987 resultados para State Bar of Michigan
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Audit report of Iowa State University of Science and Technology, Ames, Iowa, and its discretely presented component unit as of and for the years ended June 30, 2013 and 2012
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Audit report of the State University of Iowa, Iowa City, Iowa, (University of Iowa) and its discretely presented component units as of and for the years ended June 30, 2013 and 2012
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Report on the State University of Iowa, Iowa City, Iowa for the year ended June 30, 2013
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Report on Iowa State University of Science and Technology, Ames, Iowa, for the year ended June 30, 2013
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Report on a review of selected general and application controls over the Iowa State University of Science and Technology student financial aid system for the period of April 22, 2013 through May 17, 2013
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Audit report of Debt Service and Coverage for Iowa State University of Science and Technology as of June 30, 2014
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AB Summary: Steady state concentrations of (S)- and (R)-mianserin and desmethylmianserin were measured in 21 homozygous extensive metabolizers (as determined by genotyping for mutations 3 [or A] and 4 [or B]), in seven heterozygous extensive metabolizers and in one poor metabolizer of debrisoquine, as well as in one patient receiving very high doses of mianserin (360 mg/day) and fluoxetine (160 mg/day), a strong cytochrome P450IID6 inhibitor. The mean dose of mianserin was (mean +/- SD, range: 67 +/- 63, 10 to 360 mg/day). High dispersions of the (S)/(R)-mianserin and desmethylmianserin ratios were observed (mean +/- SD, range: 2.10+/- 1.01, 0.64 to 4.76, and 0.29 +/- 0.14, 0.08 to 0.57, respectively). The highest (S)/(R)-mianserin ratio was calculated for the poor metabolizer (4.76) agreeing with those results of a single-dose study with poor and extensive metabolizers of debrisoquine, in that the cytochrome P450IID6 is probably involved in the metabolism of mianserin with an enantioselectivity for the (S)-enantiomer. Nevertheless, the mean concentration-to-dose ratios for (S)- or (R)-mianserin or desmethylmianserin were not significantly different between homozygous and heterozygous extensive metabolizers, and no particular values were measured in the poor metabolizer nor in the patient receiving fluoxetine. Furthermore, the(S)/(R)-mianserin ratio measured in the PM was only slightly higher than the second highest ratio (3.85) of an homozygous extensive metabolizer, whereas no particular value (2.92) was calculated for the patient taking fluoxetine. Finally, no significant differences in (S)/(R)-mianserin or(S)/(R)-desmethylmianserin were calculated between homozygous and heterozygous extensive metabolizers. Although the number of patients included in this study is too low to allow definite conclusions, the results suggest that the debrisoquine genotype has only a moderate influence on the steady state concentrations of the enantiomers of mianserin and desmethylmianserin. (C) Lippincott-Raven Publishers
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Report on the State University of Iowa, Iowa City, Iowa for the year ended June 30, 2014
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Report on Iowa State University of Science and Technology, Ames, Iowa for the year ended June 30, 2014
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Report on a review of selected general and application controls over the State University of Iowa MAUI Student Financial Aid system for the period May 19, 2014 through July 31, 2014
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Report on a review of selected general and application controls over the Iowa State University of Science and Technology Kuali Financial System for the period April 30, 2014 through May 28, 2014
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This five-year plan,1993-1997,describes the needs, goals, objectives, and methodology for each of the Library Services and Construction Act goals. The LSCA long range plan is revised and issued on an annual basis.
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Audit report of the State University of Iowa, Iowa City, Iowa, (University of Iowa) for the years ended June 30, 2015 and 2014
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Audit report of Iowa State University of Science and Technology, Ames, Iowa, (Iowa State University) as of and for the years ended June 30, 2015 and 2014