Resolución No. 194: Por medio de la cual se resuelve un recurso de reposición y se concede un recurso de apelación

Servicios registrales

Six Mile Creek Presbyterian Church, Lancaster County, SC Records - Accession 194 - M86 (110)

The Six Mile Presbyterian Church, Lancaster County, SC Records consist of photocopies of a Six Mile Creek Presbyterian Church ledger, containing minutes of church meetings, registers of pastors, elders and deacons, minutes of the church session, registers of communicants, baptisms and deaths. Six Mile Presbyterian Church was started organized sometime around 1804. Included is a note stating the original ledger was rebound in 1971.

Il corpo della cittadina. La costruzione del discorso pubblico sulla legge n. 194/1978 in Italia negli anni Settanta.

In un arco temporale che copre il decennio settanta, ma che si spinge fino ad analizzare anche il dibattito italiano odierno, la presente ricerca ricostruisce i passaggi attraverso i quali l’aborto, da pratica clandestina, è diventato un “fatto” che ha creato e cambiato l’opinione pubblica italiana. Non si tratta di una ricostruzione cronologica pura e semplice, ma quello che si propone è un percorso che procede per temi, utilizzando una particolare chiave di lettura delle fonti giornalistiche e degli atti parlamentari che documentano la costruzione complessiva del discorso. In tale prospettiva, un particolare rilievo assumono alcuni momenti della storia italiana che, nell’arco del decennio, hanno favorito l’immissione di un argomento così complesso, delicato e inusuale come il corpo riproduttivo delle donne sulla scena pubblica, facendone un tema da agenda politica dei partiti. Tra gli eventi più significativi che la ricerca individua certamente il processo a Gigliola Pierobon, avvenuto a Padova nel 1973, di cui si propone una lettura attraverso la chiave interpretativa dell’affaire. Si tratta di una forma di costruzione discorsiva di un “fatto di legge” codificata da Voltaire nel XVIII secolo e ripresa attraverso gli studi dell’antropologa Elisabeth Claverie e del sociologo Luc Boltanski , che applicano in maniera diacronica il concetto di “affaire” a diverse “situazioni di conflitto”, strutturando in tal modo il concetto di “verità contro la legge” . La ricerca è stata condotta utilizzando sia fonti giornalistiche che da diversi punti di vista, hanno fotografato e “tradotto” per l’opinione pubblica il dibattito culturale e politico sul tema dei diritti riproduttivi, sia utilizzando gli atti parlamentari ufficiali , cioè le trascrizioni delle sedute del dibattito alla Camera e al Senato che tra il 1976 e il 1978 hanno creato i presupposti per la nascita della legge 194.

Noise mapping of highly trafficked roads of the province of Bologna according to D.Lgs. 194/2005

The European Community has stressed the importance of achieving a common understanding to deal with the environmental noise through community actions of the Member States. This implies the use of harmonized indicators and specific information regarding the values of indicators, the exceedance of limits and the number of people and dwellings exposed to noise. The D.Lgs. 149/2005 in compliance with the European Directive 2002/49/EC defines methodologies, noise indicators and types of outputs required. In this dissertation the work done for the noise mapping of highly trafficked roads of the Province of Bologna will be reported. The study accounts for the environmental noise generated by the road infrastructure outside the urban agglomeration of Bologna. Roads characterized by an annual traffic greater than three millions of vehicles will be considered. The process of data collection and validation will be reported, as long as the implementation of the calculation method in the software and the procedure to create and calibrate the calculation model. Results will be provided as required by the legislation, in forms of maps and tables. Moreover results regarding each road section accounted will be combined to gain a general understanding of the situation of the overall studied area. Although the understanding of the noise levels and the number of people exposed is paramount, it is not sufficient to develop strategies of noise abatement interventions. Thus a further step will be addressed: the creation of priority maps as the basis of action plans for organizing and prioritizing solutions for noise reduction and abatement. Noise reduction measures are reported in a qualitative way in the annex and constitute a preliminary research.

Mutagenesis and computer modeling studies of a GPCR conserved residue W5.43(194) in ligand recognition and signal transduction for CB2 receptor

W5.43(194), a conserved tryptophan residue among G-protein coupled receptors (GPCRs) and cannabinoid receptors (CB), was examined in the present report for its significance in CB2 receptor ligand binding and adenylyl cyclase (AC) activity. Computer modeling postulates that this site in CB2 may be involved in the affinity of WIN55212-2 and SR144528 through aromatic contacts. In the present study, we reported that a CB2 receptor mutant, W5.43(194)Y, which had a tyrosine (Y) substitution for tryptophan (W), retained the binding affinity for CB agonist CP55940, but reduced binding affinity for CB2 agonist WIN55212-2 and inverse agonist SR144528 by 8-fold and 5-fold, respectively; the CB2 W5.43(194)F and W5.43(194)A mutations significantly affect the binding activities of CP55940, WIN55212-2 and SR144528. Furthermore, we found that agonist-mediated inhibition of the forskolin-induced cAMP production was dramatically diminished in the CB2 mutant W5.43(194)Y, whereas W5.43(194)F and W5.43(194)A mutants resulted in complete elimination of downstream signaling, suggesting that W5.43(194) was essential for the full activation of CB2. These results indicate that both aromatic interaction and hydrogen bonding are involved in ligand binding for the residue W5.43(194), and the mutations of this tryptophan site may affect the conformation of the ligand binding pocket and therefore control the active conformation of the wild type CB2 receptor. W5.43(194)Y/F/A mutations also displayed noticeable enhancement of the constitutive activation probably attributed to the receptor conformational changes resulted from the mutations.