Politicas públicas para agricultura familiar: o caso do Programa de Aquisição de Alimentos (PAA) no estado de São Paulo, Brasil

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Avaliação Histológica e histomorfométrica do reparo ósseo em tíbias osteotomizadas de ratos (rattus novergicus albinus), submetidos a tratamento com ultrassom, frente à presença e ausência de carga

The response of bone metabolism is directly related to hormonal factors and mechanical stimuli that the bone is exposed. The ultrasonic energy on bone healing have been shown to be crucial for the stimulation and improvement in quality of newly formed tissue. The aim of this study was to analyze the action of low intensity ultrasound on bone healing of tibial osteotomy in rats subjected to tail suspension, through histological analysis and histomorphometry. Eighteen Rattus norvegicus albinos, Wistar, adults were divided into three groups, arranged as follows: G1 (n = 6), who remained free for a period of 15 days, G2 (n = 5), suspended by the tail for a period of 15 days and G3 (n = 7), suspended by the tail for a period of 36 days. In all three groups, both tibias were subjected to mono-cortical bone injury 4X2 mm in the medial region of the diaphysis, and the left limb was used as control and the right limb undergoing treatment with ultrasound (U.S.). The right tibia was treated with pulsed ultrasound at a frequency of 1.5 MHz, duty cycle 1:4, 30mW/cm2, for 12 sessions of 20 minutes each. Samples of tibia were subjected to histological analysis, blindly, with light microscopy and histomorphometric analysis by specific software Image-Pro 6.1. The average percentage of new bone formation were subjected to analysis of variance in subdivided parcels and multiple comparison test "Student-Newman-Keuls (SNK), with a significance level of 5%. The average values and standard deviations of the percentage of newly formed bone for the groups showed the least amount of bone repair G1t (13.62% ± 4.88%) - G1c (8.68% ± 4.16%) compared G2t groups (27.17% ± 11.36%) - G2c (10.10% ± 7.90%) and G3t (23.19% ± 5.61%) - G3c (15.74% ± 7 08%). However, the mean values and standard deviations of the percentage of newly formed bone repair in the tibia treated G2t and G3t were significantly higher when compared to the repair of tibia in the control group (G2c and G3c). Consequently, we conclude that ultrasound has helped to accelerate bone repair in both the presence and absence of cargo.

Laser terapêutico no reparo ósseo de ratos submetidos à ausência de carga

Low-intensity laser has been used as a physical agent in various fields of medical sciences such as bone and tissue repair. Meanwhile little is known about its effects in adverse conditions such as abolition of load and osteopenic. With the assumption that the laser Ga-Al-As accelerates the process of bone consolidation, goal of this study was to evaluate bone mineral density (BMD) in incomplete transverse osteotomies of tibia in adult rats, treated with low power laser therapy in three different groups: G1 (n = 10), reference 15 days; G2 (n=10), suspended by the tail and, accordingly, treated with laser for 12 days; G3 (n = 10), suspended by the tail by 36 days and that after 21 days, there was laser treatment for 12 days. The right tibia treated with laser and left served as control. The laser was used to Ga-Al-As, DMC - Flash Lase® III, with wavelength 830nm, 100 mW, 4J, 140 J / cm ², 40s of application in 12 sessions. It was used densitometer-Lunar DPX®, with computer program for "small animals", and the analysis of BMD was made in the bone throughout the region and the osteotomy. The results showed no efficacy of laser therapy in the process of bone repair, both in animals of group 1, as in group 2 and 3. It follows that either the low-power laser was not an effective performance or the effects of laser therapy is not only manifested at the site of irradiation as well as the systemic level.

Chá mate melhora a resistência à natação e reduz o dano oxidativo induzido pelo exercício em ratos submetidos à única sessão de natação

Several nutritional interventions are performed in order to reduce the impact of EO induced by exercise. Some studies suggest that mate tea (CM) have compounds, which can act as antioxidants reducing EO. The aim of this study was to evaluate the effect of CM induced under the EO after a single bout of aerobic exercise. Methods: We used male Wistar rats (50 days and 200g) distributed in four experimental groups: control (CON); mate tea (CM), Swimming (N); Swimming+mate tea (N + CM) . The CM and N+CM groups received CM diluted in distilled water at 96 ° C for five days, oropharyngeal route (50 mg / kg body weight, 0.5 mL). Both groups were adapted to the aquatic environment prior to experimental day, after a single swimming session, with 5% of body weight attached to the tail, until the animals reached exhaustion. Immediately after the state of exhaustion, peripheral blood was collected for further analysis. Results: The animals of the group N + CM showed improved resistance swimming compared to group C (p < 0.0001). No increase in lipid oxidative damage and production of lactate in group N + CM , compared to group N , may be attributed to the significant increase in plasma uric acid concentrations demonstrated in this study was observed . Conclusion: Therefore, the results indicate that consumption of CM may be natural strategy for improving aerobic exercise endurance and reduce the impact of EO induced by aerobic exercise.

Efeito de diferentes gomas de mascar sobre o pH salivar de crianças

Objective: To evaluate the effect of different chewing gum brands on the salivary pH of children with primary dentition. Method: Forty children were selected and assigned to four groups: control (no chewing gum); sugarless chewing gum; chewing gum with casein phosphopeptide-amorphous calcium phosphate; and chewing gum with xylitol. The first saliva collection was made after supervised tooth brushing for stabilization of the oral pH. Next, all children were instructed to drink slowly 100 mL of a cola-based soft drink (Coca-Cola®) and a new saliva collection was made 10 min later. Then, each group chewed on the chewing gum for 5 min and discarded it after this time. Saliva was collected again at 5, 10 and 15 min intervals after start using the chewing gum. Measurement of salivary pH was made with colorimetric test papers and a digital pH-meter. Data were analyzed statistically by analysis of variance and Tukey’s test at a 5% significance level. Results: The use of chewing gums accelerated the increase of salivary pH to considerably alkaline levels after consumption of an acidic beverage, especially within the first minutes. The highest levels were obtained in the groups of children that used chewing gums containing xylitol and casein phosphopeptide-amorphous calcium phosphate. Conclusion: Children that used the chewing gums after ingestion of an acidic soft drink presented an increase in salivary pH, with the best results in the groups that used chewing gums containing casein phosphopeptide-amorphous calcium phosphate and xylitol.

Spectrophotometric evaluation of color changes of esthetic brackets stored in potentially staining solutions

The purpose of this study was to evaluate, in vitro, the chromatic behavior of esthetic brackets stored in potentially staining solutions. The sample were divided into four groups according to the commercial brand and stored in four different solutions (distilled water, cola soda, coffee and mouthrinse) at 37°C for 14 days. Possible color changes measured according to the CIE L*a*b* color system with a spectrophotometer at five intervals of time after storage. The statistical analysis was carried out using ANOVA to 1%, Tukey's tests and decomposition of interactions with a significance level of 5%.The color changes were dependent on the solution, storage time and the brand of brackets. The largest color changes were observed in the G3, followed by G2, G1/G4. The esthetic brackets do not present satisfactory and stable chromatic behavior.

Diagnóstico e tratamento de mucocele em odontopediatria: relato de caso

Mucocele is a retention phenomenon from minor salivary gland caused by the excretory ducts rupture. This phenomenon may be caused by local trauma and its location is usually more frequent in the lower lip. Clinically, they appear as nodular lesions and may be exophytic and pedunculated. Histologically, this lesion can be classified as mucus extravasation phenomenon and mucus retention cyst. The treatments described in the literature are total lesion excision, marsupialization, cryosurgery, laser or micromarsupialização. To report a case of mucocele by mucus extravasation developed after a local trauma. A 7 years old Male was attended in the Pediatric Dentistry Clinic, Araçatuba School of Dentistry, complaining about the appearance of lesion in the lower lip since 40 days approximately. During clinical oral examination, it was observed that the lesion was pedunculated, nodular, fibrous to palpation, around 2 cm in diameter, similar in color to the surrounding mucosa, smoothly in surface, non-ulcerated and asymptomatic. As treatment, it was chosen the total lesion excision. Histopathology test confirmed the clinical diagnosis of: mucocele. Since mucocele is a frequent lesions in the oral cavity, it is extremely important that the professionals can to recognize this lesion (its pathogenesis and clinical features), to achieve a definitive diagnosis and perform an appropriate treatment.

Ciclamato de sódio em refrigerantes de baixa caloria

Sodium cyclamate contents in the widely consumed low calorie soft drinks were determined. Low calorie soft drinks made from cola, guarana, orange, lemon and grape were analyzed following the technique described by Sjörberg and Alanko (1987), with some modifications. The methodology recovery assays were carried out at three spiked levels, and the average recovery of 92.5% and 110.3% were found in cola and guarana, respectively; and the relative standard deviation was of 3.7%. The average sodium cyclamate contents ranged from 27.1 ± 1.1 (cola A) to 127.3 ± 1.5 mg.100 mL-1 (lemon B), indicating that the acceptable daily intake of the sweetener can be easily exceeded after drinking low calorie beverages. All of the analyzed low calorie soft drinks showed sodium cyclamate contents higher than those stated on the label, ranging from 12.9% (cola A) to 19.0% (lemon B). Among 18 low calorie soft drinks analyzed, only four showed the average sodium cyclamate contents in accordance with the maximum limit permitted by Brazilian legislation, that is 40 mg.100 mL-1 of beverage; and in other samples the sweetener exceeded ranging from 74.8% (orange) to 218.3% (lemon B) above of the limit permitted.

Análise do pré-mix de breu esterificado e policloreto de alumínio como agente de colagem interna em sistemas alcalinos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo do processo de reparo de enxerto ósseo em bloco submetido ao recobrimento com etil-cianoacrilato: análise histométrica e imunoistoquímica em ratos

Pós-graduação em Odontologia - FOA

Arcabouço tridimensional para células tronco, processo de obtenção do mesmo e seu uso

A presente invenção descreve um arcabouço (scaffold) tridimensional biodegradável de fibrina, formado por uma serinoprotease extraída a partir de veneno de serpente, um crioprecipitado rico em fibrinogênio extraído de bubalinos, o diluente cloreto de cálcio e uma solução de uma população de células tronco. O arcabouço é apropriado para suportar uma população de 106 células por mL de fibrina por um período prolongado de tempo, em que as células tronco são mesenquimais, de tecido umbilical e células tronco mononucleares. A invenção descreve, ainda, o processo de obtenção do arcabouço, cujos componentes são providos separadamente e polimerizam-se in situ após mistura. O arcabouço descrito apresenta inúmeras aplicações médicas, podendo aumentar a vascularização, a quimiotaxia celular, a regeneração nervosa e/ou a cicatrização de feridas no local da administração. Devido à sua origem animal, não há o risco de transmitir doenças infecciosas.

Geografia e imagem publicitária: um diálogo possível

The aim of present work is the interpretation of a Coca Cola soft drink advertising image that is shown on a billboard in the city of Presidente Prudente, in São Paulo state. The billboard shows a scene of the video titled Happiness Factory which was presented on television in 2008. Decoding this kind of image, which is integrated to the theoretical and methodical option, favors the visual perception of shapes and their meanings as a reading of the image and the inclusion of the studies of phenomenology of cultural geography to the social reality could reveal some other dimensions, such as the symbolic, the imaginary, the aesthetic ones.This fact will contribute to widen the social trait of Geography and it represents our object of study.The reading will be done after some reflexion on the function of an external advertisement, that is, within the urban context of Presidente Prudente when refering to billboard being studied. It will also be discussed the importance of becoming a critical reader when interpreting advertising messages presented by the communication means in general.

Nanopartículas lipídicas como sistemas carreadores para ivermectina e metopreno visando aplicações em veterinária

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Detecção de impressões digitais fraudulentas utilizando padrões mapeados localmente em multiescala

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Antiulcerogenic activity of the aqueous fraction of Anacardium humile St. Hil (Anacardiaceae)

Anacardium humile St. Hil. is being used in traditional medicine to treat ulcer. The present work evaluated the mechanisms of action involved in the anti-ulcer properties of the aqueous fraction from leaves of A. humile (AHQ). Gastroprotection of A. humile was evaluated in ethanol and piroxicam models. Mechanisms of action such as mucus production, nitric oxide (NO), sulfhydryl compounds (SH) and the anti-secretory action were evaluated. The acetic acid-induced gastric ulcer model was used to evaluate the A. humile healing properties. Results obtained in the ethanol model showed that AHQ provided significant gastroprotection at all the tested doses (50, 100, and 200 mg/kg). Thereby, the following protocols were performed using the dose capable of producing the most effective gastroprotection, which was the AHQ 200 mg/kg (P < 0.001). Moreover, AHQ (200 mg/kg) protected the mucosa from piroxicam-induced damage. Mucus, NO, and SH did not participate on this gastroprotection. AHQ interfere in H+ secretion in gastric mucosa, thus exerting an anti-secretory activity. Our results suggest that the gastroprotection and cicatrisation process executed by AHQ occurred due to its anti-secretory activity. This study reinforces its traditional medicinal use. Considering that the current therapies are based on the use of anti-secretory agents, the A. humile arises as a promising alternative antiulcer therapy.