Modelagem computacional das túnicas cardíacas para processamento e controle de qualidade

This paper considers a study of the anatomical features of the cardiac system and a three-dimensional model of the different tunics that comprise the heart wall, for processing and quality control of radiological images. The structures are built by the layer overlapping method, where a layer can be understood as a slice of the three-dimensional object. The pericardium, myocardium and endocardium were represented with three-dimensional cylinders and hexagons. The spatial arrangement of the cardiac system is determined by an background image of a real model, which values are defined according to the shape of the region and on the anatomical patients characteristics. The results are significant, considering the anatomical structures details, as well as the representation of the thicknesses of the regions of the heart wall. The validation of the anatomical model was accomplished through comparisons with dimensions obtained from a real model and allows verifying that the model is appropriate. The degree of representation will allow the verification of the influence of radiological parameters, morphometric peculiarities and stage of the diseases on the quality of the images, as well as on the performance of the Computer-Aided Diagnosis (CAD).

Parâmetros Neuropáticos no Diabetes Mellitus

Pós-graduação em Fisioterapia - FCT

Antidepressivo modula o comportamento e a expressão gênica das cadeias de miosina, serca2 e fosfolambam em ratos com insuficiência aórtica?

Introduction: Aortic insufficiency (AoI), a volume overload, is characterized by the diastolic reflux of blood from the regurgitating aorta to the left ventricle. This effect results from malfunctioning aortic cusps. The main cause of AoI in developing countries is rheumatic fever, including Brazil, and valvar degeneration in developed countries. There is a strong association between cardiovascular diseases and depression. Selective serotonin reuptake inhibitors (SSRI) are one of the most prescribed antidepressants in the world. Previous studies of our laboratory showed that the utilization of a SSRI, paroxetine, improved cardiac function in rats with sub-chronic AoI and reduced the daily ingestion of hypertonic sodium (NaCl 0,3M). Cardiovascular diseases can determine behavior changes like increase of anxiety, and it is yet unknown if AoI would determine anxiety or anhedonia, incapacity of obtaining pleasure through physical or sensorial experiences. A possible target for SSRI action could be a change in the expression of enzyme isoforms that collaborate in the contractile function of the heart muscle, like the heavy chains of myosine, the sarcoplasmatic reticulum Ca2+/ATPase (SERCA) and its regulator protein, phospholamban (PLB). Objectives: Evaluation of behavior parameters for anxiety and anhedonia state and genic expression of a-myosine, b-myosine, SERCA2a and PLB in the heart tissue of rats with subchronic AoI that received treatment with an SSRI (paroxetine) for 4 weeks. Methods: Surgery to induce AoI was performed on male Wistar rats, anxiety was evaluated by the elevated plus-maze (EPM) and state of anhedonia was tested by ingestion of 2% sucrose solution. After euthanasia the heart tissue was collected and total RNA was extracted to be analyzed by the RT-qPCR method. Results: Heart fractional shortening was preserved in rats with AoI that were treated compared to rats with AoI that were not treated. There was no statistically ...

Associação entre o potencial evocado auditivo de longa latência e os índices lineares da variabilidade da frequência cardíaca em repouso

Pós-graduação em Fonoaudiologia - FFC

Variabilidade da frequência cardíaca, funções cognitivas e nível de atividade física em pacientes com doença de Alzheimer

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Parâmetros ecocardiográficos e variabilidade da frequência cardíaca em fêmeas caninas com sepse de ocorrência natural devido à piometra e suas correlações com valores séricos de TNF-alfa, IL-1 beta, IL-6, IL-10 e proteína C reativa

Pós-graduação em Medicina Veterinária - FCAV

Efeito dos hábitos comportamentais e gordura corporal sobre indicadores de risco cardiovasculares entre adolescentes: estudo de coorte de 12 meses

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Expressão das proteínas envolvidas no trânsito de cálcio miocárdico de ratos obesos por dieta hiperlipídica saturada

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Respostas da frequência cardíaca ao teste de 1RM e da modulação autonômica da frequência cardíaca no período de recuperação em indivíduos com fatores de risco para doenças cardiovasculares

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Comparação entre a variação da pressão de pulso e o índice de variabilidade pletismográfica como índices dinâmicos de pré-carga em cães anestesiados com isoflurano submetidos à hemorragia hipotensiva por reposição volêmica

Pós-graduação em Anestesiologia - FMB

Modulação autonômica cardíaca após exercícios com haste oscilatória em ambos os sexos

Pós-graduação em Fisioterapia - FCT

Distance exercised during submaximal training on race winnings for Thoroughbred racehorses

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influência da obesidade induzida por dieta hiperlipídica saturada sobre o comportamento da via beta-adrenérgica miocárdica em ratos Wistar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Presença de fatores de risco dependentes ou não de esforço físico em praticantes de corrida de rua

In order to reduce the sedentarism and to improve population's health condition, many physical activity incentive programs have been stimulated. As a result, many people have adhered to street racing, but their health condition is almost always ignored. The aim of this study was to evaluate street racers' health condition, identifying the presence of cardiovascular risk factors as well as problems associated to street racing. The study case was composed by 111 racers from the town of Bauru (94 men and 17 women) aged in average 39±13 years old, who were evaluated in 4 street race competitions. The subjects answered to an anamnesis with questions about their socioeconomic status, medicine use, cardiovascular risk, physical exercise practices, and issues related to racing and injury. Weight (kg) and height (m) were measured to calculate the body mass index (BMI, kg/m²) as well as systolic and diastolic blood pressure (BP), heart rate (HR), abdominal circumference (AC), and flexibility. It could be observed that the majority of racers were Caucasian, married and belonged to social classes over C. The prevalent age was between 18 and 35 years old (42%). Among the participants, 38.7% have already undergone some kind of surgery and 13% declared having some health problem. The questionnaire pointed out that 36% had low and moderate cardiovascular risk. It could be noticed from the AC that 10% of men and 18% of women had high cardiac risk. Among the tested, 43.2% (24.3% altered and 18.9% borderline) showed high BP on the day of the test, but only 2.7% had self-declared hypertensive. In relation to injury, 36% had already had lesions of some kind, 27.5% of which had occurred in the last 8 months. 66.6% had derived from training or racing competitions and the knee was the mostly affected body part. Only 43% had professional orientation by a physical education teacher during their training and the main reasons for them to begin racing practice were...

Variação aguda da frequência cardíaca durante série de hipertrofia para grupo flexor e extensor do cotovelo

Currently individuals are affected by a routine busy and they don't have time for physical activity, highlighting the sedentary lifestyle, a risk factor for cardiovascular diseases. For this reason, it focuses too much on cardiovascular diseases and the importance of physical practice. With the largest divulgation and variety of physical activities, activities that were not as practiced became popular, as is the case of resistive exercise. Much is said of the influence of resistance exercise in physical strength, in muscle development and in the quest for a more defined body. However, studies have shown beneficial contributions of resistance exercise on the cardiovascular system. During the physical effort, some changes occur in the body in order to meet the increased demand for oxygen. Among them is the increase in heart rate (HR), which varies with the intensity of effort. Thus, this research sought to contribute with an analysis of the HR behavior before, during and after 3 sets of hypertrophy, as far for the flexor group of the elbow as to the extensor group. It was observed that, although the HR has increased in the course of the series, the variations of HR were not significant between the flexor group and extensor group of the elbow joint. Also were not significant the differences between the variations of the HR from the 1ª to the 2ª series between the flexor group and extensor group, as well as to the variations from the 2ª to the 3ª series