Search for signature inversion in the pi i(13/2)circle times nu i(13/2) bands in Au-182,Au-184,Au-186

Search for low-spin signature inversion in the pi i(13/2) circle times nu i(13/2) bands in odd-odd Au-182,Au-184,Au-186 has been conducted through the standard in-beam gamma-spectroscopy techniques via the Sm-152(Cl-35,5n) Au-182, Yb-172(F-19,5n) (186)An, and Tb-159(Si-29,4n) (184)An reactions, respectively. The pi i(13/2) circle times nu i(13/2) bands in these three nuclei have been identified and extended up to high-spin states. In particular, the inter-band connection between the pi i(13/2) circle times nu i(13/2) band and the ground-state band in Au-184 has been established, leading to a firm spin-and-parity assignment for the pi i(13/2) circle times nu i(13/2) band. The low-spin signature inversion is found in the pi i(13/2) circle times nu i(13/2) bands according to our spin-assignment and-the signature crossing observed at high-spin states.

C 182 INST-D 2013. 363 Hamacas tejidas en hilos de algodón de diversos colores y decoración con flecos (Casanare)

36 fotografías a color.

Potential roles for differential body size and microhabitat complexity in mediating biotic interactions within invasive freshwater amphipod assemblages

Cannibalism and intraguild predation (IGP) are common amongst freshwater amphipod crustacean aswsemblages, particularly between individuals of different body size, with IGP of smaller by larger species. The decline of Gammarus tigrinus Populations in mainland Europe has been accompanied by the arrival of the Ponto-Caspian invader Dikerogammarus villosus and previous studies have implicated IGP of G. tigrinus by the larger D. villosus as the principal driving force in this replacement. We examined how factors such as microhabitat and body size may mediate both cannibalism within G. tigrinus populations and IGP by D. villosus and thus contribute to field patterns of coexistence and exclusion. A field Survey of an invaded Dutch fake indicated that G. tigrinus and D. villosus differed in distribution. with D. villosus being the numerically dominant amphipod (80-96 %) on the rocky boulder Substrate of the shoreline and G. tigrinus being the dominant amphipod (100 %) in the crushed shell/sand matrix immediately adjacent to this. Laboratory microcosm experiments indicated that G. tigrinus cannibalism, particularly of smaller by larger size classes, may be common. In addition, although D. villosus predation of all G. tigrinus size classes was extreme, the smallest size classes Suffered the highest predation. Indeed, when exposed to D. villosus, predation of larger G. tigrinus was lowest when smaller G. tigrinus were also present. Increasing microhabitat complexity from a simple bare substrate littered with Dreissena polymorpha zebra mussels to a Crushed shell/sand matrix significantly reduced both cannibalism and IGP. Our Study emphasizes the need to consider both life history stages and habitat template, when considering the impacts of biotic interactions and it also emphasizes that complex, interacting factors may be mediating the range expansion of D. villosus.

Genomic, Epigenomic and Transcriptomic Molecular Characterization of Splenic Marginal Zone Lymphoma Reveals Recurrent Abnormalities in miR-182

Splenic marginal zone lymphoma (SMZL) is a low grade B-cell non-Hodgkin's lymphoma. The molecular pathology of this entity remains poorly understood. To characterise this lymphoma at the molecular level, we performed an integrated analysis of 1) genome wide genetic copy number alterations 2) gene expression profiles and 3) epigenetic DNA methylation profiles.We have previously shown that SMZL is characterised by recurrent alterations of chromosomes 7q, 6q, 3q, 9q and 18; however, gene resolution oligonucleotide array comparative genomic hybridisation did not reveal evidence of cryptic amplification or deletion in these regions. The most frequently lost 7q32 region contains a cluster of miRNAs. qRT-PCR revealed that three of these (miR-182/96/183) show underexpression in SMZL, and miR-182 is somatically mutated in >20% of cases of SMZL, as well as in >20% of cases of follicular lymphoma, and between 5-15% of cases of chronic lymphocytic leukaemia, MALT-lymphoma and hairy cell leukaemia. We conclude that miR-182 is a strong candidate novel tumour suppressor miRNA in lymphoma.The overall gene expression signature of SMZL was found to be strongly distinct fromthose of other lymphomas. Functional analysis of gene expression data revealed SMZL to be characterised by abnormalities in B-cell receptor signalling (especially through the CD19/21-PI3K/AKT pathway) and apoptotic pathways. In addition, genes involved in the response to viral infection appeared upregulated. SMZL shows a unique epigenetic profile, but analysis of differentially methylated genes showed few with methylation related transcriptional deregulation, suggesting that DNA methylation abnormalities are not a critical component of the SMZL malignant phenotype.

Recueil de chartes de commune.

Contient : Châteauvillain ; Troyes ; Nogaro en Armagnac ; Narbonne ; La Beuvrière (cf. fol. 73) ; Reims ; Troyes ; Beaumont ; Châteauvillain (1236 ; cf. fol. 2) ; La Chapelle [d'Angillon] ; Joigny ; Lorris ; Dixmont ; Montargis ; Barcelone (cf. fol. 149) ; Selens et Saint-Aubin ; La Beuvrière (cf. fol. 14) ; Chaumont ; Saint-Bris ; Saint-Laurent-sur-Barenjon ; Voisines ; Le Moulinet ; Barlieu ; Crespy [-en-Valois] ; Montdidier ; Laon ; Soissons ; Abbeville ; Compiègne ; Saint-Quentin ; Corbie ; Saint-Josse-sur-Mer ; La Fère ; Beauvais ; Nanteuil ; Courmelles ; Breteuil ; Beaumont-en-Argonne ; Chaumont ; Saint-Omer ; Vaux près Mouzon ; Vaux, Saconin, Mercin ; Chacrise ; Tournai ; Crandelain, etc ; Ambleteuse ; Morsain, etc ; Mantes ; Ferrières ; Aizy ; Pargny ; Saint-Riquier ; Soissons ; Saint-Martin d'Issoudun (cf. fol. 182) ; Rouen ; Dreux ; Meaux ; Reims ; Chablis ; Chatillon-sur-Seine ; Sens ; Auxerre ; Cerny ; Dixmont ; Étampes ; Orléans ; Bourges ; Issoudun (cf. fol. 148) ; Beaufort-en-Vallée ; La Rochelle ; Villefranche [d'Allier] ; Montauban ; Nevers ; Castres ; Toulouse ; Habitants de la Terre d'Albigeois ; Aigues-Mortes ; Lorrez-le-Bocage ; Le Puy ; Saint-Céré ; Barcelone ; Chatillon-sur-Marne ; Raucourt et Héraucourt ; Mézières ; Chatillon-sur-Marne ; Saint-Hellier ; Coutumes d'Anjou et du Maine ; Ervy-le-Chatel ; Cerres, Montceaux, Chaussepierre ; Notice sur un ms. de Chroniques françaises, de la bibliothèque de Colbert (= Duchesne 79)

The Columbian, 9 July 1813 (vol. 4, no. 1127) - Newspaper

Volumes of interest were published between 1812 and 1815 with articles about the War of 1812. Issue for July 9, 1813 includes a report of the Battle of Beaver Dams. Issue for July 29, 1813 also includes a report of the Battle of Beaver Dams.

HG 182.65-182.75

Light brown sediment with clasts ranging from small to medium in size. The clast shape ranges from sub-angular to sub-rounded. Rotation structures can commonly be seen, along with some comet structures as well. A few lineations and edge-to-edge grain crushing can also be observed. There is also the inclusion of a fine grained domain that is a darker brown (tanned-brown).

HG 182.65-182.75A

Light brown sediment with clasts ranging from small to medium in size. Clast shape ranges from angular to sub-rounded. Rotation structures are abundant throughout the sample. Comet structures and lineations can also be seen.

L’effectivité des Conventions 29, 138 et 182 de l’Organisation internationale du travail sur l’éradication du travail des enfants en Mauritanie

L’objectif de cette étude consiste à déterminer si les conventions de l’Organisation internationale du travail (OIT) sont effectives en ce qui concerne l’éradication du travail des enfants en Mauritanie. Cette effectivité est appréciée en mesurant la réception juridique et la réception sociale en Mauritanie de la Convention 29 sur le travail forcé, de la Convention 138 sur l’âge minimum d’admission à l’emploi et de la Convention 182 sur les pires formes de travail des enfants. La réception juridique des conventions est mesurée par un examen de l’intégration de leurs dispositions dans le droit national mauritanien. La réception juridique comprend également l’appréciation du contrôle du respect des conventions en territoire mauritanien. La réception sociale fait référence, quant à elle, aux stratégies de mise en œuvre des conventions de l’OIT par le Gouvernement mauritanien à travers ses programmes et ses politiques. Notre analyse démontre que l’effectivité des Conventions 29, 138 et 182 de l’OIT en ce qui concerne l’éradication du travail des enfants en Mauritanie est, selon nous, partielle. Dans l’ensemble, la situation tend à s’améliorer et le Gouvernement mauritanien tente de respecter l’esprit de ces conventions et de leur faire écho dans le droit national. Toutefois, il n’existe pas beaucoup d’information sur l’impact des programmes mis en place pour éradiquer le travail des enfants.

Decreto Rectoral No.1127 : Por el cual se establecen los requisitos para reconocer los estudios de formación sacerdotal con el plan de estudios del programa de pregrado de Artes Liberales en Ciencias Sociales ofrecido en la Universidad del Rosario

Establecen los requisitos para reconocer los estudios de formación sacerdotal con el plan de estudios del programa de pregrado de Artes Liberales en Ciencias Sociales ofrecido en la Universidad del Rosario.

Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells

Cell culture models of antioestrogen resistance often involve applying selective pressures of oestrogen deprivation simultaneously with addition of tamoxifen or fulvestrant (Faslodex, ICI 182,780) which makes it difficult to distinguish events in development of antioestrogen resistance from those in loss of response to oestrogen or other components. We describe here time courses of loss of antioestrogen response using either oestrogen-maintained or oestrogen-deprived MCF7 cells in which the only alteration to the culture medium was addition of 10(-6) M tamoxifen or 10(-7) M fulvestrant. In both oestrogen-maintained and oestrogen-deprived models, loss of growth response to tamoxifen was not associated with loss of response to fulvestrant. However, loss of growth response to fulvestrant was associated in both models with concomitant loss of growth response to tamoxifen. Measurement of oestrogen receptor alpha (ER alpha) and oestrogen receptor beta (ER beta) mRNA by real-time RT-PCR together with ER alpha and ER beta protein by Western immunoblotting revealed substantial changes to ER alpha levels but very little alteration to ER beta levels following development of antioestrogen resistance. In oestrogen-maintained cells, tamoxifen resistance was associated with raised levels of ERa mRNA/protein. However by contrast, in oestrogen-deprived MCF7 cells, where oestrogen deprivation alone had already resulted in increased levels of ERa mRNA/protein, long-term tamoxifen exposure now reduced ER alpha levels. Whilst long-term exposure to fulvestrant reduced ERa. mRNA/protein levels in the oestrogen-maintained cells to a level barely detectable by Western immunoblotting and non-functional in inducing gene expression (ERE-LUC reporter or pS2), in oestrogen-deprived cells the reduction was much less substantial and these cells retained an oestrogen-induction of both the ERE-LUC reporter gene and the endogenous pS2 gene which could still be inhibited by antioestrogen. This demonstrates that whilst ER alpha can be abrogated by fulvestrant and increased by tamoxifen in some circumstances, this does not always hold true and mechanisms other than alteration to ER must be involved in the development of antioestrogen resistant growth. (c) 2006 Elsevier Ltd. All rights reserved.

Are shocks to energy consumption permanent or temporary? evidence from 182 countries

This article applies univariate and panel data unit root tests to annual panel data for 182 countries over the period 1979–2000 to examine the stationarity properties of per capita energy consumption. The univariate unit root test can only reject the unit root null for 56 countries or 31% of the sample at the 10% level or better. However, univariate unit root tests have low power with short spans of data and therefore failure to reject the unit root null should be treated with caution. When we apply the panel data unit root test we find overwhelming evidence that energy consumption is stationary. We discuss the policy implications of these findings and offer suggestions for future research.