Impact of SLM build parameters on the surface quality

Additive manufacturing by melting of metal powders is an innovative method to create one-offs and customized parts. Branches like dentistry, aerospace engineering and tool making were indicated and the manufacturing methods are established. Besides all the advantages, like freedom of design, manufacturing without a tool and the reduction of time-to-market, there are however some disadvantages, such as reproducibility or the surface quality. The surface quality strongly depends on the orientation of the component in the building chamber, the process parameters which are laser power and exposure time, but also on the so-called “hatch”-strategy, which includes the way the laser exposes the solid areas. This paper deals with the investigation and characterization of the surface quality of generated parts produced by SLM. Main process parameters including part orientation, part size and hatch strategies are investigated and monitored. The outcome is a recommendation of suitable hatch strategies depending on desired part properties. This includes metered values and takes into account process stability and reproducibility.

Encore® Implant Use in Feedlot Steers

A feedlot demonstration utilizing Encore®, a new longterm implant product, was completed at the Allee Demonstration Farm at Newell, Iowa in 1999. Seventyone steers (697 lbs.) were allotted by weight and hide color and assigned to one of three treatments: 1) Encore® (43.9 mg estradiol = E) on day 0; 2) Encore® plus Component® TS (140 mg trenbolone acetate = ETS0) on day 0; or 3) Encore® on day 0 followed by Component® TS (ETS100) on day 100. Due to wide standard deviation in the weight of steers at the beginning of the demonstration, cattle were harvested in two groups. Approximately half of each treatment group was sorted by visual appraisal as to market readiness. Statistical interactions existed within treatment group between first and second harvest dates, therefore data were split and analyzed accordingly. In the first harvest group, ETS0 steers had higher marbling scores than ETS100 steers, and lower average daily gain than E steers and ETS100 steers. In the second harvest group, ETS0 steers had more fat at the 12th/13 rib than ETS100 steers, but did not differ from E steers. Marbling scores were also higher for ETS0 steers than either ETS100 or E steers in the second harvest group. Pooled data reveal that ETS0 steers had higher marbling scores than ETS100 steers and tended to have higher marbling scores than E steers. First harvest E and ETS100 steers had greater average daily gain than ETS0 steers. In the second harvest group, ETS0 steers had heavier final ending weights than E steers but did not differ from ETS100 steers. Final ending weights, rib eye area, fat thickness at the 12th/13th rib, KPH fat, and calculated yield grades did not differ among treatment groups in the pooled data.

Alternative Cow Herd Investment Strategies: Constant Size and Constant Investment

Two heifer replacement strategies were compared over a 25-year period. One strategy retained the same number of heifers each year to maintain a constant herd size. The second strategy retained the same dollar value of heifer calves each year based on their opportunity cost as feeder calves. The constant investment strategy herd size varied throughout the period, but generated higher average profit and higher net worth than did the constant herd size strategy. Constant investment is a simple strategy to adjust the level of investment in beef cows and the resource base (pasture, labor, winter feed) in response to market signals driven by the cattle cycle. This strategy automatically increases heifer retention when the opportunity cost is low and reduces the number retained when cost is high. The effect is a lower average cost of cows in the herd, lower overall investment, and a higher net return on investment. Iowa producers, who often have greater flexibility in land use than producers in other major beef cow regions, can better utilize this strategy that generates greater profits and net worth growth.

NANOPARTICLE AGGLOMERATES FOR PULMONARY DRUG DELIVERY

The Pulmonary route has been traditionally used to treat diseases of the respiratory tract. However, important research within the last two decades have shown that in addition to treating local diseases, a wide range of systemic diseases can be treated by delivering drugs to the lungs. The recent FDA approval to market Exubera, an inhalable form of insulin developed by Pfizer, to treat Diabetes, may just be the stepping stone that the pharmaceutical industry needs to market other drugs to treat systemic diseases via the lungs. However, this technology still needs repeated drug doses to control glucose levels, as the inhaled drug is cleared rapidly. Technologies have been developed where inhaled particles are capable of controlled release of drug from the lungs. An important feature of these technologies is the large geometric size of the particles that makes it difficult for the lung macrophages to clear these particles, which results in longer residence times for the particles in the lungs. Owing to the porosity, these particles have lower densities making them deliverable to the deep lungs. However, no modulation of drug release can be achieved with these technologies when more drug release may be required. This additional requirement can only be assuaged by additional dosing of the drug formulation, which can have undesirable effects due to excess loading of excipients in the lungs. In an attempt to bring about modulation of release from long residence time particles, a novel concept was developed in our laboratory that has been termed as the Agglomerated Vesicle Technology (AVT). Liposomes with encapsulated drug were agglomerated using well known cross linking chemistries to form agglomerates in the micron sized range. The large particles exhibited aerodynamic sizes in the respirable size range with minimal damage to the particles upon nebulization. By breaking the cross links between the liposomes with a cleaving agent, it was anticipated that triggered release of drug from the AVT particles could be achieved. In vivo studies done in healthy rabbits showed that post-administration modulation of drug release is possible from the AVT particles after the introduction of the cleaving agent. This study has important implications for the future development of this technology, where the AVT particles can be made “sensitive” to the product of disease. It is envisaged that a single dose of AVT containing the appropriate drug when administered to the lungs would maintain drug levels at a controlled rate over an extended period of time. When the need for more drug arises, the product of the disease would trigger the AVT particles to release more drug as needed to control the condition, thus eliminating the need for repeated drug doses and improved compliance amongst patients.

Intellectual Property and Traditional Cultural Expressions in a Digital Environment. Preface

In the face of increasing globalisation, there is a pressing need for innovative trans-disciplinary analyses of the value of traditional cultural expressions (TCE) that also suggest appropriate protection mechanisms for them. The book to which this preface belongs combines approaches from history, philosophy, anthropology, sociology and law, and charts previously untravelled paths for developing new policy tools and legal designs that go beyond conventional copyright models. It reflects also upon the specific features of the digital environment, which, despite enhancing the risks of misappropriation of traditional knowledge and creativity, may equally offer some opportunities for revitalising indigenous peoples' values and provide for the sustainability of TCE.

The role of commercial actors in snowboarding

Commercial actors play an essential role in the organisational structure of snowboarding by sponsoring athletes, arranging events, contributing to product development and developing long-term partnerships with other key actors. However, the particularities of their role in the alternative sports cultures which are related to brand marketing strategies have not been extensively researched. Based on Hitzler and Niederbachers (2010) framework of social scenes, Stegbauers (2008) social network and Adjouri and Stastnys (2006) branding theories, analysis is carried out using an ethnographic approach. This includes participant observation of relevant events and semi-structured interviews with over forty key actors of the sport to examine the roles and activities of core actors within snowboarding. The findings reveal that brands have gained an important position within the scene; where they can build partnerships with other core and periphery actors in order to market particularly identities, lifestyles and products. This contributes to the development of a sport which is dependent on brands for its continuity. By using promotional strategies of sponsoring athletes, organising events and feeding media with scene-related content, the aesthetical values of the snowboarding sport are communicated and transferred, while ensuring exposure of the brand’s image and lifestyle. Social contacts as well as knowledge on particularities of the sport allow the commercial actors to gain an influential position and identity within the snowboarding core culture. Keywords: commercial actors, alternative sport cultures, social networks, brands, snowboarding References Adjouri, N. & Stastny, P. (2006). Sport-Branding: Mit Sport-Sponsoring zum Markenerfolg. Wiesbaden: Gabler. Hitzler, R. & Niederbacher, A. (2010). Leben in Szenen: Formen juveniler Vergemeinschaftung heute. Wiesbaden: VS Verlag für Sozialwissenschaften. Stegbauer, C. (2008). Netzwerkanalyse und Netzwerktheorie. Ein neues Paradigma in den Sozialwissenschaften. Wiesbaden: VS Verlag für Sozialwissenschaften.

Three essays on prices and selection

Competitive Market Segmentation Abstract In a two-firm model where each firm sells a high-quality and a low-quality version of a product, customers differ with respect to their brand preferences and their attitudes towards quality. We show that the standard result of quality-independent markups crucially depends on the assumption that the customers' valuation of quality is identical across firms. Once we relax this assumption, competition across qualities leads to second-degree price discrimination. We find that markups on low-quality products are higher if consuming a low-quality product involves a firm-specific disutility. Likewise, markups on high-quality products are higher if consuming a high-quality product creates a firm-specific surplus. Selection upon Wage Posting Abstract We discuss a model of a job market where firms announce salaries. Thereupon, they decide through the evaluation of a productivity test whether to hire applicants. Candidates for a job are locked in once they have applied at a given employer. Hence, such a market exhibits a specific form of the bargain-then-ripoff principle. With a single firm, the outcome is efficient. Under competition, what might be called "positive selection" leads to market failure. Thus our model provides a rationale for very small employment probabilities in some sectors. Exclusivity Clauses: Enhancing Competition, Raising Prices Abstract In a setting where retailers and suppliers compete for each other by offering binding contracts, exclusivity clauses serve as a competitive device. As a result of these clauses, firms addressed by contracts only accept the most favorable deal. Thus the contract-issuing parties have to squeeze their final customers and transfer the surplus within the vertical supply chain. We elaborate to what extent the resulting allocation depends on the sequence of play and discuss the implications of a ban on exclusivity clauses.

Elaboración de vinos : defectos en el proceso que originan costos de no calidad

Los costos de calidad se asocian a su planificación, control, evaluación de la conformidad y a los costos ocasionados por no cumplir con los requisitos de satisfacción de la fábrica o del cliente (productos o servicios con defectos). Los objetivos del trabajo son identificar las causas que provocan la ausencia o pérdida de calidad (no calidad), proponer acciones correctivas en el proceso de elaboración de vinos, midiendo la frecuencia de aparición y clasificando los costos de no calidad. Conocer la frecuencia de aparición de las causas de no calidad en las etapas del proceso de elaboración de vinos permitirá optimizar la gestión y reducir los costos al disminuir sus correcciones. El estudio identifica los factores que alteran la calidad de los vinos. La mayor frecuencia de defectos es de origen prefermentativo, que junto con los de crianza, conservación y originados en el viñedo explican el 79% de los mismos. Los defectos encontrados constituyen costos de prevención y evaluación pero serán falla interna si la bodega está integrada y se atribuirán a falla externa en el caso de productor no integrado. Los establecimientos en los que se pudo identificar y establecer frecuencia de aparición de los defectos que influyen en la calidad del vino son aquellos que tienen algún sistema de gestión de la calidad, ya que han normalizado los registros que actuarán como herramienta de gestión. Los encargados de gerenciar las bodegas deberían conocer los puntos críticos del proceso para realizar la gestión preventiva de los posibles defectos. Los costos que inciden en la calidad del producto a comercializar se deben registrar y controlar, y trazarlos hacia adelante para conocer la incidencia de los mismos en los precios finales, y hacia atrás para que en la planificación de la próxima elaboración se contemple la prevención correspondiente.

El comercio indio-criollo en La Guajira colombo-venezolana : Intercambios, disputas y reglamentaciones 1840-1861

Más allá de la imagen construida por una "historiografía" de corte "romántico" y "liberal" sobre los indígenas durante el siglo XIX, en el sentido de que éstos fueron una traba al desarrollo económico y social, este artículo demuestra que los nativos de La Guajira colombo-venezolana en el período 1840-1861, se insertaron en el mundo de la circulación de bienes agropecuarios, llevando al mercado de las poblaciones venezolanas de Sinamaica y Las Guardias de Afuera sus excedentes productivos, accediendo a cambio a distintos géneros de los que carecían. A pesar de que el intercambio también generó disputas entre indios y criollos, también se reconoció por las autoridades el beneficio del comercio para la provincia de Maracaibo, razón por la cual éste fue reglamentado

El comercio indio-criollo en La Guajira colombo-venezolana : Intercambios, disputas y reglamentaciones 1840-1861

Más allá de la imagen construida por una "historiografía" de corte "romántico" y "liberal" sobre los indígenas durante el siglo XIX, en el sentido de que éstos fueron una traba al desarrollo económico y social, este artículo demuestra que los nativos de La Guajira colombo-venezolana en el período 1840-1861, se insertaron en el mundo de la circulación de bienes agropecuarios, llevando al mercado de las poblaciones venezolanas de Sinamaica y Las Guardias de Afuera sus excedentes productivos, accediendo a cambio a distintos géneros de los que carecían. A pesar de que el intercambio también generó disputas entre indios y criollos, también se reconoció por las autoridades el beneficio del comercio para la provincia de Maracaibo, razón por la cual éste fue reglamentado

El comercio indio-criollo en La Guajira colombo-venezolana : Intercambios, disputas y reglamentaciones 1840-1861

Más allá de la imagen construida por una "historiografía" de corte "romántico" y "liberal" sobre los indígenas durante el siglo XIX, en el sentido de que éstos fueron una traba al desarrollo económico y social, este artículo demuestra que los nativos de La Guajira colombo-venezolana en el período 1840-1861, se insertaron en el mundo de la circulación de bienes agropecuarios, llevando al mercado de las poblaciones venezolanas de Sinamaica y Las Guardias de Afuera sus excedentes productivos, accediendo a cambio a distintos géneros de los que carecían. A pesar de que el intercambio también generó disputas entre indios y criollos, también se reconoció por las autoridades el beneficio del comercio para la provincia de Maracaibo, razón por la cual éste fue reglamentado

Tertiary flora of Saxony

The thesis represents the first part of a reference book to the Tertiary flora of Saxony. All taxa based on leaves of angiosperms and on Ginkgo are included in this compendium. After an overview about the geological state of knowledge on the Tertiary in Saxony, phytostratigraphic concepts are introduced and a historical survey on the Tertiary paleobotanical research in Saxony is given. All plant macrofossils published from Saxonian Tertiary until end of 2013 and their sites of discovery (primary data) were recorded. This data were supplemented by additional attributes and unified through project-based M.Sc. theses. Subsequently, taxa of fossil leaves were selected, their data evaluated and brought to a consistent state of research. Data sheets for 187 out of 235 examined taxa were established for a determination atlas. Macro- and micromorphological attributes are described in this atlas and information are given about the systematic, synonymy, palaeoecology and spatial and temporal distribution. The describing part is illustrated by images and instructive drawings. The documented data were surveyed and discussed related to their quality within the literature in the result part. A bibliography of the extensive palaeobotanical literature for plant fossils of Saxony completes the work. The taxon and locality related data are implemented into an open source geographical information system (GIS) in order to visualize and to manage them effectively. For the first time, the results of this thesis implemented in the GIS allow the generation of distribution maps for the taxa of leaves of Tertiary angiospermes and Ginkgo in Saxony. Furthermore it enables to query topographical, geological and paleobotanical information about the fossil sites. A determination key was developed for the fossil material that allows a rough determination of the findings in the field. The compendium will be available for free use in a printed as well as in a digital version.

Subsidies, Clean Energy, and Climate Change

Estimates show that fossil fuel subsidies average USD 400–600 billion annually worldwide while renewable energy (RE) subsidies amounted to USD 66 billion in 2010 and are predicted to rise to USD 250 billion annually by 2035. Domestic political rationales for energy subsidies include promoting innovation, job creation and economic growth, energy security, and independence. Energy subsidies may also serve social and environmental goals. Whether and to what extent subsidies are effective to achieve these goals or instead lead to market distortions is a matter of much debate and the trade effects of energy subsidies are complex. This paper offers an overview of the types of energy subsidies that are used in the conventional and renewable energy sectors, and their relationship with climate change, in particular greenhouse gas emissions. While the WTO’s Agreement on Subsidies and Countervailing Measures (ASCM) is mostly concerned with harm to competitors, this paper considers the extent to which the Agreement could also discipline subsidies that cause harm to the environment as a global common. Beyond the existing legal framework, this paper surveys a number of alternatives for improving the ability of subsidies disciplines to internalize climate change costs of energy production and consumption. One option is a new multilateral agreement on subsidies or trade remedies (with an appropriate carve-out in the WTO regime to allow for it if such an agreement is concluded outside it). Alternatively, climate change-related subsidies could be included as part of another multilateral regime or as part of regional agreements. A third approach would be to incorporate rules on energy subsidies in sectorial agreements, including a Sustainable Energy Trade Agreement such as has been proposed in other ICTSD studies.

Stunted and Distorted Industrialization in Myanmar

More than 15 years have passed since Myanmar embarked on its transition from a centrally planned economy to a market-oriented one. The purpose of this paper is to provide a bird-eye's view of industrial changes from the 1990s up to 2005. The industrial sector showed a preliminary development in the first half of the 1990s due to an "open door" policy and liberalization measures. However, a brief period of growth failed to effect any changes in the economic fundamentals. The industrial sector still suffers from poor power supplies, limited access to imported raw materials and machinery, exchange rate instability, limited credit, and frequent changes of government regulation. Public ownership is still high in key infrastructure sectors, and has failed to provide sufficient services to private industries. What the government must do first is to get the fundamentals right.