A estratégia de vendas, marketing e serviços (front office activities) de produtos de alta tecnologia na era do conhecimento

Trata das mudanças que já começaram a ocorrer no contexto empresarial e que regerão a nova economia do século xxi. Enfoca as novas exigência dos clientes, que se tornarão cada vez mais sofisticados e demandarão transformações nas atividades de front office. As empresas vencedoras estarão alicerçadas em três pilares principais: relacionamento de aprendizado com os clientes, liderança que promova a adaptação e recursos humanos autogerenciados.

Segurança das condições de aplicação de herbicidas com aerobarco em plantas daninhas aquáticas no lago da Hidrelétrica de Jupiá

Os objetivos deste trabalho foram quantificar as exposições dérmicas (EDs) e respiratórias (ERs) proporcionadas ao piloto e ao seu ajudante nas aplicações de herbicidas para o controle de plantas daninhas aquáticas com aerobarco; classificar essas condições de trabalho em seguras ou inseguras; e calcular a necessidade de controle das exposições (NCE) e o tempo de trabalho seguro (TTS). O aerobarco utilizado tinha casco de alumínio (4,85 x 2,42 m) e acionamento por hélice acoplada a motor a gasolina de 350 HP. O equipamento de pulverização era composto por bomba de diafragma com fluxo máximo de 49,69 L min-1, pressão máxima de 25 kg cm-2, acionada por motor a gasolina de 4 HP, e tanque de calda de 189 L. A barra de pulverização de alumínio era composta de duas seções laterais de 3 m, posicionadas na linha entre o encosto do banco do piloto e o início da estrutura protetora da hélice. Cada seção da barra tinha seis bicos com pontas de jato plano com indução de ar AI 100 03, espaçados de 0,5 m, e uma ponta OC 20 fixada em cada extremidade. O conjunto de pontas pulverizava faixas de 6 m de largura e aplicava o volume de calda de 200 L ha-1. O sistema tinha gerenciador de fluxo, controlado por central eletrônica acoplada a DGPS (com precisão submétrica), para corrigir automaticamente a vazão em função de alterações na velocidade real da embarcação. As EDs e ERs aos herbicidas foram calculadas com os dados substitutos das exposições às caldas, avaliadas com os traçadores cobre e manganês adicionados às caldas. As exposições foram extrapoladas para uma jornada de trabalho de seis horas. A segurança das condições de trabalho foi determinada com o cálculo da margem de segurança (MS), utilizando-se a fórmula MS = (NOEL x 70)/(QAE x 10), em que QAE = quantidade absorvível da exposição. As condições de trabalho foram classificadas em seguras, se MS>1, ou inseguras, se MS<1. As exposições proporcionadas pelas condições de trabalho foram de 10,65 mL de calda por dia para o piloto e de 16,80 mL por dia para o ajudante, que fica sentado em uma cadeira a 2,0 m à frente do piloto e da barra de pulverização. Classificaram-se como seguras as aplicações dos herbicidas glyphosate (Rodeo, 6 L ha-1), 2,4D (DMA 806 BR, 8 L ha-1) e fluridone (Sonar AQ, 0,4 L ha-1), para o piloto e o seu ajudante. Classificou-se como insegura a aplicação do herbicida diquat (Reward, 4,0 L ha-1) para as duas condições de trabalho, cujas necessidades de controle das exposições calculadas foram de 65% para o piloto e de 78% para o ajudante do piloto.

Perfil imuno-histoquímico do infiltrado inflamatório no front de invasão em carcicomas epidermóides de língua e lábio inferior

The progression of the oral squamous cells carcinomas (OSCCs) seems to suffer influence from related factors to the host, as local and systemic immunologic response, which are essential to the antineoplasic defenses. The purpose of this study was evaluate the local immunity in 30 tongue and 20 lower lip SCC by immunohistochemistry method, utilizing antibodies anti-CD3, CD4, -CD8, -CD25 e -ζ(zeta), which immunoexpressions were compared considering the anatomical localization, the intensity of the inflammatory infiltrate into the front of invasion and metastases. The CD4/CD8+ ratio was calculated for each case and associate with the mentioned variable, being the intensity of the inflammatory infiltrated also compared with the anatomical localization and metastase and for this the cases had been grouped in two categories: (n = 10) absent/scarce inflammatory infiltrate; and (n = 40) moderate/intense infiltrate. Fisher´s exact test was performed (α= 0.05) and it was not observed any significant correlation between these groups with anatomical sites and metastases. With regard to the immunoexpression, the CD3+, CD4+, CD8+ and CD25+ cells count was higher in the lower lip SCCs while the anti-ζimmunomarcation was more evident in the non metastatic cases. Through the statistical analyses, it was verified that the CD3 exhibited positive-significant correlation with the inflammatory infiltrate (p = 0.023). Furthermore, antibodies against CD8 and CD25 cells were also significantly correlated with the inflammatory infiltrate (p = 0.002 and 0.030, respectively) and with the anatomical site (p = 0.004 and p = 0.004) mainly in the lower lip SCCs. CD4/CD8 ratio did not show significant association with metastase nor with anatomical localization. We conclude that the inflammatory infiltrated of the Bryne s (1998) system did not constitute an indicator of aggressiveness in the tongue and lower lip SCCs analyzed and that clinical behavior of the SCCs studied was related in part to the immunohistochemical profile of infiltrated the inflammatory present in tumoral invasion front

Cortactin is associated with perineural invasion in the deep invasive front area of laryngeal carcinomas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Pion form factor in the light-front

The pion electromagnetic form factor is calculated with a light-front quark model. The plus and minus components of the electromagnetic current are used to calculate the electromagnetic form factor in the the Breit frame with two models for the q (q) over bar vertex. The light-front constituent quark model describes very well the hadronic wave functions for pseudo-scalar and vector particles. Symmetry problems arising in the light-front approcah are solved by the pole dislocation method. The results are compared with new experimental data and with other quark models.

Electromagnetic structure and weak decay of meson K in a light-front QCD-inspired model

The kaon electromagnetic (e.m.) form factor is reviewed considering a light-front constituent quark model. In this approach, it is discussed the relevance of the quark-antiquark pair terms for the full covariance of the e.m. current. It is also verified, by considering a QCD dynamical model, that a good agreement with experimental data can be obtained for the kaon weak decay constant once a probability of about 80% of the valence component is taken into account.

Quantizing a relativistic free-particle on the light front: some subtle aspects

We use the light-front machinery to study the behavior of a relativistic free particle and obtain the quantum commutation relations from the classical Poisson brackets. We argue that their usual projection onto the light-front coordinates from the covariant commutation relations show that there is an inconsistency in the expected correlation between canonically conjugate variables time x(+) and energy p(-). This incompatibility between canonical conjugate variables in the light front is discussed in the context of Poisson brackets and a suggestion is made on how to avoid it.

Pair term in the electromagnetic current within the Front-Form dynamics: spin-0 case

The frame and scale dependence of the pair-term contribution to the electromagnetic form factor of a spin-zero composite system of two-fermions is studied within the Light Front. The form factor is evaluated from the plus-component of the current in the Breit frame, using for the first time a nonconstant, symmetric ansatz for the Bethe-Salpeter amplitude. The frame dependence is analyzed by allowing a nonvanishing plus component of the momentum transfer, while the dynamical scale is set by the masses of the constituents and by mass and size of the composite system. A transverse momentum distribution, associated with the Bethe-Salpeter amplitude, is introduced which allows to define strongly and weakly relativistic systems. In particular, for strongly relativistic systems, the pair term vanishes for the Drell-Yan condition, while is dominant for momentum transfer along the light-front direction. For a weakly relativistic system, fitted to the deuteron scale, the pair term is negligible up to momentum transfers of 1 (GeV/c)(2). A comparison with results obtained within the Front-Form Hamiltonian dynamics with a fixed number of constituents is also presented. (C) 2002 Elsevier B.V. B.V. All rights reserved.