Audit report on the Shelby County Area Solid Waste Agency for the year ended June 30, 2009

Audit report on the Shelby County Area Solid Waste Agency for the year ended June 30, 2009

Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2009

Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2009

Audit report on the Hardin County Sanitary Solid Waste Disposal Commission for the year ended June 30, 2009

Audit report on the Hardin County Sanitary Solid Waste Disposal Commission for the year ended June 30, 2009

Audit report on the Rural Iowa Waste Management Association for the year ended June 30, 2009

Audit report on the Rural Iowa Waste Management Association for the year ended June 30, 2009

Audit report on the Wayne-Ringgold-Decatur County Solid Waste Management Commission for the year ended June 30, 2009

Audit report on the Wayne-Ringgold-Decatur County Solid Waste Management Commission for the year ended June 30, 2009

Audit report on the Jones County Solid Waste Management Commission for the year ended June 30, 2009

Audit report on the Jones County Solid Waste Management Commission for the year ended June 30, 2009

Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2009

Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2009

Audit report on the Crawford County Area Solid Waste Agency Commission for the year ended June 30, 2009

Audit report on the Crawford County Area Solid Waste Agency Commission for the year ended June 30, 2009

Audit report on the Delaware County Solid Waste Disposal Commission for the year ended June 30, 2009

Audit report on the Delaware County Solid Waste Disposal Commission for the year ended June 30, 2009

Audit report on the Great River Regional Waste Authority for the year ended June 30, 2009

Audit report on the Great River Regional Waste Authority for the year ended June 30, 2009

Muscle protein waste in tumor-bearing rats is effectively antagonized by a beta 2-adrenergic agonist (clenbuterol). Role of the ATP-ubiquitin-dependent proteolytic pathway.

Tissue protein hypercatabolism (TPH) is a most important feature in cancer cachexia, particularly with regard to the skeletal muscle. The rat ascites hepatoma Yoshida AH-130 is a very suitable model system for studying the mechanisms involved in the processes that lead to tissue depletion, since it induces in the host a rapid and progressive muscle waste mainly due to TPH (Tessitore, L., G. Bonelli, and F. M. Baccino. 1987. Biochem. J. 241:153-159). Detectable plasma levels of tumor necrosis factor-alpha associated with marked perturbations in the hormonal homeostasis have been shown to concur in forcing metabolism into a catabolic setting (Tessitore, L., P. Costelli, and F. M. Baccino. 1993. Br. J. Cancer. 67:15-23). The present study was directed to investigate if beta 2-adrenergic agonists, which are known to favor skeletal muscle hypertrophy, could effectively antagonize the enhanced muscle protein breakdown in this cancer cachexia model. One such agent, i.e., clenbuterol, indeed largely prevented skeletal muscle waste in AH-130-bearing rats by restoring protein degradative rates close to control values. This normalization of protein breakdown rates was achieved through a decrease of the hyperactivation of the ATP-ubiquitin-dependent proteolytic pathway, as previously demonstrated in our laboratory (Llovera, M., C. García-Martínez, N. Agell, M. Marzábal, F. J. López-Soriano, and J. M. Argilés. 1994. FEBS (Fed. Eur. Biochem. Soc.) Lett. 338:311-318). By contrast, the drug did not exert any measurable effect on various parenchymal organs, nor did it modify the plasma level of corticosterone and insulin, which were increased and decreased, respectively, in the tumor hosts. The present data give new insights into the mechanisms by which clenbuterol exerts its preventive effect on muscle protein waste and seem to warrant the implementation of experimental protocols involving the use of clenbuterol or alike drugs in the treatment of pathological states involving TPH, particularly in skeletal muscle and heart, such as in the present model of cancer cachexia.

Audit report on the Rathbun Area Solid Waste Commission for the year ended June 30, 2010

Audit report on the Rathbun Area Solid Waste Commission for the year ended June 30, 2010

Correction for heart rate variability during 3D whole heart MR coronary angiography.

PURPOSE: To evaluate the effect of a real-time adaptive trigger delay on image quality to correct for heart rate variability in 3D whole-heart coronary MR angiography (MRA). MATERIALS AND METHODS: Twelve healthy adults underwent 3D whole-heart coronary MRA with and without the use of an adaptive trigger delay. The moment of minimal coronary artery motion was visually determined on a high temporal resolution MRI. Throughout the scan performed without adaptive trigger delay, trigger delay was kept constant, whereas during the scan performed with adaptive trigger delay, trigger delay was continuously updated after each RR-interval using physiological modeling. Signal-to-noise, contrast-to-noise, vessel length, vessel sharpness, and subjective image quality were compared in a blinded manner. RESULTS: Vessel sharpness improved significantly for the middle segment of the right coronary artery (RCA) with the use of the adaptive trigger delay (52.3 +/- 7.1% versus 48.9 +/- 7.9%, P = 0.026). Subjective image quality was significantly better in the middle segments of the RCA and left anterior descending artery (LAD) when the scan was performed with adaptive trigger delay compared to constant trigger delay. CONCLUSION: Our results demonstrate that the use of an adaptive trigger delay to correct for heart rate variability improves image quality mainly in the middle segments of the RCA and LAD.

Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2010

Audit report on the Butler County Solid Waste Commission for the year ended June 30, 2010

Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2010

Audit report on the Pocahontas County Solid Waste Commission for the year ended June 30, 2010