1000 resultados para Surin, Jean-Joseph (1600-1665)


Relevância:

30.00% 30.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Mode of access: Internet.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Added t.-p., with title: Les abus dans les ceremonies et dans les mœurs developpé par Monsieur xxx. Earlier editions appeared under this title.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

"Bibliographie": p. [229]-236.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

"Commentaire ... fait en société avec Blin de Sainmore."--Brunet, Manuel du libraire. 5. éd.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

Reprinted from a larger work.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

After the death of baron James de Rothschild the publication of the remaining volumes was undertaken by Emile Picot.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

A jelentés nem jöhetett volna soha jobbkor. A felkérés még 2008 februárjában történik. Akkor, amikor sok szakértő azt nyilatkozza, hogy a válságot Európa meg fogja úszni. Valószínűleg a megbízó, Nicolas Sárközy francia elnök sem előrelátóbb, de ösztönösen ráérez a problémára és a lehetőségre. Vagy okos tanácsadói javasolják. A válság mindenesetre még egyértelműbbé teszi, hogy statisztikai rendszerünk több szempontból is tökéletlen. A bizottság mandátuma eredetileg szerényebb, de az új események fényében tevékenységük felértékelődik. A rangos munkaközösség tagjai Joseph E. Stiglitz (Columbia Egyetem) és Amartya Sen (Harvard Egyetem) Nobel-díjasok, a testület koordinátorának Jean-Paul Fitoussi neves francia professzort kérik fel. Rajtuk kívül még 21 közismert szakértő vesz részt a munkában, főként amerikai és francia egyetemekről. A jelentést 2009. szeptember 14-én mutatják be egész napos konferencia keretében a Sorbonne egyetem aulájában.

Relevância:

30.00% 30.00%

Publicador:

Resumo:

The exponential growth of studies on the biological response to ocean acidification over the last few decades has generated a large amount of data. To facilitate data comparison, a data compilation hosted at the data publisher PANGAEA was initiated in 2008 and is updated on a regular basis (doi:10.1594/PANGAEA.149999). By January 2015, a total of 581 data sets (over 4 000 000 data points) from 539 papers had been archived. Here we present the developments of this data compilation five years since its first description by Nisumaa et al. (2010). Most of study sites from which data archived are still in the Northern Hemisphere and the number of archived data from studies from the Southern Hemisphere and polar oceans are still relatively low. Data from 60 studies that investigated the response of a mix of organisms or natural communities were all added after 2010, indicating a welcomed shift from the study of individual organisms to communities and ecosystems. The initial imbalance of considerably more data archived on calcification and primary production than on other processes has improved. There is also a clear tendency towards more data archived from multifactorial studies after 2010. For easier and more effective access to ocean acidification data, the ocean acidification community is strongly encouraged to contribute to the data archiving effort, and help develop standard vocabularies describing the variables and define best practices for archiving ocean acidification data.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Machado-Joseph disease (MJD/SCA3) is the most frequent spinocerebellar ataxia, characterized by brainstem, basal ganglia and cerebellar damage. Few magnetic resonance imaging based studies have investigated damage in the cerebral cortex. The objective was to determine whether patients with MJD/SCA3 have cerebral cortex atrophy, to identify regions more susceptible to damage and to look for the clinical and neuropsychological correlates of such lesions. Forty-nine patients with MJD/SCA3 (mean age 47.7 ± 13.0 years, 27 men) and 49 matched healthy controls were enrolled. All subjects underwent magnetic resonance imaging scans in a 3 T device, and three-dimensional T1 images were used for volumetric analyses. Measurement of cortical thickness and volume was performed using the FreeSurfer software. Groups were compared using ancova with age, gender and estimated intracranial volume as covariates, and a general linear model was used to assess correlations between atrophy and clinical variables. Mean CAG expansion, Scale for Assessment and Rating of Ataxia (SARA) score and age at onset were 72.1 ± 4.2, 14.7 ± 7.3 and 37.5 ± 12.5 years, respectively. The main findings were (i) bilateral paracentral cortex atrophy, as well as the caudal middle frontal gyrus, superior and transverse temporal gyri, and lateral occipital cortex in the left hemisphere and supramarginal gyrus in the right hemisphere; (ii) volumetric reduction of basal ganglia and hippocampi; (iii) a significant correlation between SARA and brainstem and precentral gyrus atrophy. Furthermore, some of the affected cortical regions showed significant correlations with neuropsychological data. Patients with MJD/SCA3 have widespread cortical and subcortical atrophy. These structural findings correlate with clinical manifestations of the disease, which support the concept that cognitive/motor impairment and cerebral damage are related in disease.

Relevância:

20.00% 20.00%

Publicador:

Resumo:

Machado-Joseph disease (SCA3) is the most frequent spinocerebellar ataxia worldwide and characterized by remarkable phenotypic heterogeneity. MRI-based studies in SCA3 focused in the cerebellum and connections, but little is known about cord damage in the disease and its clinical relevance. To evaluate the spinal cord damage in SCA3 through quantitative analysis of MRI scans. A group of 48 patients with SCA3 and 48 age and gender-matched healthy controls underwent MRI on a 3T scanner. We used T1-weighted 3D images to estimate the cervical spinal cord area (CA) and eccentricity (CE) at three C2/C3 levels based on a semi-automatic image segmentation protocol. The scale for assessment and rating of ataxia (SARA) was employed to quantify disease severity. The two groups-SCA3 and controls-were significantly different regarding CA (49.5 ± 7.3 vs 67.2 ± 6.3 mm(2), p < 0.001) and CE values (0.79 ± 0.06 vs 0.75 ± 0.05, p = 0.005). In addition, CA presented a significant correlation with SARA scores in the patient group (p = 0.010). CE was not associated with SARA scores (p = 0.857). In the multiple variable regression, we found that disease duration was the only variable associated with CA (coefficient = -0.629, p = 0.025). SCA3 is characterized by cervical cord atrophy and antero-posterior flattening. In addition, the spinal cord areas did correlate with disease severity. This suggests that quantitative analyses of the spinal cord MRI might be a useful biomarker in SCA3.