Treatment of condylar fractures with an intraoral approach using an angulated screwdriver: Results of a multicentre study

Background: This multicentre study aimed to investigate long-term radiographic and functional results following the treatment of condylar fractures using an angulated screwdriver system and open rigid internal fixation with an intraoral surgical approach.Methods: Twenty-nine patients with a total of 32 condylar fractures were evaluated. The patients were investigated prospectively based on the following variables: age, sex, aetiology, side, location and classification of the fracture, degree of displacement, associated fractures, surgical approach, oral health status, type of osteosynthesis plate, duration of surgery, mouth-opening, complications, and duration of follow-up.Results: The fractures were classified as subcondylar (n = 25) or condylar neck (n = 7). Mean patient age was 36.38 +/- 16.60 years. The median duration of postoperative follow-up was 24.39 +/- 13.94 months. No joint noise, weakness of the facial nerve, joint pain, or muscle pain was observed. An additional retromandibular approach was necessary to enable the treatment of one subcondylar fracture with medial displacement.Conclusion: Subcondylar or condylar neck fractures with medial or lateral displacement can be treated using an intraoral approach with satisfactory results with the advantages of the absence of visible scarring, the avoidance of facial nerve injury, and the ability to obtain rapid access to the fracture. (C) 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

Simvastatin Does Not Reduce Chemokine Production in Obesity Without Comorbidities

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Capacidade de suporte de carga de Latossolo Vermelho cultivado com cana-de-açúcar e efeitos da mecanização no solo

The objective of this work was to determine the load support capacity (LSC) of an Oxisol and, through compressibility models, relate it to wheel-soil interactions under management systems with one and three sugarcane crop cycles, with mechanized harvest. LSC evaluations were carried out on undisturbed soil samples, collected at planting row and bed, in four layers: 0.00-0.10, 0.10-0.20, 0.20-0.30, and 0.300.40 m. The contact area between wheels and soil was determined in order to estimate the contact pressure by agricultural machinery on the soil. Pre-consolidation pressures were used to determine LSC. The system with three cycles showed higher LSC than the system with only one cycle. The load support capacity of the soil evaluated in the range of friability is greater than the contact pressures applied to the soil by the wheels of the studied agricultural machines.

Qualidade ambiental dos fragmentos florestais na Bacia Hidrográfica do Rio Jundiaí-Mirim entre 1972 e 2013

The location of Jundiai-Mirim river basin, close to large urban centers and industrial parks, has contributed to the appreciation of their lands. Consequently, the region has an intense process of urbanization that resulted in an increasing environmental disturbance in the forest areas. Given the need to preserve existing natural vegetation, because the watershed is the source of water used to supply Jundiai, SP, this study evaluated changes in the environmental quality of the watershed forest fragments between 1972 and 2013. The environment quality was determined by evaluating nine indicators of environmental disturbance, obtained by techniques of Geoprocessing and integrated by Multicriteria Analysis. The results showed a constant tendency of deteriorating the environmental quality of natural vegetation between 1972 and 2013, attributed to the intense process of occupation of the watershed. It is concluded that: (a) urbanization and deforestation of natural vegetation were primarily responsible for changes in environmental quality; (b) there is a need to create public policies to preserve the natural vegetation in the watershed.

Systemic lupus erythematous and clinical outcomes in peritoneal dialysis

Background: The prevalence of systemic lupus erythematous (SLE) patients requiring renal replacement therapy (RRT) is increasing but data on clinical outcomes are scarce. Interestingly, data on technique failure and peritoneal-dialysis (PD)-related infections are rarer, despite SLE patients being considered at high risk for infections. The aim of our study is to compare clinical outcomes of SLE patients on PD in a large PD cohort. Methods: We conducted a nationwide prospective observational study from the BRAZPD II cohort. For this study we identified all patients on PD for greater than 90 days. Within that subset, all those with SLE as primary renal disease were matched with PD patients without SLE for comparison of clinical outcomes, namely: patient mortality, technique survival and time to first peritonitis, then were analyzed taking into account the presence of competing risks. Results: Out of a total of 9907 patients, we identified 102 SLE patients incident in PD and with more than 90 days on PD. After matching the groups consisted of 92 patients with SLE and 340 matched controls. Mean age was 46.9 +/- 16.8 years, 77.3% were females and 58.1% were Caucasians. After adjustments SLE sub-hazard distribution ratio for mortality was 1.06 (CI 95% 0.55-2.05), for technique failure was 1.01 (CI 95% 0.54-1.91) and for time to first peritonitis episode was 1.40 (CI 95% 0.92-2.11). The probability for occurrence of competing risks in all three outcomes was similar between groups. Conclusion: PD therapy was shown to be a safe and equally successful therapy for SLE patients compared to matched non-SLE patients.

Icodextrin reduces insulin resistance in non-diabetic patients undergoing automated peritoneal dialysis: results of a randomized controlled trial (STARCH)

Insulin resistance is a common risk factor in chronic kidney disease patients contributing to the high cardiovascular burden, even in the absence of diabetes. Glucose-based peritoneal dialysis (PD) solutions are thought to intensify insulin resistance due to the continuous glucose absorption from the peritoneal cavity. The aim of our study was to analyse the effect of the substitution of glucose for icodextrin on insulin resistance in non-diabetic PD patients in a multicentric randomized clinical trial. This was a multicenter, open-label study with balanced randomization (1:1) and two parallel-groups. Inclusion criteria were non-diabetic adult patients on automated peritoneal dialysis (APD) for at least 3 months on therapy prior to randomization. Patients assigned to the intervention group were treated with 2L of icodextrin 7.5%, and the control group with glucose 2.5% during the long dwell and, at night in the cycler, with a prescription of standard glucose-based PD solution only in both groups. The primary end-point was the change in insulin resistance measured by homeostatic model assessment (HOMA) index at 90 days. Sixty patients were included in the intervention (n = 33) or the control (n = 27) groups. There was no difference between groups at baseline. After adjustment for pre-intervention HOMA index levels, the group treated with icodextrin had the lower post-intervention levels at 90 days in both intention to treat [1.49 (95% CI: 1.23-1.74) versus 1.89 (95% CI: 1.62-2.17)], (F = 4.643, P = 0.03, partial η(2) = 0.078); and the treated analysis [1.47 (95% CI: 1.01-1.84) versus 2.18 (95% CI: 1.81-2.55)], (F = 7.488, P = 0.01, partial η(2) = 0.195). The substitution of glucose for icodextrin for the long dwell improved insulin resistance measured by HOMA index in non-diabetic APD patients.

Cone-beam evaluation of pharyngeal airway space in class I, II, and III patients

The purpose of this study is to make a 3-dimensional (3-D) evaluation of the pharyngeal airway space (PAS) in patients with class I, II, and III malocclusion. Sixty patients were evaluated. The patients were divided in 3 groups according to their occlusion classification. The volume and area of PAS were evaluated using the software Dolphin 3-D Imaging in the preoperative period for orthognathic surgery. PAS volume and area were influenced by different patterns of malocclusion. The mean volume and area for class III patients were statistically bigger than for classes I and II patients (P < .001). There was also a significant difference for volume values between class I and II patients, being the bigger volume for the class I patients (P < .05). It was possible to conclude that the class III patients presented a bigger PAS compared with classes I and II patients.

Automated peritoneal dialysis is associated with better survival rates compared to continuous ambulatory peritoneal dialysis: a propensity score matching analysis

The impact of peritoneal dialysis modality on patient survival and peritonitis rates is not fully understood, and no large-scale randomized clinical trial (RCT) is available. In the absence of a RCT, the use of an advanced matching procedure to reduce selection bias in large cohort studies may be the best approach. The aim of this study is to compare automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) according to peritonitis risk, technique failure and patient survival in a large nation-wide PD cohort. This is a prospective cohort study that included all incident PD patients with at least 90 days of PD recruited in the BRAZPD study. All patients who were treated exclusively with either APD or CAPD were matched for 15 different covariates using a propensity score calculated with the nearest neighbor method. Clinical outcomes analyzed were overall mortality, technique failure and time to first peritonitis. For all analysis we also adjusted the curves for the presence of competing risks with the Fine and Gray analysis. After the matching procedure, 2,890 patients were included in the analysis (1,445 in each group). Baseline characteristics were similar for all covariates including: age, diabetes, BMI, Center-experience, coronary artery disease, cancer, literacy, hypertension, race, previous HD, gender, pre-dialysis care, family income, peripheral artery disease and year of starting PD. Mortality rate was higher in CAPD patients (SHR1.44 CI95%1.21-1.71) compared to APD, but no difference was observed for technique failure (SHR0.83 CI95%0.69-1.02) nor for time till the first peritonitis episode (SHR0.96 CI95%0.93-1.11). In the first large PD cohort study with groups balanced for several covariates using propensity score matching, PD modality was not associated with differences in neither time to first peritonitis nor in technique failure. Nevertheless, patient survival was significantly better in APD patients.

É, não sou: ensaios sobre os afro-sambas no tempo e no espaço

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Linfoma de Hodgkin: características anátomo-clínicas e análise de novo biomarcador (IMP3)

Pós-graduação em Patologia - FMB

Expansão rápida de maxila assistida cirurgicamente por meio da piezocirurgia: relato de caso

Aim: the purpose of this study is to present a case of surgically assisted rapid maxillary expansion using piezosurgery and describe the benefits of using this device in this type of procedure. Case description: patient had adento-skeletal deformity Cl III with asevereatresia of jaw and underwent a rapid maxillary expansion and surgically assisted with the use of piezosurgery. Conclusion: the piezosurgerycan be used as an alternative in oral and maxillofacial surgery wich features provide greater accuracy and safety in surgery.

Influência das não linearidades geométricas em sistemas de suspensão com amortecimento assimétrico sob excitação harmônica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O desenvolvimento da memória na educação infantil: contribuições da Psicologia histórico-cultural para o ensino de crianças de 4 e 5 anos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da ingestão de nutrientes, segundo padrão alimentar de idosos do município de Botucatu - SP

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Expansão rápida de maxila assistida cirurgicamente por meio da piezocirurgia: relato de caso

Aim: the purpose of this study is to present a case of surgically assisted rapid maxillary expansion using piezosurgery and describe the benefits of using this device in this type of procedure. Case description: patient had adento-skeletal deformity Cl III with asevereatresia of jaw and underwent a rapid maxillary expansion and surgically assisted with the use of piezosurgery. Conclusion: the piezosurgerycan be used as an alternative in oral and maxillofacial surgery wich features provide greater accuracy and safety in surgery