983 resultados para medicinal plants toxicity


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Endive (Cichorium intybus) is one of the vegetables least studied in Brazil with respect to the behavior of the most commercialized cultivars, but it is known that the number of plants per area is one of the factors that most influences the productivity of various crops. Thus, the objective of this work was to evaluate the behavior of endive using four spacings between rows and five spacings between plants, in the region of Jaboticabal-SP. The experiment was conducted in the field in the period of August 12, 2008 to November 6, 2008, in the experimental area of the Sector of Vegetable Crops and Aromatic-Medicinal Plants, Department of Crop Sciences, School of Agricultural and Veterinary Sciences - UNESP-FCAV. The experimental design utilized was a randomized block design with a 4 × 5 factorial scheme, i.e., four spacings between rows (0.15, 0.20, 0.25 and 0.30 m) and five spacings between plants (0.10, 0.15, 0.20, 0.25 and 0.30 m), with three repetitions. The endive cultivar studied was 'Pão-de-Acucar', obtained from the company Tecnoseed. Seedlings were established utilizing the sowing system in 200-cell Styrofoam trays containing the substrate Plantmax Vegetables® HA. The seedlings were transplanted at 37 days after planting. After harvesting, the following characteristics were determined: height (cm), diameter of the plant in rows (cm), diameter of the plant in between rows (cm), number of leaves, fresh weight (g) and total estimated productivity (t/ha). There were no interactions between the factors studied. Based on the data, we conclude that spacings of 0.15 m between rows and of 0.15 m between plants produce plants of higher quality and with greater productivity.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Environmental problems caused by synthetic fungicides have increased the search for alternative methods of control of plant diseases. The objective was to evaluate the effect of essential oil of citronella grass, on the fungus Rhizoctonia solani, in different methods of in vitro fungitoxicity. We used a randomized design in a factorial design with four replications, where the factors were composed of four methods for assessing the in vitro fungitoxicity of the essential oil of citronella grass (essential oil diluted in Tween 80 (0.5%) and embedded in the culture medium PDA (potato dextrose agar) still melting, essential oil diluted in Tween 80 (0.5%) and distributed on the surface of the PDA; oil essential diluted in Tween 80 (0.5%) and distributed on filter paper attached to the inner surface of the lid of the Petri dish, pure essential oil and distributed on the surface of the culture medium, and control) and five evaluation periods (2, 4, 6, 8 and 10 days of incubation). Was used 0.25μL mL-1 of citronella oil in all treatments. Of the treatments evaluated the use of pure oil distributed on the surface of the culture medium was more effective in reducing the mycelial diameter in all evaluations. In this method the rate of mycelial growth was 9,02 mm day-1, reaching in last evaluation 79,77 mm.

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Nephrolithiasis (kidney stones) can be seen as a common clinical condition responsible for substantial economic, social and psychological costs, due to its high morbidity, especially since it affects adults in their productive phase. Its development in the urinary tract is a complex and multifactorial process. The majority of kidney stones are made of calcium oxalate. A lot of plants are used to treat nephrolithiasis and they often exhibit calcium oxalate crystals in the parts that are employed for this medicinal purpose, representing a possible risk. In this light, we performed a literature review via the databases Scielo, PubMed and Medline and found 28 articles reporting the traditional use of plants in the treatment of nephrolithiasis. The occurrence of calcium oxalate crystals was indicated in 19 species. We argue that the use of these plants could give rise to adverse effects in people who are prone to form calcium oxalate stones in the kidney.

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The wavelength-integrated absorbance (WIA) and summation of absorbance (∑ lines) of different lines were evaluated to enhance sensitivity and determine B, P and S in medicinal plants by HR-CS FAAS. The lowest LOD for B (0.5mgL-1) and P (13.7mgL-1) was obtained by integration of lines 249.773nm (3pixels) and 247.620nm (5pixels), respectively. The ∑ lines for CS at 257.595nm and 257.958nm furnished LOD=30.5mgL-1, ca. 10% lower than the LOD obtained for the WIA using 257.595nm and 5pixels. Data showed the advantage of WIA over ∑ lines to improve sensitivity for all analytes. Under optimized conditions, calibration curves in the 1.0-100mgL-1 B and 50.0-2000mgL-1 P, S ranges were consistently obtained. Results obtained with the HR-CS FAAS method were in agreement at 98% and 95% confidence level with certified values for B and P, respectively. And results for S were in accordance to non-certified values. Concentrations of B, P, and S in 12 medicinal plants analyzed by the proposed method varied within the 19.4-34.5mgkg-1 B, 719-3910mgkg-1 P and 1469-7653mgkg-1 S ranges. © 2012 Elsevier B.V.

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The leaves of Myrcia DC. ex Guill species are used in traditional medicine and are also exploited commercially as herbal drugs for the treatment of diabetes mellitus. The present work aimed to assess the qualitative and quantitative profiles of M. bella hydroalcoholic extract, due to these uses, since the existing legislation in Brazil determines that a standard method must be developed in order to be used for quality control of raw plant materials. The current study identified eleven known flavonoid-O-glycosides and six acylated flavonoid derivatives of myricetin and quercetin, together with two kaempferol glycosides and phenolic acids such as caffeic acid, ethil galate, gallic acid and quinic acid. In total, 24 constituents were characterized, by means of extensive preparative chromatographic analyses, along with MS and NMR techniques. An HPLC-PAD-ESI-ITMS and FIA-ESI-IT-MSn method were developed for rapid identification of acylated flavonoids, flavonoid-O- glycosides derivatives of myricetin and quercetin and phenolic acids in the hydroalcoholic M. bella leaves extract. The FIA-ESI-IT-MS techinique is a powerful tool for direct and rapid identification of the constituents after isolation and NMR characterization. Thus, it could be used as an initial method for identification of authentic samples concerning quality control of Myrcia spp extracts. © 2013 by the authors.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Ciências Biológicas (Farmacologia) - IBB

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Pós-graduação em Ciências Biológicas (Farmacologia) - IBB

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)