828 resultados para CHRONIC DISEASES


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Gastric ulcer is an excoriated area of the gastric mucosa. It is among the predominant gastrointestinal chronic diseases. The essential oils represent an important part of the traditional pharmacopoeia in many countries and have been successfully used for gastroprotection and ulcer healing. Thus, this review presents the experimental activity of essential oils traditionally used in the gastric ulcer prevention and treatment, considering their families, part of the plant studied, bioassays, and their mechanisms of gastroprotection and ulcer healing, with the aim of stimulating novel studies in the search for a new phytomedicine to treat gastric diseases. © 2012 The Authors Fundamental and Clinical Pharmacology © 2012 Société Française de Pharmacologie et de Thérapeutique.

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Peanut is one of the few plants that synthesizes resveratrol, a phenolic compound of the stilbene class, which has been associated with reduced risk of developing chronic diseases, such as cancer, cardiovascular diseases, skin diseases, pulmonary diseases, diabetes and neurological diseases. Resveratrol was detected in different parts of the peanut plant, including roots, leaves, seeds and their derivatives. The wild species of the Arachis section are also strong candidates to synthesize resveratrol because they are phylogenetically closely related to cultivated peanut. Our objective was to characterize the resveratrol content in ten wild species of Arachis with three different genomes (A, B and K). The plant material was composed of leaves of the ten species treated (test) and not treated (control) with ultraviolet (UV) radiation. The test and control samples were extracted and the identification and quantification of resveratrol was performed using high performance liquid chromatography (HPLC). All species studied synthesized resveratrol and the concentrations ranged from 299.5 μg/g in A. kempff-mercadoi to 819.9 μg/g in A. cardenasii. DPPH antioxidant activity varied between 18.7 % for A. duranensis and 48.2 % in A. simpsonii. The results showed that wild Arachis species are a potential source of alleles for improvement of cultivated peanut, with the aim of achieving higher resveratrol content in leaves. © 2013 Springer Science+Business Media Dordrecht.

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Physical inactivity is associated with chronic diseases in older adults. There are different domains of physical activity, such as leisure and locomotion. This study investigate the associations between different domains of physical activity, comorbidities and aging in hypertensive adults. Participants included 192 hypertensive respondents classified in groups of active and insufficiently active for leisure-time, locomotion, occupation and total time. They were stratified in age groups. Waist circumference was measured and comorbidities were self-reported. The chi-square test analyzed these associations; a one-way ANOVA compared the age groups (significance at p <0.05). The mean total time and occupational physical activity were lower for groups ages over 60 and 70 years, respectively. Occupational activity was associated with age in the female group, and with cholesterol and diabetes in males, who also had physical activity of locomotion associated with waist circumference. Physical activity of hypertensive patients is associated with comorbidities in different age groups and sex.

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Background: The Stroke remains one of the major chronic diseases worldwide, and is considered a major cause of disability, which results not only in persistent neurological deficits, but also in the high physical deconditioning, nevertheless there are not many forms of assessing functional capacity in this population. We aimed to investigate the feasibility of the Six Minute Walk Teste and the Six-Minute Step Test (6MST) in post-stroke patients and compare the behavior of physiological variables during the 6MST and the Six-Minute Walk Test (6MWT), by correlating the functional performance obtained in both tests. Method. The 6MWT was carried out according to the American Thoracic Society (ATS) and the 6MST was performed in six minutes in order to compare it to the 6MWT in a 20 cm step. Was included post-stroke individuals able to walk without aid. All of them did the 6MWT and the 6MST. Results: 12 patients participated in the study. There was no statistical difference in the parameters analyzed when tests were compared. There was poor correlation between the functional performance in both tests. Conclusion: The 6MWT and the 6MST is feasible for post-stroke patients and physiological responses are equal during the performance of both tests. However, there was no correlation with respect to functional performance, which was assessed by the distance walked in the 6MWT and by the number of steps climbed in the 6MST. © 2013 da Silva et al.; licensee BioMed Central Ltd.

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Introduction: Technical literature shows high frequencies of injuries occurring in classical ballet dancers; however, only limited information about the permanent effects of chronic diseases are mentioned. Objective: To compare the presence of MSD among dancers who wear pointe shoes and those who do not. Methods: The research was conducted at the 27th Festival of Joinville in Santa Catarina. The study had the participation of 111 dancers, 88 of whom wore pointe shoes while 23 did not. Specific procedures were used to obtain information related to MSD and foot injuries caused by dancing. Results: The most affected parts were the knees (29.7% with pointe shoes versus 39% without), spine (26.4% with pointe shoes versus 22% without), and ankle/foot (20% with pointe shoes versus 12.2% without). Through odds ratio and respective confidence intervals (IC95%), the study identified protection factor in the knees (0.24; CI95% - 0.09-0.64) and legs (0.11; CI95% - 0.02-0.65) for dancers who wear pointe shoes. It was found that the risk of injuries in specific structures of the foot is significantly higher among those dancers. In this case, the appearance of bunions (9.74; CI95% - 1.25-75,99), calluses on the toes (3.46; CI95% - 1.29-9.27) and the association of the three (4.47; CI95% - 1.69-11.83) were those that showed an increased risk factor compared to dancers who do not stand en pointe. Conclusion: The use of pointe shoes in elite Brazilian dancers was associated to lower occurrence of MSD in the knee and leg, however it was strongly associated to foot injuries.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Biologia Geral e Aplicada - IBB

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Pós-graduação em Biociências e Biotecnologia Aplicadas à Farmácia - FCFAR

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Pós-graduação em Alimentos e Nutrição - FCFAR