992 resultados para Sinn Féin


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hrsg. von A. E. Kaplan ...

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Boberach: Die französische Revolution hat gezeigt, daß die Beseitigung der Vorrechte des Adels und des Gottesgnadentums der Könige nur unheilvolle Folgen hat

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Welsch (Projektbearbeiter): Propagierung einer Methode zur Überwindung der herrschenden Arbeitslosigkeit und Finanznot (in der Form einer Unterhaltung zwischen einem Bürger und einem Arbeiter): Arbeiter und Bürger sind aufeinander angewiesen und sollten sich nicht gegeneinander kehren. Vonnöten ist zuallererst Vertrauen zwischen Bürgern und Arbeitern und sodann die Abtragung der Schulden. Die Verschuldung der Regierung in Staatspapieren ist von Übel, denn sie verhindert, daß brachliegendes Kapital wieder in den Wirtschaftskreislauf gelangt; die Folge ist Arbeitslosigkeit. Der Ausweg liegt in der Abkehr von der Schuldenwirtschaft (Entwertung der Staatspapiere) sowie in privaten Spenden seitens des Königs und der vermögenden Teile der Bevölkerung "Gold und Silber [a]uf den Altar des Vaterlands". So wird dreierlei bewirkt: Wiederherstellung des Vertrauens in König, Staat und Wirtschaft, Schuldentilgung sowie die Wiederingangsetzung des Geldkreislaufs, welche wiederum die Einstellung von Arbeitern ermöglicht

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Vertebrate odd-skipped related genes (Osr) have an essential function during the formation of the intermediate mesoderm (IM) and the kidney structures derived from it. Here, we show that these genes are also crucial for limb bud formation in the adjacent lateral plate mesoderm (LPM). Reduction of zebrafish Osr function impairs fin development by the failure of tbx5a maintenance in the developing pectoral fin bud. Osr morphant embryos show reduced wnt2b expression, and increasing Wnt signaling in Osr morphant embryos partially rescues tbx5a expression. Thus, Osr genes control limb bud development in a non-cell-autonomous manner, probably through the activation of Wnt2b. Finally, we demonstrate that Osr genes are downstream targets of retinoic acid (RA) signaling. Therefore, Osr genes act as a relay within the genetic cascade of fin bud formation: by controlling the expression of the signaling molecule Wnt2ba in the IM they play an essential function transmitting the RA signaling originated in the somites to the LPM.

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Three groups of Atlantic salmon were kept at a constant temperature of 4, 10 and 14 °C. The adipose fins were removed; six fish/group were sampled at 11 subsequent time points post-clipping. Samples were prepared for histopathological examination to study the course of re-epithelization. A score sheet was developed to assess the regeneration of epidermal and dermal cell types. Wounds were covered by a thin epidermal layer between 4 and 6 h post-clipping at 10 and 14 °C. In contrast, wound closure was completed between 6 and 12 h in fish held at a constant temperature of 4 °C. By 18 h post-clipping, superficial cells, cuboidal cells, prismatic basal cells and mucous cells were discernible in all temperature groups, rapidly progressing towards normal epidermal structure and thickness. Within the observation period, only minor regeneration was found in the dermal layers. A positive correlation between water temperature and healing rates was established for the epidermis. The rapid wound closure rate, epidermal normalization and the absence of inflammatory reaction signs suggest that adipose fin clipping under anaesthesia constitutes a minimally invasive method that may be used to mark large numbers of salmon presmolts without compromising fish welfare.