Improving Transition Outcomes: Henry County Transition Partners: Directory Part 2

Part 2 of 3 for Henry County's Transition Partners Resource Directory specific to youth with disabilities transitioning from high school to employment, post-secondary education, or adult services.

Improving Transition Outcomes: Henry County Transition Partners: Directory Part 3

Part 3 of 3 for Henry County's Transition Partners Resource Directory specific to youth with disabilities transitioning from high school to employment, post-secondary education, or adult services.

Improving Transition Outcomes: Henry County Transition Partners Prototype: General Information

General information on the Henry County Transition Partners community prototype under Improving Transition Outcomes with Iowa Vocational Rehabilitation Services.

Improving Transition Outcomes: Henry County Transition Partners: Youth Interview Invitation

Henry County's Transition Partners' youth focus group interview invitation.

Improving Transition Outcomes: Henry County Transition Partners: Teacher Interview Invitation

Henry County's Transition Partners' focus group invitation specifically for teachers.

Improving Transition Outcomes: Henry County Transition Partners Prototype: Interview Questions

Interview questions used by Henry County Transition Partners during focus groups and individual interviews.

Audit report on the City of Van Horne, Iowa for the year ended June 30, 2007

Audit report on the City of Van Horne, Iowa for the year ended June 30, 2007

Audit report on the City of Van Meter, Iowa for the year ended June 30, 2008

Audit report on the City of Van Meter, Iowa for the year ended June 30, 2008

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation.

Infectious and inflammatory diseases have repeatedly shown strong genetic associations within the major histocompatibility complex (MHC); however, the basis for these associations remains elusive. To define host genetic effects on the outcome of a chronic viral infection, we performed genome-wide association analysis in a multiethnic cohort of HIV-1 controllers and progressors, and we analyzed the effects of individual amino acids within the classical human leukocyte antigen (HLA) proteins. We identified >300 genome-wide significant single-nucleotide polymorphisms (SNPs) within the MHC and none elsewhere. Specific amino acids in the HLA-B peptide binding groove, as well as an independent HLA-C effect, explain the SNP associations and reconcile both protective and risk HLA alleles. These results implicate the nature of the HLA-viral peptide interaction as the major factor modulating durable control of HIV infection.