Impact of a Potassium-enriched, Chloride-depleted 5% Glucose Solution on Gastrointestinal Function after Major Abdominopelvic Surgery: Results of a Randomized Controlled Trial.

BACKGROUND Gastrointestinal (GI) complications often delay recovery after radical cystectomy with urinary diversion. The authors investigated if perioperative administration of a potassium-enriched, chloride-depleted 5% glucose solution (G5K) accelerates recovery of GI function. METHODS This randomized, parallel-group, single-center double-blind trial included 44 consecutive patients undergoing radical cystectomy and pelvic lymph node dissection with urinary diversion. Patients were randomized to receive either a G5K (G5K group) solution or a Ringer's maleate solution (control group). Fluid management aimed for a zero fluid balance. Primary endpoint was time to first defecation. Secondary endpoints were time to normal GI function, need for electrolyte substitution, and renal dysfunction. RESULTS Time to first defecation was not significantly different between groups (G5K group, 93 h [19 to 168 h] and control group, 120 h [43 to 241 h]); estimator of the group difference, -16 (95% CI, -38 to 6); P = 0.173. Return of normal GI function occurred faster in the G5K group than in the control group (median, 138 h [range, 54 to 262 h] vs. 169 h [108 to 318 h]); estimator of the group difference, -38 (95% CI, -74 to -12); P = 0.004. Potassium and magnesium were less frequently substituted in the G5K group (13.6 vs. 54.5% [P = 0.010] and 18.2 vs. 77.3% [P < 0.001]), respectively. The incidence of renal dysfunction (Risk, Injury, Failure, Loss and End-stage kidney disease stage "risk") at discharge was 9.1% in the G5K group and 4.5% in the control group; P = 1.000. CONCLUSIONS Perioperative administration of a G5K did not enhance first defecation, but may accelerate recovery of normal GI function, and reduces potassium and magnesium substitution after radical cystectomy and urinary diversion.

Cost-effectiveness of topically applied fluorides /

Mode of access: Internet.

The electrical resistivity of lithium and sodium-potassium alloy /

"Contract AT(11-1)-229."

The electrical resistivity of sodium, potassium, rubidium and cesium in the liquid state /

"Contract AT(30-1)-2789."

The solubility of helium in lithium and potassium /

"Contract AT(30-1)-2789."

Magnesium fluorides, a literature search /

A literature search on "Magnesium Fluorides" from Chemical Abstracts and U.S.A.E.C. abstract services is presented.

Experimental results of forced convection boiling potassium heat transfer and pressure drop tests /

"Contract AT(30-1)-2789."

Forced convection boiling potassium experiments /

Work performed at CANEL.

International Workshop on Fluorides and Dental Caries Reductions : [proceedings] /

"Jointly sponsored by the Division of Dentistry, Bureau of Health Resources Development, Health Resources Administration, Department of Health, Education and Welfare, and the Department of Pedodontics, School of Dentistry, University of Maryland."

Neutron cross sections for titanium, potassium, magnesium, nitrogen, aluminum, silicon, sodium, oxygen, and manganese : final report covering the period 20 March, 1961 - 31 January, 1962 /

"For the U.S. Army Chemical Corps Nuclear Defense Laboratory"--Fore.

Carbonisation of seaweed as a preliminary to the extraction of iodine and potassium salts,

Mode of access: Internet.

Potassium metabolism in health and disease,

Mode of access: Internet.

Recherches physico-chimiques, faites sur la pile; sur la préparation chimique et les propriétés du potassium et du sodium; sur la décomposition de l'acide boracique; sur les acides fluorique, muriatique et muriatique oxigéné; sur l'action chimique de la lumière; sur l'analyse végétale et animale, etc.,

Mode of access: Internet.

A review of the patents and literature on the manufacture of potassium nitrate with notes on its occurrence and uses /

"July 1934."