Factores determinantes na definição da estratégia de uma companhia aérea

Considerando a gestão estratégica como um meio de alcançar uma performance superior face aos seus competidores, torna-se, então, necessário identificar as fontes de rentabilidade para o negócio, para formular e implementar uma estratégia que delas retire os maiores proveitos. A análise estratégica proporciona um conjunto de conceitos, modelos e técnicas de avaliação, que permitem aos gestores tomarem decisões mais adequadas às necessidades percebidas. Na realidade as transformações sucessivas verificadas no ambiente competitivo e a um ritmo cada vez mais crescente colocam às empresas a exigência de responder apropriadamente ao mercado, de forma a garantirem a sustentabilidade e o sucesso da sua actividade. Esta conjuntura não é estranha à indústria do turismo, que tem assistido à emergência de novos modelos de negócio, à mudança das preferências dos consumidores, ao incremento da tecnologia e, em alguns sectores, à desregulamentação, com implicações directas ao nível da gestão. O presente trabalho de investigação centra o seu estudo na fase de formulação da estratégia, particularizando para o sector de transporte aéreo, pretendendo reconhecer os elementos intervenientes no sector de transporte aéreo, perceber as relações de interdependência estabelecidas entre estes e identificar, classificar e compreender os factores relevantes para as decisões estratégicas. Analisa-se o problema da identificação dos factores determinantes na definição da estratégia de uma companhia aérea, procurando verificar se estes são de ordem económica, política, tecnológica e sócio-demográfica ou se por outro lado são de natureza dos destinos turísticos. Para tal, recorreu-se à revisão bibliográfica sobre o estado da arte, dando enquadramento teórico ao presente estudo, à elaboração e análise de entrevistas realizadas aos dirigentes das companhias aéreas portuguesas a operar para a Madeira, que permitiram adquirir um maior conhecimento da visão da indústria. Deste processo proveio que as empresas pertencentes ao sector de transporte aéreo, à semelhança das empresas de outros sectores, consideram que a estratégia assume um papel determinante para o sucesso da sua actividade, pelo facto das companhias aéreas desenvolverem a sua acção no longo prazo e necessitarem da análise periódica de elementos com influência no seu negócio. Conclui-se que os factores determinantes na definição da estratégia de uma companhia aérea são de ordem económica, política, tecnológica e sócio-demográfica, porquanto são os elementos que darão sustentabilidade às transportadoras de aceder ao destino.

A utilização de varões de GFRP nas estruturas de betão armado

A crescente preocupação com a deterioração e consequente reparação e reabilitação das estruturas de betão armado tradicionais, sobretudo devido ao fenómeno da corrosão associada aos varões de aço, que afecta significativamente a durabilidade deste tipo de estruturas, tem impulsionado a introdução dos varões de GFRP na área da engenharia civil. A progressiva utilização dos varões de GFRP, nas estruturas de betão armado, surge não só no sentido de colmatar as deficiências apresentadas pelo aço convencional, mas igualmente, pelas características que lhe são inerentes, das quais se destacam, entre outras, a elevada resistência à tracção e à fadiga, a elevada resistência química, a sua não condutividade electromagnética e corrosibilidade nula e o seu baixo peso próprio. Contudo, o comportamento frágil consequente do reduzido módulo de elasticidade, o custo início elevado e a falta de códigos de dimensionamento, têm tardado a sua aplicação generalizada. Neste contexto, procede-se no presente documento à elaboração de um Estado da Arte, com intuito de analisar o ponto de situação dos conhecimentos, seguida da apresentação da filosofia de dimensionamento e da descrição das propriedades físicas e mecânicas dos varões de GFRP. No sentido de avaliar o Estado Limite Último (E.L.U.) e o Estado Limite de Serviço (E.L.S.), dos elementos de betão armado com GFRP, realiza-se uma exposição dos modelos de dimensionamento sugeridos pelo ACI 440.1R-06 [3], pelo Fib-Bulletin 40 [21] e pelo ISIS Manual No.3 [25]. Por fim, dimensiona-se três elementos estruturais de betão armado com GFRP, com o objectivo de delinear as principais diferenças entre as armaduras de aço e de GFRP. Os exemplos de aplicação efectuados permitiram concluir, que de facto, o E.L.S. é maioritariamente condicionante neste tipo de estruturas, devido ao reduzido módulo de elasticidade, que afecta significativamente a deformação.

Modelação e estudo paramétrico do comportamento de vigas de betão armado com Varões de GFRP

A introdução de um novo material para a execução de estruturas, implica um amplo estudo sobre o mesmo, para que seja aceite como um material de utilização, ou solução, corrente na engenharia civil. Os varões plásticos reforçados com fibra de vidro, GFRP,apresentam-se com diversas vantagens para uma solução de substituição das tradicionais armaduras de aço no betão armado. Um Estado da Arte foi apurado para determinar o ponto de situação do conhecimento e dos estudos realizados por vários autores, desde o início das pesquisas até aos mais recentes estudos disponíveis. Neste seguimento, o presente estudo incide na análise do comportamento à flexão de vigas contínuas de betão armado com varões de GFRP, submetidas a um carregamento distribuído. O trabalho realiza-se com base em 18 modelos de elementos finitos para uma análise paramétrica, sendo os parâmetros estudados, o vão, a percentagem de armadura de flexão e a esbelteza da secção. Para validação do modelo foram, modeladas 7 vigas reais ensaiadas no âmbito de trabalhos de investigação de dois autores Os resultados das modelações das análises paramétricas foram comparados com uma análise elástica e uma análise plástica, utilizando a metodologia do ACI 440.1R-06, para a carga última de dimensionamento. Outras comparações foram feitas através dos limites de deformação do EN 1992-1-1, 2004. Analisa-se a distribuição de esforços, não elásticos, devido à perda de rigidez da viga. Os modelos das vigas mais esbeltas e com menor percentagem de armadura mostraram maior concordância com a análise realizada. As deformações comparadas com o limite L/250 mostram concordância de resultados.

Projeto e gestão de redes de transmissão e sistemas auxiliares

Neste relatório de estágio, entregue para obtenção do grau de mestre, é elaborado um sistema de registo e tratamento de alarmes em paralelo com a especificação e implementação de um sistema protótipo de recolha de alarmes em armários exteriores, para otimização da gestão da rede da Portugal Telecom (PT). O início do projeto agrupa o contato com as tecnologias de transmissão e alarmística da rede através do estado da arte e estudo dos equipamentos existentes, sobretudo Synchronous Digital Hierarchy (SDH) no que concerne aos débitos, à interligação de tecnologias, à sua monitorização e configuração. É indicado, ao longo do procedimento prático, o trabalho elaborado para a concentração dos dados do departamento numa única plataforma, disponibilizada aos utilizadores, a qual também é capaz de realizar um cruzamento dos alarmes da rede com os padrões encontrados para a ocorrência de determinados alarmes. O módulo implementado para a recolha de alarmes, que satisfaz um dos problemas de adaptação de estruturas remodeladas, é igualmente descrito, atendendo às necessidades de implementação e requisitos impostos pela empresa. O estudo das estruturas núcleo existentes, o acompanhamento do projeto de monitorização de alarmes de uma área de agregação de serviços e o desenvolvimento do trabalho são realizados através do gabinete de projeto e gestão de rede do departamento de operações da Madeira. Os resultados favorecem a Portugal Telecom em termos de atualização da sua estrutura de monitorização de alarmes, aumento da eficiência de resolução de problemas e optimização da gestão de recursos humanos.

Sistema sensor em fibra ótica para deteção de gás

O presente trabalho descreve duas técnicas de deteção de gás baseadas em fibra ótica e apresenta dois sistemas sensores testados em ambiente laboratorial, usando técnicas de processamento de sinal usualmente associadas à espetroscopia de absorção. O estudo inicial do estado da arte dos sensores baseados em fibra ótica para a deteção de gases apresenta soluções com elevada seletividade, sensibilidade e resolução que permitem tempos de resposta curtos e esquemas de multiplexagem versáteis. A técnica de espetroscopia de absorção direta (DAS) permite a deteção de gases de forma simples e com alguma eficácia, mas com uma baixa relação-sinal-ruido. A espetroscopia por modulação de comprimento de onda (WMS) é uma técnica muito eficaz e de elevada sensibilidade para a deteção de gases, dado que a deteção é deslocada para frequências afastadas do ruído base, melhorando significativamente a relação-sinal-ruído. Estas técnicas foram escolhidas para a implementação de dois sistemas optoeletrónicos, totalmente controlados pelas respetivas aplicações em LabVIEW para a deteção e monitorização de amónia (NH3), dióxido de carbono (CO2) e metano (CH4). O trabalho é finalizado com a caraterização laboratorial dos sistemas e avaliação do desempenho, permitindo a otimização dos sistemas e técnicas implementados. De referir que o trabalho realizado nas instalações da Unidade de Optoeletrónica e Sistemas Eletrónicos (UOSE) do Instituto de Engenharia de Sistemas e Computadores (INESC), Tecnologia e Ciência (TEC), laboratório associado coordenado pelo INESC Porto, permitiu, excelentes condições de trabalho, essenciais para implementar de forma prática os diversos conceitos estudados, bem como testar e caraterizar todos os sistemas desenvolvidos em ambiente laboratorial. O trabalho desenvolvido enquadra-se no âmbito do projeto europeu ECOAL-MGT (Gestão ecológica de pilhas de resíduos de carvão), que será implementado para monitorização remota de parâmetros fundamentais de uma escombreira de carvão em auto-combustão em S.ºPedro da Cova, Portugal.

Qualidade de vida no trabalho da Emater-RN: validação de um instrumento síntese de pesquisa e diagnóstico

The theoretical recital of the present study it is initiated of the evidence that the work occupies an important space in the man s life in way that the majority of the people works and passes great part of its time inside organizati ons. However, it is verified that the relation between man and work is becoming increasingly disagreement a time that the employees had started to complain work s routines, stress, not use all their potential and inadequate work s conditions. It can be observed by the way of Dejours (1994) studies. Thus, as contribution for the quality of work life s (QWL) studies the research developed here objectified to characterize the public employees quality of work life at EMATER -RN taking as reference an instrumen t of research synthesized from the typical academic literature of the subject. The synthesis of an ampler instrument is a necessity not taken care to the literature that treats on the subject but already perceived by some studies like Moraes et al (1990); Rodrigues (1989); Siqueira & Coleta (1989); Moraes et al (1992); Carvalho & Souza (2003); El -Aouar & Souza (2003) and Mourão, Kilimnick & Fernandes (2005); Adorno, Marques & Borges (2005) amongst others. These studies point out weak points of the existing models in the QWL s literature, as well as they recommend the elaboration of a model more flexible, that contemplates Brazilian cultural characteristics, and that contemplates the entire variable studied in the main existing models. For reach this objectiv e the adopted methodology was characterized as a case study with collected data in qualitative and quantitative way. Questionnaires and comments had been used as sources of evidences. These evidences had been tabulated through of statistical package SPSS ( Statistical Package for Social Science), in which the main technique of multivariate analysis used were the factorial analysis. As for the gotten results, it was verified the grouping of the quality of work life s indicators in 11 factors which are: Work s execution, Individual accomplishment, Work s equity, Relation individual and organization, Work s organization, Adequacy of the remuneration, Relation between head and subordinate, Effectiveness of the communication and the learning, Relation between work and personal life, Participation and Effectiveness of the work processes. Whatever to the characterization of the EMATER -RN s quality of work life it was clearly that to the measure that the satisfaction s evaluation with the QWL in the organization walks to intrinsic factors for extrinsic factors this level of satisfaction goes diminishing what points to the importance to improve these extrinsic factors in the institution. In summary it is possible to conclude that the organization studied has offered a significant set of referring variable to the quality of work life of the individual

Bibliotecas digitais em Arquitetura e urbanismo: um estudo sobre a arquitetura da informação digital

The goal of this paper was to search the state of the art from the Digital Libraries in Architecture and Urbanism in the Higher Education Institutions (IES) through conceptualizations and showing the importance of Digital Libraries in the disclosure and easing of information transferring. Questions about digital information architecture, usability, digital preservation and accessibility were approached. The research was made in the websites of Brazilian Universities, firstly to identify the institutions which offered the Architecture and Urbanism course, focusing on postgraduate education. After identifying the offering, the research was done by analyzing the contents, storage and dissemination and access to information, these libraries. It was found that the digital libraries are increasingly and taking part of organizations and educational institutions focusing on the knowledge dissemination releasing digitally information that may be needed for institution or the individual. A monitoring was done over of the physical and computational restructuring of the Board of Studies and Research in Architecture and Urbanism (Câmara de Estudos e Pesquisa em Arquitetura e Urbanismo, CEPAU), from the Architecture and Urbanism Course of the Federal University of Rio Grande do Norte (UFRN), showing the need of installing a Digital Library to integrate the databases of PPGAU s research groups, which today remain independent, with no interface among themselves. The research chosen area was Architecture and Urbanism, because there is a gap and little documentation about digital libraries in this area

Otimização e análise mecânica de pastas geopoliméricas para uso em poços sujeitos à injeção cíclica de vapor

Oil wells subjected to cyclic steam injection present important challenges for the development of well cementing systems, mainly due to tensile stresses caused by thermal gradients during its useful life. Cement sheath failures in wells using conventional high compressive strength systems lead to the use of cement systems that are more flexible and/or ductile, with emphasis on Portland cement systems with latex addition. Recent research efforts have presented geopolymeric systems as alternatives. These cementing systems are based on alkaline activation of amorphous aluminosilicates such as metakaolin or fly ash and display advantageous properties such as high compressive strength, fast setting and thermal stability. Basic geopolymeric formulations can be found in the literature, which meet basic oil industry specifications such as rheology, compressive strength and thickening time. In this work, new geopolymeric formulations were developed, based on metakaolin, potassium silicate, potassium hydroxide, silica fume and mineral fiber, using the state of the art in chemical composition, mixture modeling and additivation to optimize the most relevant properties for oil well cementing. Starting from molar ratios considered ideal in the literature (SiO2/Al2O3 = 3.8 e K2O/Al2O3 = 1.0), a study of dry mixtures was performed,based on the compressive packing model, resulting in an optimal volume of 6% for the added solid material. This material (silica fume and mineral fiber) works both as an additional silica source (in the case of silica fume) and as mechanical reinforcement, especially in the case of mineral fiber, which incremented the tensile strength. The first triaxial mechanical study of this class of materials was performed. For comparison, a mechanical study of conventional latex-based cementing systems was also carried out. Regardless of differences in the failure mode (brittle for geopolymers, ductile for latex-based systems), the superior uniaxial compressive strength (37 MPa for the geopolymeric slurry P5 versus 18 MPa for the conventional slurry P2), similar triaxial behavior (friction angle 21° for P5 and P2) and lower stifness (in the elastic region 5.1 GPa for P5 versus 6.8 GPa for P2) of the geopolymeric systems allowed them to withstand a similar amount of mechanical energy (155 kJ/m3 for P5 versus 208 kJ/m3 for P2), noting that geopolymers work in the elastic regime, without the microcracking present in the case of latex-based systems. Therefore, the geopolymers studied on this work must be designed for application in the elastic region to avoid brittle failure. Finally, the tensile strength of geopolymers is originally poor (1.3 MPa for the geopolymeric slurry P3) due to its brittle structure. However, after additivation with mineral fiber, the tensile strength became equivalent to that of latex-based systems (2.3 MPa for P5 and 2.1 MPa for P2). The technical viability of conventional and proposed formulations was evaluated for the whole well life, including stresses due to cyclic steam injection. This analysis was performed using finite element-based simulation software. It was verified that conventional slurries are viable up to 204ºF (400ºC) and geopolymeric slurries are viable above 500ºF (260ºC)

Desenvolvimento de um modelo de gestão do conhecimento para a melhoria do processo de desenvolvimento de produtos

The knowledge management has received major attention from product designers because many of the activities within this process have to be creative and, therefore, they depend basically on the knowledge of the people who are involved in the process. Moreover, Product Development Process (PDP) is one of the activities in which knowledge management manifests in the most critical form once it had the intense application of the knowledge. As a consequence, this thesis analyzes the knowledge management aiming to improve the PDP and it also proposes a theoretical model of knowledge management. This model uses five steps (creation, maintenance, dissemination, utilization and discard) through the verification of the occurrence of four types of knowledge conversion (socialization, externalization, combination and internalization) that it will improve the knowledge management in this process. The intellectual capital in Small and Medium Enterprises (SMEs) managed efficiently and with the participation of all employees has become the mechanism of the creation and transference processes of knowledge, supporting and, consequently, improving the PDP. The expected results are an effective and efficient application of the proposed model for the creation of the knowledge base within an organization (organizational memory) aiming a better performance of the PDP. In this way, it was carried out an extensive analysis of the knowledge management (instrument of qualitative and subjective evaluation) within the Design department of a Brazilian company (SEBRAE/RN). This analysis aimed to know the state-of-the-art of the Design department regarding the use of knowledge management. This step was important in order to evaluate in the level of the evolution of the department related to the practical use of knowledge management before implementing the proposed theoretical model and its methodology. At the end of this work, based on the results of the diagnosis, a knowledge management system is suggested to facilitate the knowledge sharing within the organization, in order words, the Design department

Qualidade em serviços de saúde: uma contribuição à definição de um modelo paramétrico e padrão de qualidade do tempo agendado para consulta ambulatorial

The knowledge management has received major attention from product designers because many of the activities within this process have to be creative and, therefore, they depend basically on the knowledge of the people who are involved in the process. Moreover, Product Development Process (PDP) is one of the activities in which knowledge management manifests in the most critical form once it had the intense application of the knowledge. As a consequence, this thesis analyzes the knowledge management aiming to improve the PDP and it also proposes a theoretical model of knowledge management. This model uses five steps (creation, maintenance, dissemination, utilization and discard) through the verification of the occurrence of four types of knowledge conversion (socialization, externalization, combination and internalization) that it will improve the knowledge management in this process. The intellectual capital in Small and Medium Enterprises (SMEs) managed efficiently and with the participation of all employees has become the mechanism of the creation and transference processes of knowledge, supporting and, consequently, improving the PDP. The expected results are an effective and efficient application of the proposed model for the creation of the knowledge base within an organization (organizational memory) aiming a better performance of the PDP. In this way, it was carried out an extensive analysis of the knowledge management (instrument of qualitative and subjective evaluation) within the Design department of a Brazilian company (SEBRAE/RN). This analysis aimed to know the state-of-the-art of the Design department regarding the use of knowledge management. This step was important in order to evaluate in the level of the evolution of the department related to the practical use of knowledge management before implementing the proposed theoretical model and its methodology. At the end of this work, based on the results of the diagnosis, a knowledge management system is suggested to facilitate the knowledge sharing within the organization, in order words, the Design department

Uma contribuição ao estudo das categorias internas e de sua proliferação em redes ARTMAP

ART networks present some advantages: online learning; convergence in a few epochs of training; incremental learning, etc. Even though, some problems exist, such as: categories proliferation, sensitivity to the presentation order of training patterns, the choice of a good vigilance parameter, etc. Among the problems, the most important is the category proliferation that is probably the most critical. This problem makes the network create too many categories, consuming resources to store unnecessarily a large number of categories, impacting negatively or even making the processing time unfeasible, without contributing to the quality of the representation problem, i. e., in many cases, the excessive amount of categories generated by ART networks makes the quality of generation inferior to the one it could reach. Another factor that leads to the category proliferation of ART networks is the difficulty of approximating regions that have non-rectangular geometry, causing a generalization inferior to the one obtained by other methods of classification. From the observation of these problems, three methodologies were proposed, being two of them focused on using a most flexible geometry than the one used by traditional ART networks, which minimize the problem of categories proliferation. The third methodology minimizes the problem of the presentation order of training patterns. To validate these new approaches, many tests were performed, where these results demonstrate that these new methodologies can improve the quality of generalization for ART networks

Perspectivas de inserção da energia solar fotovoltaica na geração de energia elétrica no Rio Grande do Norte

The generation of electricity in Brazil is predominantly renewable, with internal hydraulic generation being more than 70% of its energy matrix. The electricity rationing occurred in 2001 due to lack of rain, led the country to increase the participation of alternative energy sources. This need for new sources of energy makes the regional potential to be exploited, which configures the change of generation model from centralized generation to distributed generation. Among the alternative sources of energy, the solar energy is presented as very promising for Brazil, given that most of its territory is located near to the equator line, which implies days with greater number of hours of solar radiation. The state of Rio Grande do Norte (RN) has one of the highest levels of solar irradiation of the Brazilian territory, making it eligible to receive investments for the installation of photovoltaic solar plants. This thesis will present the state-of-the-art in solar photovoltaic power generation and will examine the potential for generation of solar photovoltaic power in Brazil and RN, based on solarimetrics measurements conducted by various institutions and also measurements performed in Natal, the state capital

Utilização de um secador solar para desintoxicação da torta de mamona

It´s been motivating motivated by the current rulers as an energy solution the use of the biodiesel as source of energy, that doesn't damage the environment and promotes the development of the areas where the base plant are grown. The process of production of the biodiesel, starting from the castor oil plant and its derivers, generates a known product as castor oil plant pie that has been used as fertilizer. Once disintoxicated, it can serve as animal ration, because it contains high content of proteins, presenting larger joined value. The disintoxication process, can be obtained through the process of drying the pie with the construction and use of models of dryers capable to elevate the temperature of the castor oil plant pie to approximately 60ºC.In this temperature the product tends to eliminate the ricina, with the aid of an aqueous solution of hydroxide of calcium, or still reach higher temperatures to make the disintoxication without a chemical treatment. It was made a bibliographical research about known processes of disintoxication of the castor oil plant pie from the autoclave use to the drying direct exposure to the sun. Starting from the state of the art and identification of the object, it was chosen solar dryers to eliminate the ricina. It was applied two types of solar dryers: the one of solar direct exposure, and the one with concentrador. The castor oil plant pie was separated in samples, with measurement of its initial mass, codified and placed in the dryers. The results were presented in graphs and tables forms, with the values of temperatures noticed. It was noticed the variations of temperature and the relationships analyzed related with the ricina content eliminated from the pie. The analysis of the ricina content was accomplished by Embrapa - Campina Grande, by eletroforese method. The analysis of the result of considering the content of ricina of the samples. It was observed that, we obtained lower rate of ricina in samples that had larger drying time and average value temperature above 60ºC. Comparing with the ones submitted to higher temperatures and in a shorter period of time. It was possible to evaluate the efficiency of the dryers in the desintoxication process of the samples, as well as the type of more appropriate dryer for the drying pie process. Finally, it was concluded that the solar dryer with concentrador presents higher values temperatures than the direct exposure one. So, it´s being more opportune applied in the castor oil plant pie drying process. However, more than one hour for drying time is needed

Estudo da influência de compostos recalcitrantes na remoção de matéria orgânica biodegradável no tratamento de efluente de refinarias de petróleo

Petroleum Refinery wastewaters (PRW) have hart-to-degrade compounds, such as: phenols, ammonia, cyanides, sulfides, oils and greases and the mono and polynuclear aromatic hydrocarbons: benzene, toluene and xylene (BTX), acenaphthene, nitrobenzene and naphtalene. It is known that the microrganisms activity can be reduced in the presence of certain substances, adversely affecting the biological process of wastewater treatment. This research was instigated due the small number of studies regarding to this specific topic in the avaiable literature. This body of work ims to evaluate the effect of toxic substances on the biodegradability of the organic material found in PRW. Glucose was chosen as the model substrate due to its biodegradable nature. This study was divided into three parts: i) a survey of recalcitants compounds and the removal of phenol by using both biological and photochemical-biological processes; ii) biomass aclimation and iii) evaluation of the inhibitory effect certain compounds have on glucose biodegradation. The phenol degradation experiments were carried out in an activity sludge system and in a photochemical reactor. The results showed the photochemical-biological process to be more effective on phenol degradation, suggesting the superioruty of a combined photochemical-biological treatment when compared with a simple biological process for phenol removal from industry wastewaters. For the acclimation step, was used an activated sludge from industrial wastewaters. A rapid biomass aclimation to a synthetic solution composed of the main inhibitory compouns fpund in a PRW was obtained using the following operation condition: (pH = 7,0; DO ≥ 2,0 mg/L; RS = 20 days e qH = 31,2 and 20,4 hours), The last part was consisted of using respirometry evaluation toxicity effects of selected compounds over oxygen uptake rate to adaptated and non adaptated biomass in the presence of inhibitory compounds. The adaptated sludge showed greater degration capacity, with lower sensibility to toxic effects. The respirometry has proved to be very practical, as the techiniques used were simple and rapid, such as: Chemical Oxygen Demand (COD), Dissolved Oxygen (DO), and Volatile Suspended Solids (VSS). Using the latter it is possible to perform sludge selection to beggingthe process; thus allowing its use for aerobic treatment system`s behacior prediction

Resolução espacial da Grade Ionosférica e do Give

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)