[Lettre autographe signée de Giuseppe Verdi à Escudier (sans lieu), (16 août 1867)]

Comprend aussi une enveloppe

[Lettre autographe signée de Giuseppe Verdi adressée à Escudier, Naples, 16 novembre 1872]

Comprend aussi une enveloppe

EPI Update, April 16, 2010

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Iowa Workforce Monthly, May 2010, Issue 16

Highlights: * On Wednesday, April 7th, the Marshalltown Workforce Center and the local New Iowan Center participated in the regional Central Iowa Job Fair.....pg. 2 * The Burlington Workforce Center had a successful year offering Iowans free income tax assistance through the Volunteer Income Tax Assistance (VITA) program.............................................pg. 2 * The New Iowan Center and the Muscatine Workforce Center will be holding a Spring Career Fair on Thursday, May 20th.......pg. 2 * Iowans gathered Wednesday, April 28, to pay tribute and to reflect upon the lives of the Iowa workers who lost their lives in 2009 while at work............................pg. 3

Infonet, January 16, 2009, Issue

A publication of the Governorʼs DD Council & ID Action. It was first created nearly two decades ago as a print-only publication, sent to a few hundred people. Today we offer our nearly 3,000 direct subscribers and a variety of services.

Motor Vehicle Crash Fatalities for Week Ending, July 16, 2010

Motor Vehicle Crash Fatalities

EPI Update, July 16, 2010

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Secure and Prepared Newsletter, August 26, 2010, Vol. 6, no. 16

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management

Mucosal but not parenteral immunization with purified human papillomavirus type 16 virus-like particles induces neutralizing titers of antibodies throughout the estrous cycle of mice.

We have recently shown that nasal immunization of anesthetized mice with human papillomavirus type 16 (HPV16) virus-like particles (VLPs) is highly effective at inducing both neutralizing immunoglobulin A (IgA) and IgG in genital secretions, while parenteral immunization induced only neutralizing IgG. Our data also demonstrated that both isotypes are similarly neutralizing according to an in vitro pseudotyped neutralization assay. However, it is known that various amounts of IgA and IgG are produced in genital secretions along the estrous cycle. Therefore, we have investigated how this variation influences the amount of HPV16 neutralizing antibodies induced after immunization with VLPs. We have compared parenteral and nasal protocols of vaccination with daily samplings of genital secretions of mice. Enzyme-linked immunosorbent assay analysis showed that total IgA and IgG inversely varied along the estrous cycle, with the largest amounts of IgA in proestrus-estrus and the largest amount of IgG in diestrus. This resulted in HPV16 neutralizing titers of IgG only being achieved during diestrus upon parenteral immunization. In contrast, nasal vaccination induced neutralizing titers of IgA plus IgG throughout the estrous cycle, as confirmed by in vitro pseudotyped neutralization assays. Our data suggest that mucosal immunization might be more efficient than parenteral immunization at inducing continuous protection of the female genital tract.

Secular trends in legal and illegal substance use among 16 to 20 year old adolescents in Switzerland.

BACKGROUND: Data targeting trends in legal and illegal substance use by adolescents are scarce. Using the data from two similar large national surveys run in 1993 and 2002, this paper assesses secular trends in rates of substance use among 16-20-year-old Swiss adolescents. METHODS: Self-reported regular use of tobacco, alcohol misuse, regular cannabis use (01 occasion over last 30 days) and lifetime use of psychoactive medication, LSD, ecstasy, cocaine and heroine were assessed through identical questions using an anonymous self-administered questionnaire. 9268 (1993) and 7428 (2002) high school students and apprentices were included in the analyses. RESULTS: There is a higher proportion of regular smokers among apprentices than among students (p <0.001). Between 1993 and 2002 the increase in regular tobacco consumption was significant among both female and male apprentices (p <0.001) but not among students. Between 1993 and 2002 alcohol misuse significantly increased in all four groups (p <0.001). It is more prevalent among males than among females (p <0.001) and higher among apprentices than among students (p <0.001). Regular use of cannabis has increased in the four groups (p <0.0001). It is higher among males than among females (p <0.001), while it is largely the same among students and apprentices. While the increase in ecstasy use is highly significant in all four groups (p <0.001), the increase in LSD and cocaine use is significant among apprentices only (p <0.001). Use of LSD, ecstasy and cocaine is more prevalent among males than among females (<0.001) and higher among apprentices than among students (p <0.001). CONCLUSION: The secular increase in psychoactive substance use among older Swiss adolescents calls for the implementation of effective strategies both from individual and public health viewpoints.

Secure and Prepared Newsletter, December 16, 2010, Vol. 6, no. 24

A bi-weekly newsletter for those involved in the fields of homeland security and/or emergency management