Avaliação de métodos de triagem e de detecção fenotípica de ß-lactamase de espectro ampliado (ESBL)

The catalytic function of extended-spectrum β-lactamases can result in high degrees of bacterial resistance to β-lactamic antimicrobials and in the emergence of ESBL among the members of Enterobacteriaceae family, especially Klebsiella pneumoniae and Escherichia coli. This occurs due to the dissemination and emergence of new variants of these enzymes caused by the high utilization of antibiotics like broad-spectrum cephalosporins. The ESBL are β-lactamases capable of conferring bacterial resistance to the penicillins, 1st, 2nd and 3rd generation cephalosporins, and aztreonam (but not cephamycins and carbapenems) through the hydrolysis of these antibiotics. In view of this phenomenon, the exact screening and detection of the producers of ESBL are essential for the appropriate selection of the antimicrobial therapy. The purposes of this study were to evaluate the best antimicrobial for the selection of ESBL producers and to determine the best method for the detection of such microorganisms. We evaluated 200 sequential bacterial samples including the species Klebsiella pneumoniae (56.5%), Escherichia coli (34%), Proteus mirabilis (8.5%) and Klebsiella oxytoca (1%), previously characterized as ESBL producers between February and September 2008 in the Laboratory of Microbiology, Botucatu Medical School - UNESP, Botucatu, São Paulo State, Brazil. To select the ESBL-producer bacteria, we used the disks recommended by CLSI 2008, aztreonam (ATM), cefpodoxime (CPD), ceftriaxone (CRO), cefotaxime (CTX) and ceftazidime (CAZ), besides cefepime (FEP). ESBL production was confirmed by three methods: double disk screening, ESBL Etest®, and Vitek® automated system. The disks employed in the double disk screening were: penicillin associated with β-lactamase inhibitor, amoxicillin-clavulanic acid, and two β-lactamic antibiotics, ceftazidime and cefotaxime...(Complete abstract click electronic access below)

Dinâmica de rotação de exoplanetas tipo terrestre com perturbação de terceiro corpo

In this work we study some topics of Celestial Mechanics, namely the problem of rigid body rotation and “spin-orbit” resonances. Emphasis is placed on the problem formulation and applications to some exoplanets with physical parameters (e.g. mass and radius) compatible with a terrestrial type constitution (e.g. rock) belonging to multiple planetary systems. The approach is both analytical and numerical. The analytical part consists of: i) the deduction of the equation of motion for the rotation problem of a spherical body with no symmetry, disturbed by a central body; ii) modeling the same problem by including a third-body in the planet-star system; iii) formulation of the concept of “spin-orbit” resonance in which the orbital period of the planet is an integer multiple of the rotation’s period. Topics of dynamical systems (e.g. equilibrium points, chaos, surface sections, etc.) will be included at this stage. In the numerical part simulations are performed with numerical models developed in the previous analytical section. As a first step we consider the orbit of the planet not perturbed by a third-body in the star-planet system. In this case the eccentricity and orbital semi-major axis of the planet are constants. Here the technique of surface sections, widely used in dynamical systems are applied. Next, we consider the action of a third body, developing a more realistic model for planetary rotation. The results in both cases are compared. Since the technique of disturbed surface sections is no longer applicable, we quantitatively evaluate the evolution of the characteristic angles of rotation (e.g. physical libration) by studying the evolution of individual orbits in the dynamically important regions of phase space, the latter obtained in the undisturbed case

Inclusão escolar de um aluno com autismo: descrevendo práticas de alfabetização em uma escola pública - ciclo I

Learning the written language has been the subject of research and study of various sciences in recent decades, in the same way that inclusion in regular education of students with disabilities such as autism, also has been the subject of discussions in the academic and even political. However, it can be observed that these two topics are disjointed, despite the importance of ownership of the system of writing by students with autism, because that would be a way to facilitate social interaction, which is the principal difficulty of this students. This research intend to describe the inclusion process of a student with autism into a common room of the initial years, in a public school, observing which are the strategies used by the teacher in the literacy process, as well as analyze the collaborative process developed by the researcher. The methodology was a qualitative and collaborative research, the kind of case study. The participants were a teacher and her students, from the cycle I of Primary School of a public school, among which, one is diagnosed with autism. The instruments used to the data’s analysis were interviews, with the teacher and the mother of the student with autism; the written productions of the student during the research; camp diary; and the observations made during the research. To the interventions, were used alternative practices, including material production (a mobile alphabet and a album of photos), that make more easy the process of literacy, The results showed the great difficulty in performing the interventions in a collaborative process, considering that in the observations, it was found that the practices of this teacher were traditional, and also there was no planning, on her part, content to be deal with the students. Otherwise, related to the development of the autism student’s written language, it could be seen like a breakthrough, have in...

Caracterização da contribuição da albumina para a formação do espectro de ressonância magnética nuclear (RMN) do plasma sanguíneo

The plasma represents a average of the information referring biochemists to the physiology of the organism as a whole, therefore it indirectly or directly interacts with all tissues of the body. In such a way the plasma can be considered as a metabolic “soup”. Using the Nuclear Magnetic Resonance Spectroscopy sanguineous plasma spectra had been generated and using deconvolution techniques it was possible to know the contribution of the albumin for the formation of the spectra of the sanguineous plasma

O pensamento psicanalítico sobre autismo a partir da análise da revista

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Um percurso pela psiquiatria infantil: dos antecedentes históricos à origem do conceito de autismo

This article is a conceptual study that aims to trace a historical course of the psychiatric knowledge about children, pointing how the conceptualization of autism will lead into this prospect. For such, we divided this work into three parts: the first is dedicated to the discussion of the concept of mental retardment, followed by the questioning of the first reflections on the psychoses of childhood and the birth of the Child Psychiatrist clinic and the conceptualization of autism by Psychiatry. Therefore, we seek to understand the meaning and origin of current practices, critically analyzing the psychiatric manuals and its impact on child psychopathology.

Eletrodinâmica quântica generalizada a la teoria de perturbação causal

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Teoria de perturbação causal para o modelo de Thirring como uma Teoria de Gauge

Pós-graduação em Física - IFT

Práticas pedagógicas inclusivas na educação infantil: atividades lúdicas envolvendo crianças com Transtorno do Espectro Autista (TEA)

Pós-graduação em Docência para a Educação Básica - FC

Autismo e família: revisão bibliográfica em bases de dados nacionais

Early studies involving childhood autism attributed to family involvement in impairment of psycho-emotional development of the child. The purpose of this study was to review the literature related to autism and family in two national databases (Theses Database of Capes and Scientific Electronic Library Online) without defining a specific period as well as identify the main thematic focused. Were located 29 studies in Theses Database of Capes, the first record in 1990 and 12 in Scientific Electronic Library Online, the first publication in 2001. The results were grouped into seven categories. The categories “Quality of Life” and “Family Relations” concentrate most of publications on Theses Database. Already in Scientific Electronic Library Online, mostly refers to the “Family Relations” and “literature review”. It was found that none of theses or dissertations was published in scientific paper format, hampering the dissemination of research in the area.

Espectro de gotas e potencial de deriva de caldas contendo o herbicida 2,4-d amina em misturas em tanque

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Associações entre borboletas frugívoras em áreas de floresta com diferentes históricos de perturbação antrópica

Pós-graduação em Ecologia e Biodiversidade - IBRC