Desenvolvimento do capim-marandu com altura fixa ou variável durante as estações do ano

Aimed to identify, for assessing the tillering dynamics and morphogenesis , strategy (s ) suitable ( s) defoliation management to optimize the appearance of tillers and biomass of Urochloa Brizantha syn. Brachiaria brizantha cv. Marandu ( marandugrass ) throughout the year. The experiment was conducted from January 2013 to May 2014 were studied three strategies defoliation: Marandugrass with 30 cm throughout the experimental period (constant height); Marandugrass 15 cm in winter, the spring 30 cm and 45 cm in summer (increasing height); and Marandugrass 45 cm in winter, the spring 30 cm and 15 cm in summer (descending height). The experimental design was completely randomized in a split plot in time, with four replications. In winter, in the spring and summer, the following variables were calculated: appearance rate (TApP), mortality (TMoP) and survival (TSoP) of tillers, balance (BAL) between TApP and TMoP, stability index (IE) numbers of tillers and leaf elongation rates and stem, length of leaf blade and stem, leaf senescence rate, phyllochron and duration of life of the sheet. The TAPP was higher in the early spring and summer. For TMoP, the highest values were in the late spring and summer. The balance between TApP and TMoP was negative in winter and late spring, regardless of defoliation strategy. There was no difference in IE between the heights of the canopy during winter and late spring .. The number of tillers was higher in early spring and summer and lower in winter and late spring. The defoliation strategies have not changed phyllochron, leaf elongation rate. In spring and summer, there were increases in the rates of appearance, elongation and leaf senescence and, furthermore, decreased life span and phyllochron sheet. The plant height with increasing showed a lower rate of senescence and lower culm length in the spring. To increase the number of tillers marandu, it is advantageous to handle the plant with increasing height, ie, 15 cm in autumn and winter, the spring 30 cm and 45 cm in summer.The maintaining of B. brizantha cv. Marandu with fixed height of 30 cm or with variations between 15 and 45cm from the fall/winter to summer, does not influence the appearance and the growth of leaves per tiller, which indicates great flexibility on management defoliation in this forage plant.

Project scoping for lessons learnt to apply to the Celtic Seas marine sub-region

This report involves a formal scoping exercise to identify lessons from a wide range of previous and current project and initiative experiences at the national, regional seas, European and global levels. An inventory of 77 projects and initiatives that are relevant with regard to the key activities proposed by the Celtic Seas Partnership has been compiled, as well as a short-list of 23 of the most pertinent projects, lessons learnt and contact names. This report has identified a number of synergies and collaborative opportunities from other project and initiatives in the Celtic Seas and beyond. It provides a strong starting point to clarify to stakeholders the uniqueness of the Celtic Seas Partnership project and delivers a sound baseline for the other preparatory actions (A2 Stakeholder Mapping and A3 Baseline Analysis for Marine Strategy Framework Directive Implementation) and the implementation actions. Furthermore, this report helps to avoid duplication of effort during the life-span of the project by highlighting what information pertaining to the Celtic Seas MSFD sub-region already exists.

The Excess Burden of Cytomegalovirus in African American Communities: A Geospatial Analysis.

Background.  Cytomegalovirus (CMV) is a common cause of birth defects and hearing loss in infants and opportunistic infections in the immunocompromised. Previous studies have found higher CMV seroprevalence rates among minorities and among persons with lower socioeconomic status. No studies have investigated the geographic distribution of CMV and its relationship to age, race, and poverty in the community. Methods.  We identified patients from 6 North Carolina counties who were tested in the Duke University Health System for CMV immunoglobulin G. We performed spatial statistical analyses to analyze the distributions of seropositive and seronegative individuals. Results.  Of 1884 subjects, 90% were either white or African American. Cytomegalovirus seropositivity was significantly more common among African Americans (73% vs 42%; odds ratio, 3.31; 95% confidence interval, 2.7-4.1), and this disparity persisted across the life span. We identified clusters of high and low CMV odds, both of which were largely explained by race. Clusters of high CMV odds were found in communities with high proportions of African Americans. Conclusions.  Cytomegalovirus seropositivity is geographically clustered, and its distribution is strongly determined by a community's racial composition. African American communities have high prevalence rates of CMV infection, and there may be a disparate burden of CMV-associated morbidity in these communities.

On the microstructure, growth pattern and original porosity of belemnite rostra: insights from calcitic Jurassic belemnites

Calcitic belemnite rostra are usually employed to perform paleoenvironmental studies based on geochemical data. However, several questions, such as their original porosity and microstructure, remain open, despite they are essential to make accurate interpretations based on geochemical analyses.This paper revisits and enlightens some of these questions. Petrographic data demonstrate that calcite crystals of the rostrum solidum of belemnites grow from spherulites that successively develop along the apical line, resulting in a “regular spherulithic prismatic” microstructure. Radially arranged calcite crystals emerge and diverge from the spherulites: towards the apex, crystals grow until a new spherulite is formed; towards the external walls of the rostrum, the crystals become progressively bigger and prismatic. Adjacent crystals slightly vary in their c-axis orientation, resulting in undulose extinction. Concentric growth layering develops at different scales and is superimposed and traversed by a radial pattern, which results in the micro-fibrous texture that is observed in the calcite crystals in the rostra.Petrographic data demonstrate that single calcite crystals in the rostra have a composite nature, which strongly suggests that the belemnite rostra were originally porous. Single crystals consistently comprise two distinct zones or sectors in optical continuity: 1) the inner zone is fluorescent, has relatively low optical relief under transmitted light (TL) microscopy, a dark-grey color under backscatter electron microscopy (BSEM), a commonly triangular shape, a “patchy” appearance and relatively high Mg and Na contents; 2) the outer sector is non-fluorescent, has relatively high optical relief under TL, a light-grey color under BSEM and low Mg and Na contents. The inner and fluorescent sectors are interpreted to have formed first as a product of biologically controlled mineralization during belemnite skeletal growth and the non-fluorescent outer sectors as overgrowths of the former, filling the intra- and inter-crystalline porosity. This question has important implications for making paleoenvironmental and/or paleoclimatic interpretations based on geochemical analyses of belemnite rostra.Finally, the petrographic features of composite calcite crystals in the rostra also suggest the non-classical crystallization of belemnite rostra, as previously suggested by other authors.

Inclusión digital de los estudiantes adultos que acceden a la universidad: análisis de sus actitudes y competencias digitales

Esta investigación se propone identificar las actitudes y competencias de los estudiantes adultos en relación con el uso de las TIC, con especial atención al uso de plataformas digitales de aprendizaje y redes sociales (Web 2.0). Asimismo, evalúa la incidencia de algunas variables sociodemográficas (género y edad) en el uso estas herramientas y en la autopercepción de los estudiantes sobre sus competencias digitales. Se ha realizado un estudio tipo encuesta con una muestra de 382 estudiantes que acceden a la Universidad de Sevilla a través de las vías establecidas para mayores de 25, de 40 y 45 años. Los resultados ponen de manifiesto una actitud generalmente positiva ante las TIC que puede calificarse como de pragmática, ya que estas herramientas se valoran positivamente en función de sus potenciales beneficios en los procesos de aprendizaje. Se constata a la vez que no han recibido formación específica en el uso de las TIC. El nivel de competencia que este alumnado percibe tener en el uso de estos recursos es medio-bajo. Además, el grupo de estudiantes mayores de 45 años se considera menos competente que los mayores de 25 y de 40 años. En consecuencia, se realizan algunas propuestas para mejorar la participación de los estudiantes maduros en la enseñanza universitaria.

Levensloopontwikkelingen in het Zelfbeeld van Hoogbegaafden: Een Kwalitatieve Studie

Zelfbeeldvorming is een levenslang proces en vindt plaats in de sociale context. Het zelfbeeld wordt gevormd op basis van zelfreflectie en sociale vergelijking en staat onder invloed van verschillende factoren. Het zelfbeeld is belangrijk voor de zelfregulatie en heeft invloed op het psychologisch welzijn. Door een asynchrone ontwikkeling wijkt de ontwikkeling van hoogbegaafden af van de gangbare patronen. Hoewel wordt gedacht dat hierdoor een adequate en positieve zelfbeeldvorming problematisch is, is hiernaar nauwelijks onderzoek gedaan. Dit kwalitatieve onderzoek is een eerste verkenning naar levensloopontwikkelingen in het zelfbeeld van personen die op volwassen leeftijd als hoogbegaafd zijn geïdentificeerd. De ontwikkelingen worden daarnaast in verband gebracht met het psychologisch welzijn. Acht personen, die op volwassen leeftijd als hoogbegaafd zijn geïdentificeerd, werden tijdens een diepte-interview uitgenodigd hun levensverhaal te vertellen. De levensverhalen werden geanalyseerd volgens een narratieve analysemethode. Levensloopontwikkelingen van hoogbegaafden in dit onderzoek kunnen het best kunnen worden begrepen vanuit het samenspel van de aan- en afwezigheid van belemmerende en bevorderende factoren, de kwaliteit van sociale interacties, individuele persoonskenmerken en de opeenstapeling van levenservaringen. In verschillende levensfasen staan zelfbeelden centraal die betrekking hebben op sociale rollen in de betreffende levensfase en de sociale eisen die daaruit voortvloeien. Variëteit hierin is afhankelijk is van de levensomstandigheden en de opeenstapeling van levenservaringen. Persoonlijke levenservaringen beïnvloeden de manier waarop men zichzelf begrijpt en naar zijn verleden, heden en toekomst kijkt. De betekenis die men geeft aan de eigen hoogbegaafdheid is afhankelijk van de mate van inadequatheid van het zelfbeeld vóór de identificatie en de persoonlijke opvatting over hoogbegaafdheid. Voor sommigen is de identificatie cruciaal voor de vorming van een adequaat zelfbeeld en een solide identiteitsvorming. Na de identificatie als hoogbegaafd staan zelfbeelden met betrekking tot persoonlijkheidskenmerken verbonden aan de hoogbegaafde identiteit, emotionaliteit en autonomie op de voorgrond. De mate waarin deze op de voorgrond treden is afhankelijk van de betekenis die men geeft aan de eigen hoogbegaafdheid. Bij alle deelnemers zijn zelfbeelden met betrekking tot de sociale interactie, zelfsturing, persoonlijke ontwikkeling en zelfontplooiing gedurende de gehele levensloop belangrijk. Onder invloed van veranderingen in het zelfbeeld gedurende de levensloop neemt het psychologisch welzijn toe op de domeinen zelfacceptatie, autonomie, grip op de omgeving en persoonlijke groei en voor een enkeling op het domein levensdoel. In verhouding tot deze welzijnsdomeinen neemt het welzijn op het domein positieve relaties met anderen matig toe. Dit heeft te maken met de onconventionaliteit van de deelnemers, waardoor men niet in de sociale context past en te maken heeft met (zelf)stigmatisering en een negatieve benadering door anderen.

Functions of the SLC36 transporter Pathetic in growth control of Drosophila sensory neurons

Thesis (Ph.D.)--University of Washington, 2016-08

Continuous acquisition of MHC:peptide complexes by recipient cells contributes to the generation of anti-graft CD8+T cell immunity

Understanding the evolution of the direct and indirect pathways of allorecognition following tissue transplantation is essential in the design of tolerance-promoting protocols. On the basis that donor bone marrow-derived antigen presenting cells are eliminated within days of transplantation, it has been argued that the indirect response represents the major threat to long term transplant survival, and is consequently the key target for regulation. However, the detection of MHC transfer between cells, and particularly the capture of MHC:peptide complexes by dendritic cells, led us to propose a third, semi-direct, pathway of MHC allorecognition. Persistence of this pathway would lead to sustained activation of direct pathway T cells, arguably persisting for the life of the transplant. In this study, we focused on the contribution of acquired MHC class I, on recipient DCs, during the life span of a skin graft. We observed that MHC class I acquisition by recipient DCs occurs for at least one month following transplantation and may be the main source of alloantigen that drives CD8+ cytotoxic T cell responses. In addition, acquired MHC class I-peptide complexes stimulate T cell responses in vivo further emphasizing the need to regulate both pathways to induce indefinite survival of the graft.

Population structure and growth of the hermit crab Pagurus brevidacylus (Anomura : Paguridae) from the northern coast of São Paulo, Brazil

The hermit crab Paguras brevidactylus (Crustacea: Anomura: Paguridea) from the infralittoral area of Anchieta Island, Ubatuba, was characterized by population Structure (size, sex ratio, reproduction and recruitment) and growth. Animals were collected monthly during 1999 by SCUBA diving. A total of 1525 individuals was collected (633 males and 892 females), 695 of them were ovigerous females. Overall sex ratio was 0.7:1 in favour of females. The crabs showed a unimodal distribution with males significantly larger than females. Ovigerous females were collected during all months and in high percentages from 1.0 mm of shield length, demonstrating intense and Continuous reproduction. The longevity was approximately 24 months for males and 18 for females, which showed larger growth rate and reached sexual maturity earlier (two months) than males. The low number of males in this Population may be due to the longer life span. Moreover, the sexual dimorphism favours males during the intra- and interspecific fights by shell, food, reproduction and territory. Females demonstrated a short life cycle and intense reproduction.

Influence of autogenous shrinkage on mass transport properties of concrete

La retracción autógena en el hormigón es el cambio volumétrico una vez iniciado su proceso de fraguado. Se desarrolla a edades muy tempranas debido a la retracción química y a la autodesecación. Éstos causan microfisuras en hormigones de alta resistencia y permiten el ingreso de agentes nocivos como dióxido de carbono, cloruros y sulfatos que deterioran al hormigón. A pesar de haber estudios de la retracción autógena, existe incertidumbre sobre su influencia en la durabilidad del hormigón. Por ello, el motivo del presente estudio es cuantificar y analizar el efecto de la retracción autógena en el hormigón usando tres pruebas de transporte: difusión de oxígeno, permeabilidad de oxígeno y absorción de agua. Dos métodos, para tres diferentes aglutinantes, fueron usados para determinar la mezcla control que produce menor retracción: utilizando SRA y realizando el curado en un cuarto de niebla. Posteriormente, los resultados de las pruebas de transporte entre la mezcla de control seleccionada y mezclas altamente afectadas por retracción autógena fueron comparados para diferentes aglutinantes. Resultados revelaron que muestras con SRA presentan menores retracciones autógenas y se sugiere que estas muestras sean consideradas de control. Se demostró que la retracción autógena afecta significativamente los coeficientes de transporte los cuales en un punto de vista de servicio pueden reducir la vida útil de cualquier estructura realizada con hormigón de alta resistencia. Esta investigación además confirmó que la mayor deformación autógena ocurre durante las dos primeras semanas; por lo tanto, se debe tomar cuidado suficiente en el curado.

Antitumor activity of doxorubicine-loaded nanoemulsion against Ehrlich ascites carcinoma-bearing mice

Purpose: To evaluate the antitumor activity of doxorubicine (DOX)-loaded nanoemulsion (NE) on Ehrlich ascites carcinoma (EAC)-bearing Swiss albino mice. Methods: The mice were divided into five groups (n = 20) according to the administered drug. Groups I - V were labeled as negative control (normal), positive control of the untreated EAC bearing mice (EAC control), blank nanoemulsion (BI-NE), DOX-loaded-NE (DOX/LNE) and free DOX (DOX-Sol), respectively. Cardiotoxicity was assessed by measuring changes in body and organ weight, analyzing serum enzymes and lipids, and examining histological changes in heart tissues by light microscopy. In addition, mean survival time (MST), increase in life span (ILS) and survival (S) of the mice were determined. Results: DOX/LNE group reduced levels of serum enzymes and lowered damage to heart tissues relative to DOX-Sol group. The MST of the DOX/LNE group (80 ± 0.0 days) was significantly greater than that for DOX-Sol group (34.6 ± 8.9 days), while ILS of DOX/LNE (265.30 days) was higher than that of DOX-Sol (57.99 days) by 4.6-fold. Conclusion: Administration of DOX/LNE to EAC-bearing mice improves the efficacy of DOX and reduce its side effects on the heart.

Natural plant polyphenols for alleviating oxidative damage in man: Current status and future perspectives

The balance between oxidation and reduction is important for maintaining a healthy biological system. Oxidative stress results from an imbalance between excessive formation of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS) and limited endogenous defense systems, and this imbalance can adversely alter lipids, proteins and DNA, causing a number of human diseases. Thus, exogenous antioxidants that can neutralize the effect of free radicals are needed to diminish the cumulative effects of oxidative damage over human life span. Current research reveals that phenolic compounds in plants possess high antioxidant activity and free radical scavenging capacity and can prevent the body from oxidative damage over human life span. This review focuses on the present understanding of free radicals and antioxidants and their importance in human health and disease. Information about the chemical features of free radicals as well as their deleterious effects on cell structures is reviewed. The chemical structure and anti-oxidative mechanisms of essential polyphenols and their potential health benefits are presented. In addition, the limitation of natural antioxidants and a perspective on likely future trends in this field are also discussed.

Leakage Temperature Dependency Aware Real-Time Scheduling for Power and Thermal Optimization

Catering to society’s demand for high performance computing, billions of transistors are now integrated on IC chips to deliver unprecedented performances. With increasing transistor density, the power consumption/density is growing exponentially. The increasing power consumption directly translates to the high chip temperature, which not only raises the packaging/cooling costs, but also degrades the performance/reliability and life span of the computing systems. Moreover, high chip temperature also greatly increases the leakage power consumption, which is becoming more and more significant with the continuous scaling of the transistor size. As the semiconductor industry continues to evolve, power and thermal challenges have become the most critical challenges in the design of new generations of computing systems. In this dissertation, we addressed the power/thermal issues from the system-level perspective. Specifically, we sought to employ real-time scheduling methods to optimize the power/thermal efficiency of the real-time computing systems, with leakage/ temperature dependency taken into consideration. In our research, we first explored the fundamental principles on how to employ dynamic voltage scaling (DVS) techniques to reduce the peak operating temperature when running a real-time application on a single core platform. We further proposed a novel real-time scheduling method, “M-Oscillations” to reduce the peak temperature when scheduling a hard real-time periodic task set. We also developed three checking methods to guarantee the feasibility of a periodic real-time schedule under peak temperature constraint. We further extended our research from single core platform to multi-core platform. We investigated the energy estimation problem on the multi-core platforms and developed a light weight and accurate method to calculate the energy consumption for a given voltage schedule on a multi-core platform. Finally, we concluded the dissertation with elaborated discussions of future extensions of our research.

Optimization of Wireless Power Transfer via Magnetic Resonance in Different Media

A wide range of non-destructive testing (NDT) methods for the monitoring the health of concrete structure has been studied for several years. The recent rapid evolution of wireless sensor network (WSN) technologies has resulted in the development of sensing elements that can be embedded in concrete, to monitor the health of infrastructure, collect and report valuable related data. The monitoring system can potentially decrease the high installation time and reduce maintenance cost associated with wired monitoring systems. The monitoring sensors need to operate for a long period of time, but sensors batteries have a finite life span. Hence, novel wireless powering methods must be devised. The optimization of wireless power transfer via Strongly Coupled Magnetic Resonance (SCMR) to sensors embedded in concrete is studied here. First, we analytically derive the optimal geometric parameters for transmission of power in the air. This specifically leads to the identification of the local and global optimization parameters and conditions, it was validated through electromagnetic simulations. Second, the optimum conditions were employed in the model for propagation of energy through plain and reinforced concrete at different humidity conditions, and frequencies with extended Debye's model. This analysis leads to the conclusion that SCMR can be used to efficiently power sensors in plain and reinforced concrete at different humidity levels and depth, also validated through electromagnetic simulations. The optimization of wireless power transmission via SMCR to Wearable and Implantable Medical Device (WIMD) are also explored. The optimum conditions from the analytics were used in the model for propagation of energy through different human tissues. This analysis shows that SCMR can be used to efficiently transfer power to sensors in human tissue without overheating through electromagnetic simulations, as excessive power might result in overheating of the tissue. Standard SCMR is sensitive to misalignment; both 2-loops and 3-loops SCMR with misalignment-insensitive performances are presented. The power transfer efficiencies above 50% was achieved over the complete misalignment range of 0°-90° and dramatically better than typical SCMR with efficiencies less than 10% in extreme misalignment topologies.

Structural Data Acquisition Using Sensor Network

The development cost of any civil infrastructure is very high; during its life span, the civil structure undergoes a lot of physical loads and environmental effects which damage the structure. Failing to identify this damage at an early stage may result in severe property loss and may become a potential threat to people and the environment. Thus, there is a need to develop effective damage detection techniques to ensure the safety and integrity of the structure. One of the Structural Health Monitoring methods to evaluate a structure is by using statistical analysis. In this study, a civil structure measuring 8 feet in length, 3 feet in diameter, embedded with thermocouple sensors at 4 different levels is analyzed under controlled and variable conditions. With the help of statistical analysis, possible damage to the structure was analyzed. The analysis could detect the structural defects at various levels of the structure.