957 resultados para proposal to state
Resumo:
This project develops a smartphone-based prototype system that supplements the 511 system to improve its dynamic traffic routing service to state highway users under non-recurrent congestion. This system will save considerable time to provide crucial traffic information and en-route assistance to travelers for them to avoid being trapped in traffic congestion due to accidents, work zones, hazards, or special events. It also creates a feedback loop between travelers and responsible agencies that enable the state to effectively collect, fuse, and analyze crowd-sourced data for next-gen transportation planning and management. This project can result in substantial economic savings (e.g. less traffic congestion, reduced fuel wastage and emissions) and safety benefits for the freight industry and society due to better dissemination of real-time traffic information by highway users. Such benefits will increase significantly in future with the expected increase in freight traffic on the network. The proposed system also has the flexibility to be integrated with various transportation management modules to assist state agencies to improve transportation services and daily operations.
Resumo:
This report documents work undertaken in the demonstration of a low-cost Automatic Weight and Classification System (AWACS). An AWACS procurement specification and details of the results of the project are also included. The intent of the project is to support and encourage transferring research knowledge to state and local agencies and manufacturers through field demonstrations. Presently available, Weigh-in-Motion and Classification Systems are typically too expensive to permit the wide deployment necessary to obtain representative vehicle data. Piezo electric technology has been used in the United Kingdom and Europe and is believed to be the basic element in a low-cost AWACS. Low-cost systems have been installed at two sites, one in Portland Cement Concrete (PCC) pavement in Iowa and the other in Asphaltic Cement Concrete (ACC) pavement in Minnesota to provide experience with both types of pavement. The systems provide axle weights, gross vehicle weight, axle spacing, vehicle classification, vehicle speed, vehicle count, and time of arrival. In addition, system self-calibration and a method to predict contact tire pressure is included in the system design. The study has shown that in the PCC pavement, the AWACS is capable of meeting the needs of state and federal highway agencies, producing accuracies comparable to many current commercial WIM devices. This is being achieved at a procurement cost of substantially less than currently available equipment. In the ACC pavement the accuracies were less than those observed in the PCC pavement which is concluded to result from a low pavement rigidity at this site. Further work is needed to assess the AWACS performance at a range of sites in ACC pavements.
Resumo:
The skin is privileged because several skin-derived stem cells (epithelial stem cells from epidermis and its appendages, mesenchymal stem cells from dermis and subcutis, melanocyte stem cells) can be efficiently captured for therapeutic use. Main indications remain the permanent coverage of extensive third degree burns and healing of chronic cutaneous wounds, but recent advances in gene therapy technology open the door to the treatment of disabling inherited skin diseases with genetically corrected keratinocyte stem cells. Therapeutic skin stem cells that were initially cultured in research or hospital laboratories must be produced according strict regulatory guidelines, which ensure patients and medical teams that the medicinal cell products are safe, of constant quality and manufactured according to state-of-the art technology. Nonetheless, it does not warrant clinical efficacy and permanent engraftment of autologous stem cells remains variable. There are many challenges ahead to improve efficacy among which to keep telomere-dependent senescence and telomere-independent senescence (clonal conversion) to a minimum in cell culture and to understand the cellular and molecular mechanisms implicated in engraftment. Finally, medicinal stem cells are expansive to produce and reimbursement of costs by health insurances is a major concern in many countries.
Resumo:
BACKGROUND: In Switzerland, 30% of HIV-infected individuals are diagnosed late. To optimize HIV testing, the Swiss Federal Office of Public Health (FOPH) updated 'Provider Induced Counseling and Testing' (PICT) recommendations in 2010. These permit doctors to test patients if HIV infection is suspected, without explicit consent or pre-test counseling; patients should nonetheless be informed that testing will be performed. We examined awareness of these updated recommendations among emergency department (ED) doctors. METHODS: We conducted a questionnaire-based survey among 167 ED doctors at five teaching hospitals in French-Speaking Switzerland between 1(st) May and 31(st) July 2011. For 25 clinical scenarios, participants had to state whether HIV testing was indicated or whether patient consent or pre-test counseling was required. We asked how many HIV tests participants had requested in the previous month, and whether they were aware of the FOPH testing recommendations. RESULTS: 144/167 doctors (88%) returned the questionnaire. Median postgraduate experience was 6.5 years (interquartile range [IQR] 3; 12). Mean percentage of correct answers was 59 ± 11%, senior doctors scoring higher (P=0.001). Lowest-scoring questions pertained to acute HIV infection and scenarios where patient consent was not required. Median number of test requests was 1 (IQR 0-2, range 0-10). Only 26/144 (18%) of participants were aware of the updated FOPH recommendations. Those aware had higher scores (P=0.001) but did not perform more HIV tests. CONCLUSIONS: Swiss ED doctors are not aware of the national HIV testing recommendations and rarely perform HIV tests. Improved recommendation dissemination and adherence is required if ED doctors are to contribute to earlier HIV diagnoses.
Resumo:
In the new book series 'ESASO Course Series', the essentials of the courses of the European School for Advanced Studies in Ophthalmology (ESASO) are made available to interested ophthalmologists, optometrists, technicians and residents all over the world. In this volume, the seminars on surgical retina presented by renowned experts during ESASO's activities are collected. Many specialists have contributed their knowledge to make this volume a device to give practical support. The topics range from prevention to state-of-the-art diagnostic techniques and the latest surgical treatment options for many eye conditions such as diabetic retinopathy and rhegmatogenous retinal detachment. This publication provides the ophthalmologist with the main aspects of surgical retina in a simple and practical update.
Resumo:
DAS/HRE publishes "Just the Facts" an almanac on the Executive Branch workforce. To assist state decision makers in preparing for the future. Thorough strategic planning is requisite to state government's future ability to provide quality products and services. The almanac is intended as an historical source of workforce date that can be used for comparative purposes as the workforce continues to change in Iowa.
Resumo:
Competine Creek is an 8,653 acre subwatershed of Whitebreast Creek which drains directly to Lake Red Rock. The Marion Soil and Water Conservation District has prioritized water quality protection efforts within Competine Creek subwatershed because 1) this watershed has been identified as a significant contributor of sediment, nutrients, and bacteria to Competine Creek and Lake Red Rock, 2) the watershed provides unique outreach opportunities due to its unique rural and urban interface, and 3) by using a targeted approach to address water quality, the likelihood of successfully demonstrating water quality improvements is high due to its manageable size. The specific goals of this proposal to WIRB (Phase I) are to: 1) reduce sediment and nutrient delivery by 1787 tons and 2144 lbs by installing conservation practices on high priority agricultural land; and 2) install urban conservation practices that reduce the volume of peak flow, improve streambank stability, and promote infiltration of stormwater runoff before it enters Competine Creek. The Marion SWCD has assembled a unique group of partners and secured funding from multiple sources to implement this project.
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The Watershed Planning Advisory Council (WPAC) was established by the Iowa Legislature (see Appendix A: Iowa Code 466B.31) to assemble a diverse group of stakeholders to make recommendations to state and federal agencies to protect water resources in Iowa. In 2015, WPAC prioritized the seven areas for recommendations outlined in 466B.31, and small work groups drafted recommendations for approval by the full membership.
Resumo:
Near Karnezeika a roughly 140 m thick Upper Cretaceous section consists of interbedded pelagic limestones, cherts and coarse polymict breccias including ophiolites and shallow water limestones. At the base, pink pelagic limestones rest on deeply altered and fractured Lower Jurassic Pantokrator Limestone. This first pelagic facies is dated as middle Turonian, based on planktonic Foraminifera. Over 100 m of coarse ophiolite-carbonate breccias, interpreted as a channel or canyon fill in a pelagic environment, document the erosion of the Late Jurassic nappe edifice along the Cretaceous Pelagonian margin. Above these breccias, we mesured 16 m of principally pink and red pelagic limestones and radiolarian cherts, in which we recovered well-preserved radiolarians discussed here. In this interval, the presence of planktonic Foraminfera allows to state a late Turonian to Coniacian age. More than 40 radiolarian species are described and figured in this work. The radiolarian chronostratigraphy established by 10 different authors in 11 publications was compared for this study and used to establish radiolarian ranges. This exercise shows major discrepancies between authors for the radiolarian ranges of the studied assemblage. Nevertheless, a Turonian age can be stated based on a synthesis of cited radiolarian ranges. This age is consistent with the age based on planktonic foraminifera. In combining the ages of both Radiolaria and planktonic Foraminifera, the studied samples can be restricted to the late Turonian. However, the discrepancies of published radiolarian ranges call for an urgent, major revision of the Late Cretaceous radiolarian biochronology. The integration of planktonic foraminifera with radiolarians may greatly enhance biochronologic resolution in sections where both groups occur.
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Mature T-cell and T/NK-cell neoplasms are both uncommon and heterogeneous, among the broad category of non-Hodgkin's lymphomas. Due to the lack of specific genetic alterations in the vast majority of cases, most currently defined entities show overlapping morphologic and immunophenotypic features and therefore pose a challenge to the diagnostic pathologist. The goal of the symposium is to address current criteria for the recognition of specific subtypes of T-cell lymphoma, and to highlight new data regarding emerging immunophenotypic or molecular markers. This activity has been designed to meet the needs of practicing pathologists, and residents and fellows enrolled in training programs in anatomic and clinical pathology. It should be a particular benefit to those with an interest in hematopathology. Upon completion of this activity, participants should be better able to: -To be able to state the basis for the classification of mature T-cell malignancies involving nodal and extranodal sites. -To recognize and accurately diagnose the various subtypes of nodal and extranodal peripheral T-cell lymphomas. -To utilize immunohistochemical and molecular tests to characterize atypical T-cell proliferations. -To recognize and accurately diagnose T-cell lymphoproliferative lesions involving the skin and gastrointestinal tract, and be able to provide guidance regarding their clinical aggressiveness and management -To be able to utilize flow cytometric data to identify diverse functional T-cell subsets.
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Este artículo presenta parte de los resultados de una investigación sobre la dinamización de las Tecnologías de la Información y la Comunicación (TIC) desde un centro de recursos pedagógico en las escuelas de su comarca, el Baix Ebre (Tarragona) durante los cursos escolares 2006-2007 y 2007-2008. Asimismo se enmarca en una tesis doctoral: «Disseny, implementació i avaluació del Pla d'explotació de recursos TIC als centres de primària del Baix Ebre» (Espuny, 2008). En líneas generales, se expone una propuesta sobre cómo dinamizar las TIC, basada en el análisis del papel de los agentes fundamentales en cualquier proceso de innovación, y con el objetivo de ser un referente en el diseño de un plan de incorporación de las TIC de forma gradual y metodológicamente significativa en la escuela. Se parte de un enfoque metodológico de investigación-acción y se utilizan técnicas de recogida e interpretación de datos mixta, cualitativa y cuantitativa (entrevistas, diarios, cuestionarios, demandas, opiniones, observaciones, reflexiones de expertos, etc.). A partir de ellas, nuestras conclusiones nos permiten reflexionar sobre el estado actual de las TIC en los centros y servir como base a las Administraciones educativas, en general, y a las diferentes comunidades educativas, en particular, en la definición de los cambios necesarios que nos permitan implementar exitosamente las TIC como un potente instrumento pedagógico que mejora la calidad del proceso de enseñanza-aprendizaje.
Resumo:
SEPServer is a three-year collaborative project funded by the seventh framework programme (FP7-SPACE) of the European Union. The objective of the project is to provide access to state-of-the-art observations and analysis tools for the scientific community on solar energetic particle (SEP) events and related electromagnetic (EM) emissions. The project will eventually lead to better understanding of the particle acceleration and transport processes at the Sun and in the inner heliosphere. These processes lead to SEP events that form one of the key elements of space weather. In this paper we present the first results from the systematic analysis work performed on the following datasets: SOHO/ERNE, SOHO/EPHIN, ACE/EPAM, Wind/WAVES and GOES X-rays. A catalogue of SEP events at 1 AU, with complete coverage over solar cycle 23, based on high-energy (~68-MeV) protons from SOHO/ERNE and electron recordings of the events by SOHO/EPHIN and ACE/EPAM are presented. A total of 115 energetic particle events have been identified and analysed using velocity dispersion analysis (VDA) for protons and time-shifting analysis (TSA) for electrons and protons in order to infer the SEP release times at the Sun. EM observations during the times of the SEP event onset have been gathered and compared to the release time estimates of particles. Data from those events that occurred during the European day-time, i.e., those that also have observations from ground-based observatories included in SEPServer, are listed and a preliminary analysis of their associations is presented. We find that VDA results for protons can be a useful tool for the analysis of proton release times, but if the derived proton path length is out of a range of 1 AU < s[3 AU, the result of the analysis may be compromised, as indicated by the anti-correlation of the derived path length and release time delay from the asso ciated X-ray flare. The average path length derived from VDA is about 1.9 times the nominal length of the spiral magnetic field line. This implies that the path length of first-arriving MeV to deka-MeV protons is affected by interplanetary scattering. TSA of near-relativistic electrons results in a release time that shows significant scatter with respect to the EM emissions but with a trend of being delayed more with increasing distance between the flare and the nominal footpoint of the Earth-connected field line.
Resumo:
Diplomityön tavoitteena oli selvittää erilaisia jatkojalostusmahdollisuuksia, joilla voidaan nostaa suuren mäntysahan tuotteiston arvoa. Lisäksi tuli tarkastella jalostuksen integrointia sahan tuotantoprosessiin. Työn taustalla on toisaalta puutuotemarkkinoiden muuttuminen ja toisaalta raaka-aineen laadullinen huononeminen. Molemmat seikat vaikuttavat negatiivisesti perinteisen mäntysahan kannattavuuteen .Jatkojalostuksen integroinnilla sahatavaraprosessiin saavutetaan säästöjä tuotantokustannuksissa, kun tarkastellaan koko prosessia tukista jatkojalosteeksi. Myös raaka-aineen tuottavuutta voidaan nostaa integraation avulla. Jatkojalostus voidaan integroida sahatavaraprosessiin raaka-aineen valikoinnilla sahatavaraprosessin eri osissa, on-line –jalostuksella sekä taloudellisesti. Sahatavaraprosessissa tapahtuva raaka-aineen valikointi voidaan suorittaa tukeista ja sahatavarasta. Valikointikriteerinä voi olla puun ominaisuudet, sahatavaran mitat ja laatu. Valikointiin voidaan nykyteknologiasta hyödyntää röntgentekniikkaa sekä konenäköä. On-line –jalostus tarkoittaa kiinteästi sahatavaraprosessiin liittyvää jalostusta, jolloin ns. turhia prosessivaiheita jää pois ja syntyy säästöjä. On-line –jalostuksen edellytys on raaka-aineen jonkin asteinen valikointi, esim. pituus. Taloudellisesti integroitu jalostus tarkoittaa, että jalostuslaitoksella pyritään nollatulokseen ja jalostuksen lisäarvo palautetaan sahan toimittamaan raaka-aineen hintaan. Tällainen toiminta yhtiön sisällä poistaa turhaa keskustelua raaka-aineen siirtohinnoista ja siten vapauttaa osaltaan resursseja tuottavampaan toimintaan. Erilaisten jatkojalostusmuotojen ja puun ominaisuuksien hyödyntämisen seulonnan perusteella löytyi yksi jalostusmuoto, jolla voidaan kohottaa mäntysahan tuotteiston arvoa. Työn tuloksena syntyi investointiehdotus aihiotankotuotannosta ikkunateollisuuden tarpeisiin. Raaka-aineen hyödynnettäviä ominaisuuksia ovat männyn sydänpuun luonnollinen kestävyys sekä keskimääräinen oksaväli. Valikointi tehdään välitukeista, joiden sahaamisen kannattavuus on männyn rungon osista heikoin. Aihiotankoprosessissa hyödynnetään konenäköä ja sormijatkostekniikkaa. Jatkojalostuksen integrointi sahatavaraprosessiin toteutetaan rakentamalla on-line –jalostuslaitos sekä soveltamalla röntgentekniikkaa raaka-aineen valinnassa.
Resumo:
Työn tavoitteena oli selvittää markkinalähtöiset mahdollisuudet erään puurakentamisen tuoteperheen kehittämiseksi pienpuusta valmistettavalla palkilla. Työssä käsiteltiin Suomen puupalkkimarkkinoita. Lisäksi työn tavoitteena oli tuoteperheen muiden kehittämismahdollisuuksien tutkiminen ja siinä käytettävän brändin käyttömahdollisuuksien pohtiminen. Ensiksi työssä tutustuttiin nykyiseen tuoteperheeseen. Tämän jälkeen kartoitettiin käytössä olevien puupalkkien ominaisuuksia ja kilpailukykyä. Sekä kirjallisten että puhelinhaastattelujen perusteella työssä perehdyttiin puupalkkien markkinoihin, markkinointiympäristön erityispiirteisiin ja etsittiin uudelle puupalkille kilpailukykyisiä ominaisuuksia. Brändien käyttömahdollisuuksia kartoitettiin perustuen lähinnä julkisiin kirjallisiin lähteisiin. Työssä tehdään esitys tuoteperheen täydentämiseksi pienpalkilla. Tulevaisuudessa sekä teollinen että yksityinen puurakentaminen ovat siirtymässä erilaisten rakentamisjärjestelmien käyttöön. Rakentamisen laatuvaatimukset ovat kiristymässä. Tämä johtaa rakentamisen tuotteiden ja tuotantomenetelmien kehittämiseen. Tuoteperheiden käyttö on lisääntymässä ja niiden merkitys kaupankäyntikokonaisuuden osana kasvaa myös puutuotteiden osalla.
Resumo:
Pro Gradu –työn aiheena on osaamisen kehittäminen henkilöstökoulutuksen avulla. Työn päätavoitteena on selvittää miten case-yrityksen, Etelä-Saimaan Sanomalehti Oy:n henkilöstölleen tarjoama koulutus saadaan kohdennettua parhaiten. Tutkimuksesta ilmenee, että koulutusten kohdentamisongelma case-yrityksessä johtuu sekä suunnitelmallisuuden puutteesta niiden toteuttamisessa että selkeiden tavoitteiden puuttumisesta. Case-yritykselle ehdotetaan henkilöstön kehittämisen liittämistä tiiviimmäksi osaksi yrityksen visiota ja strategioita. Työssä määritellään näiden pohjalta kullekin työtehtävälle osaamisen tavoitetaso. Yrityksessä aikaisemmin toteutetun koulutustarvekartoituksen sekä nyt suoritettujen esimieshaastattelujen perusteella saadaan selville osaamisen nykytaso. Nykyosaamista ja tavoitetasoa vertaamalla selvitetään yrityksen työntekijöiden yksilökohtainen koulutustarve, johon pyritään vastaamaan tarkoituksenmukaisella henkilöstökoulutuksella. Ennen empiiristä osuutta osaamisen kehittämisen taustoja kartoitetaan esittelemällä mitä osaaminen on ja kuinka sitä voidaan arvioida ja kehittää, keskittäen tarkastelu lopulta henkilöstökoulutukseen. Kirjallisen aineiston ja aikaisemman tutkimusmateriaalin lisäksi tutkimuksen toteuttamiseksi tarvittavia tietoja on hankittu esimieshaastatteluilla ja osallistuvalla havainnoinnilla.