Informe de la Segunda Reunión del Comité Examinador del Comité de Desarrollo y Cooperación del Caribe (CDCC), Puerto España, 20 febrero 1986 = Report of the Second Meeting of the Review Committee of the Caribbean Development and Co-operation Committee (CDCC), Port-of-Spain, 20 February 1986 = Rapport de la Deuxième Réunion du Comité d'Examen du CDCC, Port-of-Spain, 20 février 1986

Informe de la reunion que tuvo por objetivo principal examinar las actividades de los organismos especializados y otros organos en relacion con el programa de trabajo del CDCC en lo que concierne a la coordinacion del programa.

Synthesis, characterization, x-ray structure, DNA cleavage, and cytotoxic activities of palladium(ii) complexes of 4-phenyl-3-thiosemicarbazide and triphenylphosphane

Complexes of the type [PdX(PPh3)(1)]X [1 = 4-phenyl-3- thiosemicarbazide; X = Cl- (2), Br- (3), I- (4), and SCN- (5)] have been synthesized and characterized by elemental analyses and IR, UV/Vis, and 1H and 13C NMR spectroscopy. The molecular structure of complex 4 was determined by single-crystal X-ray diffraction. The binding of the complexes with a purine base (guanosine) was investigated by 1H NMR spectroscopy and mass spectrometry, which showed the complexes to coordinate to guanosine through N7. A gel electrophoresis assay demonstrated the ability of 2-5 to cleave DNA plasmid. All the complexes were tested in vitro by means of the MTT assay for their cytotoxicity against two murine cell lines, LM3 (mammary adenocarcinoma) and LP07 (lung adenocarcinoma), and compared with cisplatin. Complexes 2-5 exhibited good cytotoxicity that surpasses that of cisplatin in the case of LM3. A series of thiosemicarbazide/phosphane palladium(II) complexes have been synthesized and fully characterized. These complexes are able to cleave DNA plasmid and show cytotoxicity against adenocarcinoma (mammary LM3 and lung LP07), surpassing the cytotoxicity of cisplatin in the case of LM3. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Training Seminar on Community Participation Methodology (I), Port-of-Spain, 29 March 1984

Includes bibliography

Urban management in medium-sized cities: final report of the case study Port-of-Spain, Trinidad and Tobago

Includes bibliography

A Municipal Information System for Port of Spain, Trinidad and Tobago

Includes bibliography