Letter to S.D. Woodruff regarding a resolution passed that the engineer be requested to examine the fence built by the contractors alongside of the Henry Vandenburgh Farm

Letter to S.D. Woodruff regarding a resolution passed that the engineer be requested to examine the fence built by the contractors alongside of the Henry Vandenburgh Farm and report to the secretary as to whether this is a lawful fence, completed according to Williams’ contract. This is signed by Duncan McFarland, president. There is a reply written by S.D. Woodruff at the bottom of the letter stating that the fence is not built in accordance with the contract, Dec. 18, 1856.

Mirroring Enzymes: The Role of H-Bonding In HQuin-BAM Catalyzed Asymmetric Aza-Henry Reactions: A DFT Study into the Reactivity, Mechanism, and Origins of Selectivity

The exact mechanistic understanding of various organocatalytic systems in asymmetric reactions such as Henry and aza-Henry transformations is important for developing and designing new synthetic organocatalysts. The focus of this dissertation will be on the use of density functional theory (DFT) for studying the asymmetric aza-Henry reaction. The first part of the thesis is a detailed mechanistic investigation of a poorly understood chiral bis(amidine) (BAM) Brønsted acid catalyzed aza-Henry reaction between nitromethane and N-Boc phenylaldimine. The catalyst, in addition to acting as a Brønsted base, serves to simultaneously activate both the electrophile and the nucleophile through dual H-bonding during C-C bond formation and is thus essential for both reaction rate and selectivity. Analysis of the H-bonding interactions revealed that there was a strong preference for the formation of a homonuclear positive charge-assisted H-bond, which in turn governed the relative orientation of substrate binding. Attracted by this well-defined mechanistic investigation, the other important aspect of my PhD research addressed a detailed theoretical analysis accounting for the observed selectivity in diastereoselective versions of this reaction. A detailed inspection of the stereodetermining C-C bond forming transition states for monoalkylated nitronate addition to a range of electronically different aldimines, revealed that the origins of stereoselectivity were controlled by a delicate balance of different factors such as steric, orbital interactions, and the extent of distortion in the catalyst and substrates. The structural analysis of different substituted transition states established an interesting dependency on matching the shape and size of the catalyst (host molecule) and substrates (guest molecules) upon binding, both being key factors governing selectivity, in essence, offering an analogy to positive cooperative binding effect of catalytic enzymes and substrates in Nature. In addition, both intra-molecular (intra-host) and inter-molecular (host-guest, guest-guest) stabilizing interactions play a key role to the high π-facial selectivity. The application of dispersion-corrected functionals (i.e., ωB97X-D and B3LYP-D3) was essential for accurately modeling these stabilizing interactions, indicating the importance of dispersion effects in enantioselectivity. As a brief prelude to more extensive future studies, the influence of a triflate counterion on both reactivity and selectivity in this reaction was also addressed.

Time on marsh lands for the months of January, February, March and April for Fred Holmes, Joseph Simpson, Duncan Davidson, Rose Osborne, Henry Wilson and William Baird

Time on marsh lands for the months of January, February, March and April for Fred Holmes, Joseph Simpson, Duncan Davidson, Rose Osborne, Henry Wilson and William Baird. This is signed by Fred Holmes, April 28, 1857.

Engineering services in marsh lands drainage for the months of January, February, March and April for Fred Holmes, Joseph Simpson, D. Davidson, Rose Osborne, Henry Wilson and William Baird

Engineering services in marsh lands drainage for the months of January, February, March and April for Fred Holmes, Joseph Simpson, D. Davidson, Rose Osborne, Henry Wilson and William Baird. This is signed by S.D. Woodruff, May 1, 1857.

Letter to C. Sauble [?] from Henry Miller [?]

Letter to C. Sauble [?] from Henry Miller [?] regarding mortgages, n.d.

Indenture of bargain and sale between Henry and Mary Miller of the Town of Niagara to Joseph Augustus Woodruff of the Town of Niagara

Indenture of bargain and sale between Henry and Mary Miller of the Town of Niagara to Joseph Augustus Woodruff of the Town of Niagara for 50 acres in the east half of Lot no. 15 in the 1st Concession in the Township of Southwold in Elgin County, April 2, 1853.

Discharge of Mortgage signed by Henry Kalar, President of the Niagara Permanent Building Society

Discharge of Mortgage signed by Henry Kalar, President of the Niagara Permanent Building Society stating that John McNeilly [?] has satisfied all money due and the mortgage is therefore discharged. The right hand side of this document is burned. Text is slightly affected, Aug. 8, 1853.

Letter to W.D. Woodruff from Henry E. Ahern of United States Trust Company of New York

Letter to W.D. Woodruff from Henry E. Ahern of United States Trust Company of New York (1 page, printed) which was sent with a cheque for $2,106 in trust for his account. This is accompanied by an envelope addressed to the trust company, a balance sheet and a receipt, July 14, 1908.

Letter to W.D. Woodruff from Henry E. Ahern of United States Trust Company of New York

Letter to W.D. Woodruff from Henry E. Ahern of United States Trust Company of New York (1 page, printed) which was sent with a cheque for $560.63 in trust for his account. This is accompanied by an envelope addressed to Mr. Woodruff, a balance sheet and a receipt, Oct.10, 1908.

Letter to Mrs. Maria DeV. Haynes from Henry Ahern of the United States Trust Company of New York

Letter to Mrs. Maria DeV. Haynes from Henry Ahern of the United States Trust Company of New York (1 page, printed) stating that the funding of bonds has been paid, Jan. 4, 1909.

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York (1 page, printed) stating that the funding of bonds has been paid. This is accompanied by an envelope addressed to Mr. Woodruff, a balance sheet and a receipt, Jan. 4, 1909.

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York (1 page, printed) which was sent with a cheque for $2,925. This is accompanied by an envelope addressed to the trust company, a balance sheet and a receipt, Jan. 11, 1909.

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York (1 page, printed) which was sent with a cheque for $410.41. This is accompanied by an envelope addressed to the trust company, a balance sheet and a receipt, Jan. 21, 1909.

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York

Letter to Mr. W. D. Woodruff from Henry Ahern of the United States Trust Company of New York (1 page, printed) which was sent with a cheque for $2223. This is accompanied by an envelope addressed to Mr. Woodruff, a balance sheet, Jul. 9, 1909.

Letter to Mr. W.D. Woodruff from Henry Ahern of the United States Trust Company of New York

Letter to Mr. W.D. Woodruff from Henry Ahern of the United States Trust Company of New York (1 page, printed) which was sent with a cheque for $433.38. This is accompanied by an envelope addressed to Mr. Woodruff, a balance sheet and 2 receipts, Apr. 6, 1910.