Flora polínica da reserva do parque estadual das fontes do Ipiranga (São Paulo, SP, Brasil). Famílias: 141-Boraginaceae e 149-Gesneriaceae

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

George C. Martin Papers - Accession 271 - M117 (149-150)

The George C. Martin Papers includes Civil War correspondence between George Canning Martin and his wife, Sarah Jane, from May 1862 to August 1864. Subjects include camp life, the progress of the war in North Carolina and Virginia, and the physical and mental condition of the Confederate soldiers (such as ill health, poor food, and depression). Also included are tax receipts, pension records, newspapers clippings (1863), a commonplace book belonging to Robert Smith, and a memoir (author unknown).

Folate Receptor Targeted Alpha-Therapy Using Terbium-149

Terbium-149 is among the most interesting therapeutic nuclides for medical applications. It decays by emission of short-range α-particles (Eα = 3.967 MeV) with a half-life of 4.12 h. The goal of this study was to investigate the anticancer efficacy of a 149Tb-labeled DOTA-folate conjugate (cm09) using folate receptor (FR)-positive cancer cells in vitro and in tumor-bearing mice. 149Tb was produced at the ISOLDE facility at CERN. Radiolabeling of cm09 with purified 149Tb resulted in a specific activity of ~1.2 MBq/nmol. In vitro assays performed with 149Tb-cm09 revealed a reduced KB cell viability in a FR-specific and activity concentration-dependent manner. Tumor-bearing mice were injected with saline only (group A) or with 149Tb-cm09 (group B: 2.2 MBq; group C: 3.0 MBq). A significant tumor growth delay was found in treated animals resulting in an increased average survival time of mice which received 149Tb-cm09 (B: 30.5 d; C: 43 d) compared to untreated controls (A: 21 d). Analysis of blood parameters revealed no signs of acute toxicity to the kidneys or liver in treated mice over the time of investigation. These results demonstrated the potential of folate-based α-radionuclide therapy in tumor-bearing mice.

Ms. hebr. oct. 149 - Shevile emunah

Vorbesitzer: Abraham Merzbacher

Ms. Barth. 149 - Rechtsbücher aus Lothringen

Vorbesitzer: Phillips vom Hage; Bartholomaeusstift Frankfurt am Main.

Comparative Cytotoxicity Study of Silver Nanoparticles (AgNPs) in a Variety of Rainbow Trout Cell Lines (RTL-W1, RTH-149, RTG-2) and Primary Hepatocytes.

Among all classes of nanomaterials, silver nanoparticles (AgNPs) have potentially an important ecotoxicological impact, especially in freshwater environments. Fish are particularly susceptible to the toxic effects of silver ions and, with knowledge gaps regarding the contribution of dissolution and unique particle effects to AgNP toxicity, they represent a group of vulnerable organisms. Using cell lines (RTL-W1, RTH-149, RTG-2) and primary hepatocytes of rainbow trout (Oncorhynchus mykiss) as in vitro test systems, we assessed the cytotoxicity of the representative AgNP, NM-300K, and AgNO3 as an Ag+ ion source. Lack of AgNP interference with the cytotoxicity assays (AlamarBlue, CFDA-AM, NRU assay) and their simultaneous application point to the compatibility and usefulness of such a battery of assays. The RTH-149 and RTL-W1 liver cell lines exhibited similar sensitivity as primary hepatocytes towards AgNP toxicity. Leibovitz's L-15 culture medium composition (high amino acid content) had an important influence on the behaviour and toxicity of AgNPs towards the RTL-W1 cell line. The obtained results demonstrate that, with careful consideration, such an in vitro approach can provide valuable toxicological data to be used in an integrated testing strategy for NM-300K risk assessment.

Ms. Praed. 149 - [Sammelband in 3 Teilen: Konvolut aus Handschrift, Inkunabel und Postinkunabel]

Vorbesitzer: F.K.D.D.O.P.; F.K.D.D.P.M.Q.P.F.; Dominikanerkloster Frankfurt am Main

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 149 - Bericht über negative Rezensionen von Veröffentlichungen Schopenhauers

u.a.: kritische Auseinandersetzung mit den Publikationen von Schopenhauer "Über den Willen der Natur", "Die beiden Grundprobleme der Ethik"; Immanuel Kant; Friedrich Schleiermacher, Andreas Ludwig;

Na 50 Nachlass Arthur Schopenhauer - 'Schopenhauer-Archiv', 898 - Maßnahmen gegen die vorgeworfenen Beleidigungen Karl Gutzkows an Schopenhauer

u.a. Erkundigung nach Verwandte Schopenhauers; Vorbereitung für die Anklage;

Ms.Ff.F.Stoltze 3. 149 - Brief von Gustav Kanngießer an Friedrich Stoltze

Verabredung zu einem Treffen

Ms. Ff. Mus. 762 - Psalm 149, V 1

[Georg Philipp Telemann]

Na 1 Nachlass Max Horkheimer, 686 - Rosenzweig-Test, "Art Project on Fascist Agitator" (p. IX 148.1-2 - IX 149.1-7)

Zum Rosenzweig-Test, 1945; Brown, J.F.: "Memorandum on the Modification of the Rosenzweig Picture Frustration Test". Typoskript, 3 Blatt; Rosenzweig, Saul. "The Picture-Association Method and Its Application in a Study of Reactions to Frustration.", Sonderdruck aus: Journal of Personality, September 1945, S. 3-23; Materialien zum "Art Project on Fascist Agitator" (1945):; 1. "What is a Fascist Agitator?", a) Typoskript, 1 Blatt, b) Typoskript mit handschriftlichen Korrekturen, 2 Blatt; 2. "Some Traits of the Fascist Agitator". Typoskript, 5 Blatt; 3. "Pamphlet", a) Typoskript, 1 Blatt, b) Typoskript, 1 Blatt, c) Typoskript mit dem Titel 'Devices of the Agitator', 1 Blatt; 4. Max Horkheimer: eigenhändige Notizen über den Agitator, 1 Blatt; 5. "Quotes from the Agitator (pages refer to Leo Löwenthals manuscript vol. III)". Typoskript, 7 Blatt; 6. Adressenlisten, 3 Blatt; 7. Materialien zum 'Agitator-Projekt': Photos, Reproduktionen von Zeichnungen und Zeitungsausschnitten;

Ms. lat. oct. 149 - In Thomae de Aquino Summam theologiae, P. II., 2.

Vorbesitzer: Johannes Bartholomaei

(Table 1) Element analyses of DSDP Hole 15-149

An iridium anomaly has been found in coincidence with the known microtektite level in cores from Deep Sea Drilling Project site 149 in the Caribbean Sea. The iridium was probably not in the microtektites but deposited simultaneously with them; this could occur if the iridium was deposited from a dust cloud resulting from a bolide impact, as suggested for the anomaly associated with the Cretaceous-Tertiary boundary. Other workers have deduced that the microtektites are part of the North American strewn tektite field, which is dated at about 34 million years before present, and that the microtektite horizon in deep-sea cores is synchronous with the extinction of five radiolarian species. Mass extinctions also occur in terrestrial mammals within 4 million years of this time. The iridium anomaly and the tektites and microtektites are supportive of a major bolide impact about 34 million years ago.