results will be provided as required by the legislation, in forms of maps and tables. Moreover results regarding each road section accounted will be combined to gain a general understanding of the situation of the overall studied area. Although the understanding of the noise levels and the number of people exposed is paramount, it is not sufficient to develop strategies of noise abatement interventions. Thus a further step will be addressed: the creation of priority maps as the basis of action plans for organizing and prioritizing solutions for noise reduction and abatement. Noise reduction measures are reported in a qualitative way in the annex and constitute a preliminary research.

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W5.43(194), a conserved tryptophan residue among G-protein coupled receptors (GPCRs) and cannabinoid receptors (CB), was examined in the present report for its significance in CB2 receptor ligand binding and adenylyl cyclase (AC) activity. Computer modeling postulates that this site in CB2 may be involved in the affinity of WIN55212-2 and SR144528 through aromatic contacts. In the present study, we reported that a CB2 receptor mutant, W5.43(194)Y, which had a tyrosine (Y) substitution for tryptophan (W), retained the binding affinity for CB agonist CP55940, but reduced binding affinity for CB2 agonist WIN55212-2 and inverse agonist SR144528 by 8-fold and 5-fold, respectively; the CB2 W5.43(194)F and W5.43(194)A mutations significantly affect the binding activities of CP55940, WIN55212-2 and SR144528. Furthermore, we found that agonist-mediated inhibition of the forskolin-induced cAMP production was dramatically diminished in the CB2 mutant W5.43(194)Y, whereas W5.43(194)F and W5.43(194)A mutants resulted in complete elimination of downstream signaling, suggesting that W5.43(194) was essential for the full activation of CB2. These results indicate that both aromatic interaction and hydrogen bonding are involved in ligand binding for the residue W5.43(194), and the mutations of this tryptophan site may affect the conformation of the ligand binding pocket and therefore control the active conformation of the wild type CB2 receptor. W5.43(194)Y/F/A mutations also displayed noticeable enhancement of the constitutive activation probably attributed to the receptor conformational changes resulted from the mutations.

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Hypertension is the most prevalent form of cardiovascular disease (CVD) in the world, and is known to increase the risk for developing other diseases. Recently, the American Heart Association introduced a new classification of blood pressure, prehypertension (PHT). The criteria for PHT include a systolic of 120-139 mmHg and/or a diastolic blood pressure of 80-89 mmHg. It has been observed that individuals with PHT have a higher risk of developing hypertension later in life. Therefore, it is important to understand the mechanisms contributing to PHT in order to possibly prevent hypertension. Omega-3 fatty acids found in fish oils have been suggested as a means of lowering blood pressure. However, little is known on the effects of fish oil in PHT humans. Therefore we conducted two studies. In Study 1 we investigated PHT and normotensive (NT) individuals during a mental stress task. Mental stress is known to contribute to the development of hypertension. In Study 2 PHT and NT subjects were placed in an eight week double-blind placebo controlled study in which subjects consumed 9g/day of either fish oil or placebo (olive oil) in addition to their regular diets. Subjects were tested during a resting baseline (seated and supine), 5 minutes of a mental stress task, and 5 minutes of recovery both pre and post supplementation. We measured arterial pressure (AP), heart rate (HR), muscle sympathetic nerve activity (MSNA), and forearm and calf vascular responses. In Study 1 PHT demonstrated augmented AP and blunted vasodilation during mental stress, but MSNA did not change. In Study 2, fish oil did not directly influence blood pressure, MSNA or vascular responses to mental stress. However, it became clear that fish oil had an effect on some but not all subjects (both PHT and NT). Specifically, subjects who experienced a reduced blood pressure response to fish oil also demonstrated a decrease in MSNA and HR during mental stress. Collectively, the investigations in this dissertation had several novel findings. First, PHT individuals demonstrate an augmented pressor and blunted vascular response to mental stress, a response that may be contributing to the development of hypertension. Second, fish oil does not consistently lower resting blood pressure, but the interindividual responses may be related to MSNA. Third, fish oil attenuated the heart rate and MSNA responses and to mental stress in both PHT and NT. In conclusion, we found that there are both similarities and differences in the way PHT and NT individuals respond to mental stress and fish oil.

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An electrodeposition of an iron-manganese alloy was made from the same conditions determined by previous re­search. Various addition agents were experimented with in an attempt to produce better conditions for electro-deposition. It was found advantageous to add small a­mounts of sodium lauryl sulfate and ammonium sulfite to the electrolyte.

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Der Kurzkommentar zur ZPO erlaubt in handlicher Form einen schnellen Zugriff auf das schweizerische Zivilverfahrensrecht. In knapper und übersichtlicher Darstellung werden die wesentlichen Fragestellungen analysiert und die wichtigsten Argumente und Gegenargumente zu umstrittenen Punkten für die Praxis verfügbar gemacht. Zur Neuauflage Für die 2. Auflage wurde der Kommentar umfassend aktualisiert und überarbei- tet. Die Nutzerinnen und Nutzer erhalten damit ein kompaktes Arbeitsmittel auf dem Stand Frühjahr 2013. Berücksichtigt werden insbesondere: − das neue Erwachsenenschutzrecht − die am 1.5.2013 in Kraft getretenen neuen Protokollierungsvorschriften für die Zeugeneinvernahme − die inzwischen schon zahlreichen Weichenstellungen in der Rechtsprechung zur schweizerischen Zivilprozessordnung − die seit 2011 erschienene praxisrelevante neue Literatur (inkl. Neuauflage des BSK ZPO

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Vorbesitzer: Salomo Kohn

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u.a.: Aufsatz von David Asher "Schelling und Schopenhauer"; Wille in der Natur; Photographie; Seidemann;

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Vorbesitzer: Dominikanerkloster Frankfurt am Main;

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Franz Wallner, Alexandre Dumas, Wilhelm Keller, Vorschlag, ein Theaterstück für ihn zu bearbeiten, Idee zu einer Posse, Vorschlag einer Hampelmann-Bühnenfassung