Eleanor Holmes Norton at City Hall for Intro 475

General note: Title and date provided by Bettye Lane.

Formulación de estrategias de mitigación y compensación de emisiones de gases efecto invernadero de Norton rose fulbright a partir del cálculo de la huella de carbono

Bogotá (Colombia) : Universidad de La Salle. Facultad de Ingeniería. Programa de Ingeniería Ambiental y Sanitaria

Ihanteena orjuuteen perustuva kristillinen yhteiskunta – Uskonnollinen ja yhteiskunnallinen orjuuden ja etelävaltioiden puolustus baptistipastori Ebenezer W. Warrenin romaanissa Nellie Norton

Yhdysvalloissa kehittyi noin vuosina 1850–1865 erityinen orjuutta puolustamaan noussut kaunokirjallisuuden lajityyppi. Sen synty oli osa etelävaltioiden elämäntavan ja siihen keskeisesti liittyneen orjuuden taakse organisoitunutta puolustautumista, joka kehittyi erityisesti kolmena Yhdysvaltojen sisällissotaa edeltäneenä vuosikymmenenä, jolloin etelän orjajärjestelmä joutui kovan arvostelun kohteeksi. Orjuuden puolustajien kirjoittama romaanikirjallisuus voidaan nähdä eräänlaisena etelän vastareaktiona Harriet Beecher Stowen suuren suosion saaneelle orjuutta kritisoineelle romaanille Setä Tuomon tupa, joka julkaistiin vuonna 1852. Keskityn tutkielmassani yhteen tämän orjuutta puolustaneen romaanikirjallisuuden edustajaan, baptistipastori Ebenezer W. Warrenin vuonna 1864 julkaisemaan romaaniin Nellie Norton: or Southern Slavery and the Bible. A scriptural refutation of the principal arguments upon which the abolitionists rely. A vindication of southern slavery from the old and new testaments. Romaani sijoittuu julkaisuajankohtansa puolesta lajityyppinsä viimeisimpien edustajien joukkoon. Tutkielmassani tarkastellaan, minkälaisista argumenteista romaanin keinoin esitetty orjuuden puolustus koostuu. Tämän lisäksi tarkastelen myös sitä, millainen kuva romaanissa annetaan etelävaltioiden, ja toisaalta niiden vastapuolena näyttäytyvien pohjoisten osavaltioiden ja Englannin elämäntavasta ja maailmankuvasta. Tutkielmani osoittaa orjuuden puolustuksen rakentuvan Warrenin romaanissa erityisesti uskonnollisista, rasistisista sekä yhteiskunnallisista argumenteista. Romaanissa luodaan näiden kautta voimakas vastakkainasettelu etelän orjayhteiskunnan ja pohjoisen ja Englannin vapaaseen työvoimaan perustuneiden teollistuneiden yhteiskuntien välille. Etelän kirjaimelliset ja konservatiiviset tulkinnat Raamatusta ja sen asemasta moraalin ja yhteiskuntajärjestyksen ylimpänä määrittelijänä asetetaan abolitionistien harhaoppisiksi esitettyjen liberaalimpien ja modernimpien raamatuntulkintojen vastakohdaksi. Vastaavasti etelän orjuuteen perustuvan yhteiskunnan rakenteet ja instituutiot esitetään raamatullisina ja hyveellisinä, siinä missä vapaaseen työvoimaan perustuneet yhteiskunnat esitetään moraalittomina ja raadollisina. Romaanista välittyy erityisesti kuva konservatiivisesta maailmasta, jossa uskonnolliset ja rasistiset ajattelumallit ovat keskeisessä asemassa pyrittäessä puolustamaan ja ylläpitämään orjuuteen perustuvaa eteläistä elämäntapaa.

Melhoria das Ações de Prevenção e Controle do Câncer de Colo Uterino e do Câncer de Mama na UBS Norton Vitorino Bohen, Acrelândia/AC

Resumo KIM, Alfredo Felix Gonzalez. Melhoria das Ações de Prevenção e Controle do Câncer de Colo Uterino e do Câncer de Mama na UBS Norton Vitorino Bohen, Acrelândia/AC. 2015. 67f. Trabalho de Conclusão de Curso (Curso de Especialização em Saúde da Família) - Departamento de Medicina Social, Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, 2015. O câncer de colo do útero apresenta-se como a segunda neoplasia maligna mais comum entre as mulheres no mundo e o de mama a terceira causa. No Brasil, as taxas de morbimortalidade por esses cânceres continuam elevadas, muito provavelmente porque as doenças ainda são diagnosticadas em estágios avançados. Ações de prevenção primária e detecção precoce de doenças são estratégias capazes de reduzir a morbimortalidade, de aumentar as chances de cura e melhorar a qualidade de vida. O controle dos cânceres do colo de útero e da mama depende de uma atenção básica qualificada e organizada, integrada com os demais níveis de atenção. Para tanto, realizou-se uma intervenção em 12 semanas, com o objetivo de melhorar o programa de prevenção e controle de câncer de colo uterino e de mama na Unidade Básica de Saúde Norton Vitorino Bohen, em Acrelândia, Estado do Acre. As metas planejadas consistiram em avaliar a cobertura das ações, a qualidade, a adesão das mulheres, o registro de informações, a avaliação de risco e a promoção de saúde. Os resultados foram longe do desejado, com baixas coberturas das ações às mulheres de 25 a 59 anos, o exame preventivo do câncer do útero alcançou 183 (20,7%) mulheres de 885 e de 50 a 69 anos com mamografias em dia foram quatro (1,9%) mulheres de 210, 180 (98,4%) mulheres com amostras satisfatórias do exame citopatológico. Entretanto, 67 (75,3%) mulheres tiveram avaliação dos sinais de alerta para o câncer de mama. A qualidade das coletas citopatológicas foi boa, 180 amostras de coleta citopatológicas foram satisfatórias (98,4%), a adesão das mulheres à realização de exame citopatológico de colo de útero e mamografia e a promoção de saúde foram importantes. Com a intervenção a equipe adquiriu conhecimento do protocolo da prevenção e controle de câncer de colo uterino e câncer de mama, envolveu-se mais em qualquer instância do processo assistencial e foram mais conscientes da importância de sua atuação e da necessidade de aliarem o conhecimento técnico específico ao compromisso com um resultado satisfatório da atenção, levando o significado desse resultado para cada mulher. Palavras-chave: atenção primária à saúde; saúde da família; saúde da mulher; programas de rastreamento; neoplasias do colo do útero; neoplasias da mama.

Associação da medroxiprogesterona ao protocolo Ovsynch para inseminação artificial em tempo fixo de búfalas cíclicas (Bubalus bubalis) criadas na Amazônia Oriental

O presente estudo visou avaliar os efeitos da associação da medroxiprogesterona (análogo sintético da progesterona) ao protocolo Ovsynch sobre o crescimento folicular, a ovulação e a taxa de concepção de búfalas criadas na Amazônia Oriental (Tracuateua-PA). Vinte e sete fêmeas adultas (G1 n=14 e G2 n=13), cíclicas, sem bezerro ao pé e com ECC 3,5 foram submetidas a Ovsynch. Os animais do G2 receberam 60 mg de medroxiprogesterona entre D0 e D7 (D0=início do tratamento). A ultra-sonografia ovariana foi realizada nos D 0, 7, 9 e 10. O contingente de folículos pequenos diferiu no D7 (G1: 4,57±0,60 versus G2: 6,54±0,67; P=0,05). Tempo e tratamento influenciaram o diâmetro folicular no D7. O crescimento do folículo dominante entre D7 e D9 foi maior nos animais tratados (G1: 2,05±0,49 mm/dia versus 3,48±0,41 mm/dia; P<0,05). Mais animais do G1 ovularam precocemente (35,71% versus 30,77%), porém isso não afetou as taxas de concepção (G1: 50,00% e G2: 30,77%; P>0,05). Os achados sugerem que a medroxiprogesterona (1) aumenta recrutamento folicular e retarda o crescimento dos folículos com diâmetro maior que 5,0 mm entre D0 e D7; (2) sua retirada incrementa em 1,7 vezes o crescimento folicular do D7 ao D9; (3) pode contribuir para a ovulação de folículos maiores e, em tese, para maior formação de tecido luteínico; (4) não promove ovulação precoce após o Ovsynch; (5) não eleva as taxas de concepção após sincronização de fêmeas cíclicas e com bom escore corporal, devendo ser avaliada para uso em fêmeas acíclicas ou com ECC mais baixo.

Predictive Validity of Waterlow Scale for Pressure Ulcer Development Risk in Hospitalized Patients

AIM: We sought to evaluate the predictive validity of the Waterlow Scale in hospitalized patients. SUBJECTS AND SETTING: The study was conducted at a general private hospital with 220 beds and a mean time of hospitalization of 7.4 days and a mean occupation rate of approximately 80%. Adult patients with a Braden Scale score of 18 or less and a Waterlow Scale score of 16 or more were studied. The sample consisted of 98 patients with a mean age of 71.1 +/- 15.5 years. METHODS: Skin assessment and scoring by using the Waterlow and Braden scales were completed on alternate days. Patients were examined at least 3 times to be considered for analysis. The data were submitted to sensitivity and specificity analysis by using receiver operating characteristic (ROC) curves and positive (+LR) and negative (-LR) likelihood ratios. RESULTS: The cutoff scores were 17, 20, and 20 in the first, second, and third assessment, respectively. Sensitivity was 71.4%, 85.7%, and 85.7% and specificity was 67.0%, 40.7%, and 32.9%, respectively. Analysis of the area under the ROC curve revealed good accuracy (0.64, 95% confidence interval [CI]: 0.35-0.93) only for the cutoff score 17 in the first assessment. The results also showed probabilities of 14%, 10%, and 9% for the development of pressure ulcer when the test results were positive (+LR) and of 3% (-LR) when the test results were negative for the cutoff scores in the first, second, and third assessment, respectively. CONCLUSION: The Waterlow Scale achieved good predictive validity in predicting pressure ulcer in hospitalized patients when a cutoff score of 17 was used in the first assessment.

Equivalence between hot tensile and creep testing data for Kanthal A1 alloy

Hot tensile and creep tests were carried out on Kanthal A1 alloy in the temperature range from 600 to 800 degrees C. Each of these sets of data were analyzed separately according to their own methodologies, but an attempt was made to find a correlation between them. A new criterion proposed for converting hot tensile data to creep data, makes possible the analysis of the two kinds of results according to usual creep relations like: Norton, Monkman-Grant, Larson-Miller and others. The remarkable compatibility verified between both sets of data by this procedure strongly suggests that hot tensile data can be converted to creep data and vice-versa for Kanthal A1 alloy, as verified previously for other metallic materials.

Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus

The solution structure of robustoxin, the lethal neurotoxin from the Sydney funnel-web spider Atrax robustus, has been determined from 2D H-1 NMR data, Robustoxin is a polypeptide of 42 residues cross-linked by four disulphide bonds, the connectivities of which were determined from NMR data and trial structure calculations to be 1-15, 8-20, 14-31 and 16-42 (a 1-4/2-6/3-7/5-8 pattern), The structure consists of a small three-stranded, anti-parallel beta-sheet and a series of interlocking gamma-turns at the C-terminus. It also contains a cystine knot, thus placing it in the inhibitor cystine knot motif family of structures, which includes the omega-conotoxins and a number of plant and animal toxins and protease inhibitors. Robustoxin contains three distinct charged patches on its surface, and an extended loop that includes several aromatic and non-polar residues, Both of these structural features may play a role in its binding to the voltage-gated sodium channel. (C) 1997 Federation of European Biochemical Societies.

The Australian public's perception of genetically-engineered foods

This paper describes a recent Australian survey on attitudes to genetically-engineered foods. Initial results of the survey are discussed and presented in tabular form. While there is some acceptance of particular genetically-engineered products, the results show that responfdents did have concerns over the long-term health effects of eating genetically-engineered foods and the potential risk to the environment. Respondents clearly endorsed labelling of the products and government control of the technology.

Some factors affecting white stem borer Scirpophaga innotata (Walker) (Lepidoptera : Pyralidae) injury to rice

The amount of injury to rice caused by white stem borer Sciryophaga innotata depends on cultivar, and stage of plant and insect development, as well as insect abundance. Of the cultivars tested, IR64, IR42, Cisadane and Ketan. IR64 were the most susceptible and Ketan the least susceptible to feeding damage. Third and fourth instars consumed more stem dry matter than other stages, although yield reduction depended on the number of tillers injured. On the wider stemmed Ketan, fewer tillers were injured than the narrower IR64. Larvae are more likely to move among tillers in the third instar stage, which tends to coincide with maximum tillering and may result in more tillers injured and in yield reduction. Later instar larvae burrow downwards to the internode where they pupate. Larvae appear to move less among tillers in 'resistant' cultivars. Management strategies should target this pest at third instar and when its abundance in the field warrants control. Fewer than 10% of the neonates establish successfully on stems, and this mortality needs to be taken into account when deciding on control, as does the ability of rice plants to compensate for injury. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

The sound-field characterisation of a power transformer

In order to effectively suppress the noise radiation from large electrical power transformers, both the structure-borne and air-borne sound fields need to be characterised. The characterisation can be made either from theoretical predictions or by in-situ measurements. This paper presents the study of the sound radiation from a large power transformer in a substation. The radiation pattern can be predicted from the measured acceleration distribution and the predicted value is not affected by other noise sources. Alternatively, the farfield sound pressure level can be predicted from the sound pressure level measured at NEMA locations. Both the near- and far-field power radiation can be in-situ measured using the sound intensity technique. It is shown that both the vibration of a transformer tank wall and the radiated noise consist of a series of tonal components mainly at the first few harmonic frequencies of 100 Hz. Also, the neglect of the noise radiation from the transformer (top and bottom) lids does not affects the accuracy of the transformer radiation characterisation. (C) 1998 Elsevier Science Ltd. All rights reserved.

Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor

Two synthetic analogues of murine epidermal. growth factor, [Abu6, 20] mEGF4-48 (where Abu denotes amino-butyric acid) and [G1, M3, K21, H40] mEGF1-48, have been investigated by NMR spectroscopy. [Abu6, 20] mEGF4-48 was designed to determine the contribution of the 6-20 disulfide bridge to the structure and function of mEGF The overall structure of this analogue was similar to that of native mEGF, indicating that the loss of the 6-20 disulfide bridge did not affect the global fold of the molecule. Significant structural differences were observed near the N-terminus, however, with the direction of the polypeptide chain between residues four and nine being altered such that these residues were now located on the opposite face of the main beta-sheet from their position in native mEGF Thermal denaturation experiments also showed that the structure of [Abu6, 20] mEGF4-48 was less stable than that of mEGF. Removal of this disulfide bridge resulted in a significant loss of both mitogenic activity in Balb/c 3T3 cells and receptor binding on A431 cells compared with native mEGF and mEGF4-48, implying that the structural changes in [Abu6, 20] mEGF4-48, although limited to the N-terminus, were sufficient to interfere with receptor binding. The loss of binding affinity probably arose mainly from steric interactions of the dislocated N-terminal region with part of the receptor binding surface of EGF [G1, M3, K21, H40] mEGF1-48 was also synthesized in order to compare the synthetic polypeptide with the corresponding product of recombinant expression. Its mitogenic activity in Balb/c 3T3 cells was similar to that of native mEGF and analysis of its H-1 chemical shifts suggested that its structure was also very similar to native.

A comparison of lipid variables as predictors of cardiovascular disease in the Asia Pacific Region

PURPOSE: Many guidelines advocate measurement of total or low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), and triglycerides (TG) to determine treatment recommendations for preventing coronary heart disease (CHD) and cardiovascular disease (CVD). This analysis is a comparison of lipid variables as predictors of cardiovascular disease. METHODS: Hazard ratios for coronary and cardiovascular deaths by fourths of total cholesterol (TC), LDL, HDL, TG, non-HDL, TC/HDL, and TG/HDL values, and for a one standard deviation change in these variables, were derived in an individual participant data meta-analysis of 32 cohort studies conducted in the Asia-Pacific region. The predictive value of each lipid variable was assessed using the likelihood ratio statistic. RESULTS: Adjusting for confounders and regression dilution, each lipid variable had a positive (negative for HDL) log-linear association with fatal CHD and CVD. Individuals in the highest fourth of each lipid variable had approximately twice the risk of CHD compared with those with lowest levels. TG and HDL were each better predictors of CHD and CVD risk compared with TC alone, with test statistics similar to TC/HDL and TG/HDL ratios. Calculated LDL was a relatively poor predictor. CONCLUSIONS: While LDL reduction remains the main target of intervention for lipid-lowering, these data support the potential use of TG or lipid ratios for CHD risk prediction. (c) 2005 Elsevier Inc. All rights reserved.