New-England judged, by the spirit of the Lord. In two parts. First, containing a brief relation of the sufferings of the people call'd Quakers in New England, from the time of their first arrival there, in the year 1656, to the year 1660 ... In answer to the declaration of their persecutors apologizing for the same, MDCLIX. Second part, being a farther relation of the cruel and bloody sufferings of the people call'd Quakers in New-England, continued from anno 1660, to anno 1665. Beginning with the sufferings of William Leddra, whom they put to death.

Microfilm. Ann Arbor, Mich., University Microfilms [n.d.] (American culture series, Reel 498.8)

American Unitarianism : or, a brief history of "The progress and present state of the Unitarian churches in America" : compiled from documents and information communicated by the Rev. James Freeman, D. D. and William Wells, Jun. Esq. of Boston, and from other Unitarian gentlemen in this country /

Extracted from the author's "Memoirs of the life of the Reverend Theophilus Lindsey" printed in London, 1812, and now published for the benefit of the Christian churches in this country without note or alteration.

Family prayers : collected from the sacred scriptures, the book of common prayer, and the works of Bishop Wilson /

Mode of access: Internet.

Life of William M. Richardson, LL. D., late chief justice of the Superior court in New Hampshire ...

Mode of access: Internet.

Ancient geography, as connected with chronology, and preparatory to the study of ancient history; accompanied with an atlas. Compiled chiefly from D'Anville, Adam, Lavoisne, Malte Brun, and other standard works. To which are added problems on the globes, and rules for the construction of maps. To accompany the modern geography by William C. Woodbridge.

Bound with Woodbridge, W.C. A system of universal geography. Hartford 1835.

"In the matter of the investigation of advances in rates by carriers in official classification territory." Testimony of William C. Brown, president of the New York central lines. Washington, D.C., October 13th and 14th, 1910.

At head of title: Docket no.3400.

Of patience and submission to authority : a sermon preach'd before the Lord Mayor and the Court of Aldermen, at Guild-hall Chapel on the 27th of January, 1683/4 /

Signatures: A-H⁴.

History of the town of Waitsfield, Vermont, 1782-1908 : with family genealogies /

Includes index.

Contributions to medical and biological research, dedicated to Sir William Osler, bart., M.D., F.R.S., in honour of his seventieth birthday, June 12, 1919,

Paged continuously.

Nomination of William D. Ruckelshaus : hearings before the Committee on Environment and Public Works, United States Senate, Ninety-eighth Congress, first session, on the nomination of William D. Ruckelshaus, to be Administrator of the Environmental Protection Agency, May 3, 4, and 5, 1983.

Includes bibliographical references.

A memoir of the Right Hon. William Edward Hartpole Lecky, M.P., O.M., LL. D., D.C.L., LITT. D., member of the French Institute and of the British Academy,

Mode of access: Internet.

The works of William E. Channing, D. D.

Includes bibliographical references.

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

Cyclotides are a recently discovered class of proteins that have a characteristic head-to-tail cyclized backbone stabilized by a knotted arrangement of three disulfide bonds. They are exceptionally resistant to chemical, enzymatic and thermal treatments because of their unique structural scaffold. Cyclotides have a range of bio-activities, including uterotonic, anti-HIV, anti-bacterial and cytotoxic activity but their insecticidal properties suggest that their natural physiological role is in plant defense. They are genetically encoded as linear precursors and subsequently processed to produce mature cyclic peptides but the mechanism by which this occurs remains unknown. Currently most cyclotides are obtained via direct extraction from plants in the Rubiaceae and Violaceae families. To facilitate the screening of cyclotides for structure-activity studies and to exploit them in drug design or agricultural applications a convenient route for the synthesis of cyclotides is vital. In this review the current chemical, recombinant and biosynthetic routes to the production of cyclotides are discussed.