998 resultados para falha na transferência da imunidade
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Pós-graduação em Ciência e Tecnologia de Materiais - FC
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Pós-graduação em Engenharia Mecânica - FEG
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The approach of the subject matter in this work relies on the fact that the reliability of methods for performance analysis of materials proves critical for the result. This work focused on the development and presentation of the methodology for lifting probability curves for fatigue test (SN) according to standard E739, this focus is justified by the fact that the results in fatigue test show considerable dispersion making it difficult to reading and interpretation of data, this dispersion arises because the phenomenon of rupture is strongly influenced by internal characteristics of the material, we can then have much data ranging from test to test. Thus we set out originally for a brief study of aluminum alloys in question, as well as the treatments to which they were subjected. We also studied the behavior of materials when subjected to cyclic loading, which configures process of fatigue failure, and even fatigue test method in question. This statistical analysis is based on the ASTM E739 standard, so its contents was studied in detail so that we could present in detail the methodology and raise SN curves for different aluminum alloy 7012 subjected to fatigue test. Data were collected from tests conducted in the department of materials from two samples of aluminum alloy 7012 solubilized and precipitated by different time intervals and assayed temperature fatigue-type traction-compression, these data were then analyzed and used to survey curves using the base as E739. After lifting the curve analyzed the characteristics of the test samples and their correlation with the test results. We confirmed the effectiveness of the method of statistical analysis by ASME E739, which allowed the reading of data without this method would be very difficult to have a reading and comparison of the results for the two types... (Complete abstract click electronic access below)
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The Santos Basin is located in the Brazilian continental margin and includes the coast of Santa Catarina, Paraná, São Paulo and Rio de Janeiro states. Its northern limit is the Campos Basin through the High of Cabo Frio and the southern one with the Pelotas Basin through the Platform of Florianópolis, totaling an area of approximately 350,000 square kilometers in a water depth of 3,000 m. The Paranapanema Lineament has WNW / ESE direction, and extends from the area filled by the Paraná Basin, on the border between the states of Sao Paulo and Parana, lasting up to near the ocean floor along with the fracture zone of Rio de Janeiro. The Capricorn Lineament is a feature inherited from the separation between the continents of Africa and South America, and is the main structural feature NW / SE of the Santos Basin center-south region. These two structures together with other ones with continental origin may be associated with structural features in the sediments from the Santos Basin. This work aims to characterize the structures operating in the central portion of the Santos Basin based on subsurface data in the offshore area (2D seismic) together with data from the surface of the continental basement in a way to correlate the Santos Basin structures with the continental regional traits. This data interpolation showed that the structural features of the continent operates on the submerged zone, the seismic sections show these structural trends for the Paranapanema Lineament / Fracture Zone of Rio de Janeiro, Capricorn Lineament and two fault zones that exhibit structures typical of a transfer zone
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The Vazante Fault Zone (VFZ), located northwestward of Minas Gerais, host the largest zinc deposit known in the Brazilian territory. This structure is hosted in Vazante’s Group rocks, a metassedimentary sequence of marine environment. Near Vazante is situated the south end of the VFZ. To the west, occur the Serra do Garrote inflexion, characterized by a curvature in the contact of Formations Serra do Garrote and Serra do Poço Verde. This structure is through the analysis of aerial imagery of the region and represented in the published geological maps. The objective of this work is to understand what causes this inflexion and determine whether it affects the VZF, causing a shift in the same, and possibly, in the mineralization as well. To this end, it was done a mapping work in the region covering the Serra do Garrote inflexion and the south end of the VFZ, in 1:25.000 scale, supplemented by petrographic description of thin section and geologic sections, with cooperated to the understanding of the structural evolution of the region. Data analysis allowed the identification of six deformation phases. The D1 an D2 phases generated the main foliation. The D3 phase generate kink bands folds, with NS axis and vertical axial plane. The fourth phase is responsible for generating the Vazante Fault Zone. The fifth phase produces low angle folds and shear zones, subparallel to S1//S2. The last phase generates folds with NW axis and vertical axial plane, with causes the inflection of lithologic contactas. Field observations also make possible the conclusion that the Vazante Fault Zone presents a south continuation, which is affected by deformation associated to D6 phase attributing to the trace of the VFZ a curved geometry, similar to that exhibited by lithologic contacts between units of the map
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Nowadays technological trend is based on finding materials that could support low weight with satisfactory mechanical properties and for this reason composite material became a very attractive topic in research projects all over the world. Due to its heterogenic properties, this type of material shows scatter in mechanical test results, especially in cyclic loading. Therefore it is important to predict its fatigue strength behaviour by statistic analysis, once fatigue causes approximately 90% of the failure in structural components. The present work aimed to investigate the fatigue behaviour of the Twill/Cycom 890 composite, which is carbon fiber reinforced with polymeric resin as matrix and manufactured via RTM process (Resin Transfer Molding). All samples were tested in different tensile level in triplicate in order to associate these values. The statistical analysis was conducted with Two-Parameter Weibull Distribution and then evaluated the fatigue life results for the composite. Weibull graphics were used to determine the scale and shape parameters. The S-N curve for the Twill/Cycom composite was drawn and indicated the number of cycles to occur the first damages in this material. The probability of failure was associated with material reliability, as shown in graphics for the different tensile levels and fatigue life. In addition, the laminate was evaluated by ultrasonic inspection showing a regular impregnation. The fractographic analysis conducted by SEM showed failure mechanisms for polymeric composites associated to cyclic loadings ... (Complete abstract click electronic access below)
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This paper studies the frame deformations on a formula SAE vehicle in steady-state cornering and its influence on the lateral load transfers and, consequently, on the tires normal loads due to the applied lateral load. For a vehicle with a perfect rigid frame, the vehicle mass, the position of the center of gravity and the suspensions are the only factors responsible for the load distribution between the tires. When the frame deformations are no longer negligible, the frame deformations affect the loaddistribution between the tires. The frame flexibility turns it able to behave as an additional set of springs to the suspension system, thus changing the behavior of the set. This paper describes howit happens and suggests ways to minimize this phenomenon
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Infertility is directly related to chromosomal abnormalities in germ cells. Among them, the aneuploidies are the most frequent chromosomal abnormalities and responsible for embryo implantation failures, miscarriages, fetal losses and newborns with congenital malformations, mental disability and neuropsychomotor developmental delay. Male patients with normal somatic karyotype may present different rates of aneuploidies in sperm, resulting in abnormal embryos. This study aimed to correlate the frequency of chromosomal aneuploidies in spermatozoa with embryo implantation rate in couples undergoing assisted reproductive techniques. The methodology has included chromosomal analysis by GTG banding and molecular cytogenetic study using Fluorescent In Situ Hybridization technique for evaluation of chromosomes 9, X and Y in germ cells of 22 patients referred to the Human Reproduction Service of the Clinical Hospital FMRP-USP. Embryo implantation rates were determined by hormonal evaluation in maternal peripheral blood and ultrasound confirmation. Two patients presented abnormal karyotype, characterized by polymorphism of the heterochromatic region of the long arm of chromosome 9 and a satellite in the short arm of chromosome 22. Both alterations, usually considered variants of normality, have been related to infertility phenotype and miscarriages. Significant differences were detected between couples who presented pregnancy (group 1) and couples with embryo implantation failure (group 2), with higher frequency of aneusomy and diploidy of chromosome 9, as well as total aneuploidy in sperm of group 2 patients. Our results suggest a correlation between aneuploidy and embryo implantation rates, since the infertile group with reproductive failure has showed higher frequency of aneuploidy. Screening for aneuploidies detection in male germ cells should be included in order to decrease embryo implantation failures, miscarriages and fetuses with chromosomal ...
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Este trabalho apresenta a Caracterização Estrutural da Zona de Falha da Cachoeira na região compreendida entre as cidades de Jundiaí e Monte Mor no estado de São Paulo. A Zona da Falha da Cachoeira constitui um importante alinhamento estrutural de direção NW no Embasamento Cristalino e adentra-se no mesmo sentido na Bacia do Paraná afetando os sedimentos paleozóicos. Para a investigação da Zona de Falha foi necessária a definição das características geológico-estruturais e tectônicas da área. As análises macro e mesoscópicas indicam forte estruturação de relevo e dos alinhamentos de drenagem para direção NW-SE e subordinadamente para NE-SW. A zona de falha é marcada pela presença de rochas com texturas miloniticas, cataclásticas e trama de cristais isorientados não deformados. Falhas normais, transcorrentes dextrais, sinistrais foram identificadas e suas análises permitiram inferir um quadro evolutivo para a zona da Falha da Cachoeira, onde as falhas de direções NW-SE antigas relacionadas à paleotectônica e a formação das rochas miloniticas e cataclásticas , as NE-SW aos falhamentos normais da tectônica distensiva do sistema rifts do Sudeste Brasileiro que geraram os depósitos terciários e as falhas normais NW-SE a aos movimentos transcorrentes neotectônicos.
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A Zona de Falha de Cássia constitui um feixe de falhas de direção preferencial NW-SE e aproximadamente 2 km de largura. Dados de campo, petrográficos e microestruturais evidenciam uma longa história deformacional da zona de falha. Assim, foram caracterizadas três fases de atividade/movimentação da Zona de Falha de Cássia. A primeira fase (précambriana) é caracterizada por deformação em regime dúctil, acarretando na geração de milonitos formados em condições metamórficas de fácies xisto verde. Este é o estágio de formação da falha, apresentando caráter transcorrente oblíqua, com movimentação sinistral inversa. A segunda fase corresponde a uma reativação da zona de falha como uma falha normal, com bloco alto a NE e bloco baixo a SW da referida estrutura. Seu registro é dado pela ocorrência localizada de brechas e cataclasitos. Este episódio de deformação eminentemente rúptil é correlacionado com o Soerguimento do Alto Paranaíba, o que indica movimentação da falha no Neocretáceo. A terceira e última fase é marcada pela formação de depósitos sedimentares plio-pleistocênicos compostos por brecha sedimentar de leques aluviais e sedimentos argilosos lacustres. Tais depósitos são interpretados como originados pelo represamento da drenagem subatual e conseqüente mudança do nível de base local, em decorrência de uma reativação da Zona de Falha de Cássia. O referido pacote sedimentar apresenta-se localmente cortado por fraturas, zonas brechadas e falhas, caracterizando atividade neotectônica na região. Além disso, foi mostrada a forte influência da zona de falha no desenvolvimento da paisagem da região, sendo constatada a inversão do relevo e da drenagem na área estudada.
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Pós-graduação em Medicina Veterinária - FCAV
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This work provides a systematic and critical review of part of the scientific production of its author. It includes three research topics, namely salmonellosis, brucellosis, and leishmaniasis. Each one of these topics is discussed in individual chapters. Most of the data discussed here refers to pathology, pathogenesis, hostpathogen interactions, innate immunity, and diagnosis of these diseases. Instead of being organized as a traditional literature reviews, the chapters actually emphasize the scientific contribution of the author’s publications in each of these fields.
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Pós-graduação em Zootecnia - FCAV
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)