Epidemiology of uveitis in children over a 10-year period.

OBJECTIVES: The aim of the present study is to investigate the demographics, aetiologies, complications, treatments and visual outcomes in paediatric uveitis patients in the French-speaking part of Switzerland. METHODS: Chart review of all patients diagnosed with uveitis before the age of 16 years, presenting to two tertiary referral centres (uveitis and paediatric rheumatology clinics) in Lausanne, Switzerland, between 2000 and 2009. RESULTS: Seventy-nine children (37 girls) were identified, 62 living in Switzerland, 15 in Europe and 2 in North Africa. Median age at first symptoms was 9.0 years (range 1.5-15.8 years), with a median follow-up time of 1.8 years (0-8 years). Both eyes were involved in 51 patients (64.6%). The course was acute in 30.4%, chronic in 60.8% and recurrent in 8.9%. Anterior uveitis occurred in 39.2%, intermediate in 32.9%, posterior in 22.8% and panuveitis in 5.1%. The three main diagnoses were idiopathic uveitis (34.2%), JIA-related uveitis (22.8%) and toxoplasmic retinochoroiditis (15.2%). During the last follow-up visit, the visual acuity (VA) was ≥8/10 in 72% of all eyes with a measurable VA. Cataract (8%), ocular hypertension/glaucoma (8%) and macular fibrosis (4%) were the three most common severe complications. Systemic steroids were given to 56% and biological agents to 24% of patients with inflammatory uveitis. CONCLUSIONS: Uveitis in children can be a devastating disease. A strict classification of aetiologies and a tight collaboration between paediatric rheumatologists and ophthalmologists are important to ensure early control of ocular inflammation and improve long-term visual prognosis.

10

The stable isotope composition of ostracod fossils is useful for palaeoenvironmental reconstruction. Laboratory as well as 'natural environment' cultures demonstrate that the carbon and oxygen isotope compositions of ostracod shells faithfully record the environmental conditions at the time of valve precipitation. Oxygen isotope composition of ostracod calcite reflects the composition and temperature of the host water, but ostracod shells are enriched in 18O compared to the value expected for inorganic calcite precipitating under equilibrium under the same conditions. This 'vital effect' is generally constant for closely related species and equals 1.5 to 3 0/00 for Candoninae, 0 to 2.5 0/00 for Cyprididae and 0.8 to 1.5 0/00 for Cytheroidea. The carbon isotope composition of ostracod calcite is controlled by a complex interaction between the ecology of the species and environmental parameters. Previous natural environmental studies suggest that many (but not all) taxa crystallize their shells in or very close to equilibrium with the carbon isotope composition of dissolved inorganic carbon, and that the composition of littoral, epifaunal species reflects seasonal variation in the carbon isotope composition of dissolved inorganic carbon of bottom water according to their life cycles, while that of deep-water, infaunal species reflects the variation interstitial pore water according to microhabitat preferences.

Lottery Action, September 8-21, 2003, Vol. 10, no. 18

Newsletter for Iowa Lottery

Lottery Action, August 25-September 7, 2003, Vol. 10, no. 17

Iowa Lottery Authority Retailer Information Newsletter

Lottery Action, August 11-24, 2003, Vol. 10 no. 16

Iowa Lottery Authority Retailer Information Newsletter

Lottery Action, July 28-August 10, 2003, Vol. 10 no. 15

Newsletter for Iowa Lottery.

Lottery Action, July 14-27, 2003, Vol. 10, no. 14

Newsletter for Iowa Lottery.

Lottery Action, June 30-July 13, 2003, Vol. 10, no. 13

Newsletter for Iowa Lottery

Lottery Action, June 16-29, 2003, Vol. 10, no. 12

Newsletter for Iowa Lottery

Lottery Action, June 2-15, 2003, Vol. 10, no. 11

Newsletter for Iowa Lottery

Lottery Action, May 19-June 1, 2003, Vol. 10, no. 10

Newsletter for Iowa Lottery

Lottery Action, May 5-18, 2003, Vol. 10, no. 9

Newsletter for Iowa Lottery

Lottery Action, April 21-May 4, 2003, Vol. 10, no. 8

Iowa Lottery Authority Retailer Information Newsletter

Lottery Action, April 7-20, 2003, Vol. 10, no. 7

Iowa Lottery Authority Retailer Information Newsletter

Lottery Action, March 24-April 6, 2003, Vol. 10, no. 6

Newsletter for Iowa Lottery