945 resultados para Information-Analytical System


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Breve reseña del archivo de autoridad de autores institucionales del Sistema de Información para el Caribe en Materia de Planificación Económica y Social.

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Includes bibliography

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Evalua las operaciones y eficiencia del servicio de informaciones de la CEPAL en Santiago. Recomienda medidas practicas para reforzar las comunicaciones internas y externas de la CEPAL, llegar mas a conocimiento del publico, y elevar la imagen de la institucion en America Latina, el Caribe, Estados Unidos y Europa.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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The wide variety of molecular architectures used in sensors and biosensors and the large amount of data generated with some principles of detection have motivated the use of computational methods, such as information visualization techniques, not only to handle the data but also to optimize sensing performance. In this study, we combine projection techniques with micro-Raman scattering and atomic force microscopy (AFM) to address critical issues related to practical applications of electronic tongues (e-tongues) based on impedance spectroscopy. Experimentally, we used sensing units made with thin films of a perylene derivative (AzoPTCD acronym), coating Pt interdigitated electrodes, to detect CuCl(2) (Cu(2+)), methylene blue (MB), and saccharose in aqueous solutions, which were selected due to their distinct molecular sizes and ionic character in solution. The AzoPTCD films were deposited from monolayers to 120 nm via Langmuir-Blodgett (LB) and physical vapor deposition (PVD) techniques. Because the main aspects investigated were how the interdigitated electrodes are coated by thin films (architecture on e-tongue) and the film thickness, we decided to employ the same material for all sensing units. The capacitance data were projected into a 2D plot using the force scheme method, from which we could infer that at low analyte concentrations the electrical response of the units was determined by the film thickness. Concentrations at 10 mu M or higher could be distinguished with thinner films tens of nanometers at most-which could withstand the impedance measurements, and without causing significant changes in the Raman signal for the AzoPTCD film-forming molecules. The sensitivity to the analytes appears to be related to adsorption on the film surface, as inferred from Raman spectroscopy data using MB as analyte and from the multidimensional projections. The analysis of the results presented may serve as a new route to select materials and molecular architectures for novel sensors and biosensors, in addition to suggesting ways to unravel the mechanisms behind the high sensitivity obtained in various sensors.

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[EN]This paper describes a wildfi re forecasting application based on a 3D virtual environment and a fi re simulation engine. A novel open source framework is presented for the development of 3D graphics applications over large geographic areas, off ering high performance 3D visualization and powerful interaction tools for the Geographic Information Systems (GIS) community. The application includes a remote module that allows simultaneous connection of several users for monitoring a real wildfi re event.

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During recent years a consistent number of central nervous system (CNS) drugs have been approved and introduced on the market for the treatment of many psychiatric and neurological disorders, including psychosis, depression, Parkinson disease and epilepsy. Despite the great advancements obtained in the treatment of CNS diseases/disorders, partial response to therapy or treatment failure are frequent, at least in part due to poor compliance, but also genetic variability in the metabolism of psychotropic agents or polypharmacy, which may lead to sub-therapeutic or toxic plasma levels of the drugs, and finally inefficacy of the treatment or adverse/toxic effects. With the aim of improving the treatment, reducing toxic/side effects and patient hospitalisation, Therapeutic Drug Monitoring (TDM) is certainly useful, allowing for a personalisation of the therapy. Reliable analytical methods are required to determine the plasma levels of psychotropic drugs, which are often present at low concentrations (tens or hundreds of nanograms per millilitre). The present PhD Thesis has focused on the development of analytical methods for the determination of CNS drugs in biological fluids, including antidepressants (sertraline and duloxetine), antipsychotics (aripiprazole), antiepileptics (vigabatrin and topiramate) and antiparkinsons (pramipexole). Innovative methods based on liquid chromatography or capillary electrophoresis coupled to diode-array or laser-induced fluorescence detectors have been developed, together with the suitable sample pre-treatment for interference removal and fluorescent labelling in case of LIF detection. All methods have been validated according to official guidelines and applied to the analysis of real samples obtained from patients, resulting suitable for the TDM of psychotropic drugs.

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Capire come ottenere l'informazione accessibile, cioè quanta informazione classica si può estrarre da un processo quantistico, è una delle questioni più intricate e affascinanti nell'ambito della teoria dell'informazione quantistica. Nonostante l'importanza della nozione di informazione accessibile non esistono metodi generali per poterla calcolare, esistono soltanto dei limiti, i più famosi dei quali sono il limite superiore di Holevo e il limite inferiore di Josza-Robb-Wootters. La seguente tesi fa riferimento a un processo che coinvolge due parti, Alice e Bob, che condividono due qubits. Si considera il caso in cui Bob effettua misure binarie sul suo qubit e quindi indirizza lo stato del qubit di Alice in due possibili stati. L'obiettivo di Alice è effettuare la misura ottimale nell'ottica di decretare in quale dei due stati si trova il suo qubit. Lo strumento scelto per studiare questo processo va sotto il nome di 'quantum steering ellipsoids formalism'. Esso afferma che lo stato di un sistema di due qubit può essere descritto dai vettori di Bloch di Alice e Bob e da un ellissoide nella sfera di Bloch di Alice generato da tutte le possibili misure di Bob. Tra tutti gli stati descritti da ellissoidi ce ne sono alcuni che manifestano particolari proprietà, per esempio gli stati di massimo volume. Considerando stati di massimo volume e misure binarie si è riuscito a trovare un limite inferiore all'informazione accessibile per un sistema di due qubit migliore del limite inferiore di Josza-Robb-Wootters. Un altro risultato notevole e inaspettato è che l'intuitiva e giustificata relazione 'distanza tra i punti nell'ellissoide - mutua informazione' non vale quando si confrontano coppie di punti ''vicine'' tra loro e lontane dai più distanti.