8-8-19, Deauville [une baigneuse] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55375

8/7/19 St François de Sales. Emmanuel Derode avec Melle Thiery[-Cherer] de Cabanes : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 54781

Islet-brain1/C-Jun N-terminal kinase interacting protein-1 (IB1/JIP-1) promoter variant is associated with Alzheimer's disease.

Islet-brain1 (IB1) or c-Jun NH2 terminal kinase interacting protein-1 (JIP-1), the product of the MAPK8IP1 gene, functions as a neuronal scaffold protein to allow signalling specificity. IB1/JIP-1 interacts with many cellular components including the reelin receptor ApoER2, the low-density lipoprotein receptor-related protein (LRP), kinesin and the Alzheimer's amyloid precursor protein. Coexpression of IB1/JIP-1 with other components of the c-Jun NH2 terminal-kinase (JNK) pathway activates the JNK activity; conversely, selective disruption of IB1/JIP-1 in mice reduces the stress-induced apoptosis of neuronal cells. We therefore hypothesized that IB1/JIP-1 is a risk factor for Alzheimer's disease (AD). By immunocytochemistry, we first colocalized the presence of IB1/JIP-1 with JNK and phosphorylated tau in neurofibrillary tangles. We next identified a -499A>G polymorphism in the 5' regulatory region of the MAPK8IP1 gene. In two separate French populations the -499A>G polymorphism of MAPK8IP1 was not associated with an increased risk to AD. However, when stratified on the +766C>T polymorphism of exon 3 of the LRP gene, the IB1/JIP-1 polymorphism was strongly associated with AD in subjects bearing the CC genotype in the LRP gene. The functional consequences of the -499A>G polymorphism of MAPK8IP1 was investigated in vitro. In neuronal cells, the G allele increased transcriptional activity and was associated with an enhanced binding activity. Taken together, these data indicate that the increased transcriptional activity in the presence of the G allele of MAPK8IP1 is a risk factor to the onset of in patients bearing the CC genotype of the LRP gene.

10-8-19, Deauville [promeneurs] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55422

13-8-19, la vie chère aux halles [de Paris] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55435

Prévoir les performances individuelles des auditeurs assistants. Résultats d'une étude empirique conduite en Suisse. L'Expert-comptable suisse 10/8 p. 487-493.

Les auditeurs exercent une activité tournée dans une large mesure vers l'intérêt public. Il paraît donc important que la qualité des services qu'ils fournissent soit aussi élevée que possible. La question se pose dès lors de savoir s'il est possible, notamment au moment de leur engagement, de prévoir les performances individuelles futures des auditeurs.

A study of personality in children aged 8-12 years: Comparing self- and partents' ratings

This study was designed to investigate personality development with children aged 8 to 12. For this purpose, Children's self-perceptions were compared to parent's ratings. 506 children and their parents completed a selection of 38 questions from the Hierarchical Personality Inventory for Children (HiPIC). Results showed an age-related increase in the structural congruence of children's ratings compared to parents' ratings and a highly significant increase in the reliabilities of both parents' and children's assessments. The mean correlation between the children's self-descriptions and parents' ratings were higher for Conscientiousness and Imagination than for Extraversion, Benevolence and Emotional Stability and significantly increased with the children's age. Mean-levels decreased with age for Imagination in parents' ratings and for Benevolence, Conscientiousness, and Imagination, in children's ratings. This study showed that personality development from 8 to 12 years goes along with an increase in the agreement between the children's self-perceptions and the parents' perceptions of the children's personality.

Bronchiolite respiratoire et bronchiolite respiratoire avec pneumopathie interstitielle [Respiratory bronchiolitis and respiratory bronchiolitis-associated interstitial lung disease].

The increasing use of chest CT imaging in medical practice rises the likelihood of the general practitioner to be confronted with cases of interstitial lung disease. Respiratory bronchiolitis (RB) and respiratory bronchiolitis-associated interstitial lung disease (RB-ILD) are two smoking-related lung damages that may have important implications for the patient's management. The authors present in this paper a review of current knowledge of the epidemiology, clinical features, prognosis, and treatment options of RB and RB-ILD.

Contribution à une étude normative de l'épreuve de Rorschach auprès d'un groupe d'enfants de 8 à 14 ans non-consultants

Cette étude normative de l'épreuve de Rorschach porte sur une population suisse de 102 enfants et adolescents non-consultants de 8 à 14 ans, répartis par tranches d'âge, sexe et niveau intellectuel. Elle présente un aperçu des différentes méthodes utilisées dans l'interprétation du Rorschach et des normes francophones existantes. Une réflexion est aussi proposée autour de la question de l'utilité de l'analyse des facteurs quantitatifs au Rorschach. Suite à une présentation détaillée de la méthodologie de recherche, les résultats sont exposés et comparés aux normes antérieures. Ils ne révèlent pas de différences importantes avec ces dernières, à l'exception de la hausse du F%, de la baisse du F+% et du nombre de Banalités. Les comparaisons Age, Sexe et QI révèlent quelques différences entre les groupes.

8-8-19, Deauville [enfants jouant sur la plage] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55361

8-8-19, Deauville [groupe de baigneurs encadrés par des cordes] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55360

8-8-19, Deauville [enfants jouant dans l'eau] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 55362