882 resultados para Amory family (Hugh Amory, b. 1605)


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Excerpts taken possibly from Mustamlī Bukhārī's commentary on al-Taʻarruf.

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Various Shiite devotional texts to be recited in religious assemblies (majālis) commemorating the events leading to the martyrdom of the Shii Imam Ḥusain b. ʻAlī (d. 680). Each majlis (there is twenty) begins with a synoptic heading. The beginning of 17th majlis suggests that some of these texts are based on Mahdī b. Ab Zarr al-Kāshānī an-Niraqī's "Muḥarriq al-qulub (a Shiite history of the martyrs of the Prophet's family).

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The NF-κB family member p65 is central to inflammation and immunity. The purpose of this study was to identify and characterize evolutionary conserved genes modulating p65 transcriptional activity. Using an RNAi screening approach, we identified chaperonin containing TCP1 subunit η (CCTη) as a regulator of Drosophila NF-κB proteins, Dorsal and Dorsal-related immunity factor (Dif). CCTη was also found to regulate NF-κB-driven transcription in mammalian cells, acting in a promoter-specific context, downstream of IκB kinase (IKK). CCTη knockdown repressed IκB and CXCL2/MIP2 transcription during the early phase of NF-κB activation while impairing the termination of CCL5/RANTES and CXCL10/IP10 transcription. The latter effect was associated with increased DNA binding and reduced p65 acetylation, presumably by altering the activity of histone acetyltransferase CREB-binding protein (CBP). We identified p65 lysines (K) 122 and 123 as target residues mediating the CCTη-driven termination of NF-κB-dependent transcription. We propose that CCTη regulates NF-κB activity in a manner that resolves inflammation.

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Includes index.

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Standing (Adults) L-R: Marion Waterhouse Angell (Mrs. J.R.); James Rowland Angell; Andrew C. McLaughlin; Fanny C. Cooley. Angell (Mrs. A.C.); Alexis Caswell Angell; Sarah Caswell Angell (daughter of A.C), Lois Angell McLaughlin

Middle Row: James Waterhouse Angell (son of J.R.), Marion Angell (McAlpin) (daughter of James R.) James Burrill Angell, Isabel McLaughlin

Front Row: Constance McLaughlin (Green); Robert Cooley Angell (son of A.C.); Esther Lois McLaughlin (Donahue) David Blair McLaughlin; Rowland Hazard McLaughlin; James Burrill Angell II (son of A.C.): James Angell McLaughlin

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Mode of access: Internet.

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Mode of access: Internet.

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Xerox reprint, 1962, by University Microfilms.