MicroRNA regulation and the variability of human cortical gene expression

Understanding the driving forces of gene expression variation within human populations will provide important insights into the molecular basis of human phenotypic variation. In the genome, the gene expression variability differs among genes, and at prese

Long-term changes and variability of monthly extreme temperatures in India

Extreme temperatures are changing worldwide together with changes in the mean temperatures. This study investigates the long-term trends and variations of the monthly maximum and minimum temperatures and their effects on seasonal fluctuations in various climatological regions in India. The magnitude of the trends and their statistical significance were determined by parametric ordinary least square regression techniques and the variations were determined by the respective coefficient of variations. The results showed that the monthly maximum temperature increased, though unevenly, over the last century. Minimum temperature changes were more variable than maximum temperature changes, both temporally and spatially, with results of lesser significance. The results of this study are good indicators of Indian climate variability and its changes over the last century. © Springer-Verlag 2009.

Transient growth and triggering in the horizontal Rijke tube Matthew

This theoretical paper examines a non-normal and non-linear model of a horizontal Rijke tube. Linear and non-linear optimal initial states, which maximize acoustic energy growth over a given time from a given energy, are calculated. It is found that non-linearity and non-normality both contribute to transient growth and that, for this model, linear optimal states are only a good predictor of non-linear optimal states for low initial energies. Two types of non-linear optimal initial state are found. The first has strong energy growth during the first period of the fundamental mode but loses energy thereafter. The second has weaker energy growth during the first period but retains high energy for longer. The second type causes triggering to self-sustained oscillations from lower energy than the first and has higher energy in the fundamental mode. This suggests, for instance, that low frequency noise will be more effective at causing triggering than high frequency noise.

Effect of weight of otter boards on the horizontal opening of trawl nets

The paper gives briefly the experiments carried out to determine the optimum weight of otter board that should be used for a trawl gear for better efficiency.

Bayesian classification of acoustical waveforms under environmental variability

We present in this paper a new multivariate probabilistic approach to Acoustic Pulse Recognition (APR) for tangible interface applications. This model uses Principle Component Analysis (PCA) in a probabilistic framework to classify tapping pulses with a high degree of variability. It was found that this model, achieves a higher robustness to pulse variability than simpler template matching methods, specifically when allowed to train on data containing high variability. © 2011 IEEE.

Physical and numerical modeling of horizontal gas-hydrate wells

Methane hydrate, which is usually found under deep seabed or permafrost zones, is a potential energy resource for future years. Depressurization of horizontalwells bored in methane hydrate layer is considered as one possible method for hydrate dissociation and methane extraction from the hosting soil. Since hydrate is likely to behave as a bonding material to sandy soils, supported well construction is necessary to avoid wellcollapse due to the loss of the apparent cohesion during depressurization. This paper describes both physical and numerical modeling of such horizontal support wells. The experimental part involves depressurization of small well models in a large pressure cell, while the numerical part simulates the corresponding problem. While the experiment models simulate only gas saturated initial conditions, the numerical analysis simulates both gas-saturated and more realistic water-saturated conditions based on effective stress coupled flow-deformation formulation of these three phases. © 2006 Taylor & Francis Group, London.

The horizontal response of framed buildings on individual footings to excavation-induced movements

Deep excavations and tunnelling can cause ground movements that affect buildings within their influence zone. The current approach for building damage assessment is based on tensile strains estimated from the deflection ratio and the horizontal strains at the building foundation. This paper examines the significance of horizontal strains in buildings on individual footings. The first part of the paper presents a case study of a framed building in Singapore which was subjected to the effects of bored tunnelling, where significant horizontal strains were observed. The second part of the paper suggests a method to relate the horizontal strains induced in a building to the stiffness of the frame structure. Using a combination of simplified structural analysis and finite element models, design guidance is proposed to estimate excavation-induced horizontal strains in frame buildings on individual footings. © 2012 Taylor & Francis Group.