La trigonometrie rectiligne et spherique ou il est Traite de la construction des tables de sinus, tangentes, secantes et logarithmes : de l'usage de ces tables pour la résolution des triangles avec des questions astronomiques, & ces mêmes tables tres - exactement calculées sur un rayon de 10000000 parties /

Mode of access: Internet.

Cours de mathematique : qui comprend toutes les parties les plus utiles & les plus necessaires à un homme de guerre ... : tome second qui contient l'arithmetique, la trigonometrie, & les tables de sinus /

Mode of access: Internet.

Analysis of some cloud and frontal events : recorded during the Boulder Upslope Cloud Observation Experiment (BUCOE) of 1982 /

"March 1984."

Die Logarithmen der Sinus und Tangenten für 0⁰ bis 5⁰ und der Cosinus und Contangenten für 85⁰ bis 90⁰ von tausendstel zu tausendstel grad. : als ergänzung zu C. Bremiker's 5stelligen Logarithmentafeln /

Mode of access: Internet.

Tables de logarithmes à huit décimales des nombres entiers de 1 à 120 000 et des sinus et tangentes de dix secondes en dix secondes d'arc dans le système de la division centésimale du quadrant.

At head of title: Service géographique de l'Armée.

Trigonometrische Tafeln, darin die Sinus und Tangenten für jede Minute des Quadranten, nebst ihren Logarithmen, und den Logarithmen der gemeinen Zahlen von 1 bis 10000 wie auch die Quadrat- und Kubilszahlen von 1 bis 1000 enthalten sind ...

Mode of access: Internet.

Opus palatinum. Sinus- und Cosinus-Tafeln von 10" zu 10".

Mode of access: Internet.

Tables trigonométriques décimales, ou Table des logarithmes des sinus, sécantes et tangentes, suivant la division du quart de cercle en 100 degrés, du degré en 100 minutes, et de la minute en 100 secondes; précédées de la table des logarithmes des nombres depuis dix mille jusqu'à cent mille, et de plusieurs tables subsidiaires: calculées par Ch. Borda, rev., augm., et pub. par J. B. J. Delambre.

Mode of access: Internet.

On the functions of the cerebrum; the frontal lobes.

Mode of access: Internet.

Chase S. Osborn, frontal portrait ca. 1898

see inscriptions and label on portrait from same studio session, na18169

Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics

The molecular processes underlying alcohol dependence are not fully understood. Many characteristic behaviours result from neuroadaptations in the mesocorticolimbic system. In addition, alcoholism is associated with a distinct neuropathology. To elucidate the molecular basis of these features, we compared the RNA expression profile of the nucleus accumbens and prefrontal cortex of human brain from matched individual alcoholic and control cases using cDNA microarrays. Approximately 6% of genes with a marked alcohol response were common to the two brain regions. Alcohol-responsive genes were grouped into 11 functional categories. Predominant alcohol-responsive genes in the prefrontal cortex were those encoding DNA-binding proteins including transcription factors and repair proteins. There was also a down-regulation of genes encoding mitochondrial proteins, which could result in disrupted mitochondrial function and energy production leading to oxidative stress. Other alcohol-responsive genes in the prefrontal cortex were associated with neuroprotection/apoptosis. In contrast, in the nucleus accumbens, alcohol-responsive genes were associated with vesicle formation and regulation of cell architecture, which suggests a neuroadaptation to chronic alcohol exposure at the level of synaptic structure and function. Our data are in keeping with the previously reported alcoholism-related pathology characteristic of the prefrontal cortex, but suggest a persistent decrease in neurotransmission and changes in plasticity in the nucleus accumbens of the alcoholic.

Patterns of gene expression in the frontal cortex discriminate alcoholic from non-alcoholic individuals

Alcohol dependence is characterized by tolerance, physical dependence, and craving. The neuroadaptations underlying these effects of chronic alcohol abuse are likely due to altered gene expression. Previous gene expression studies using human post-mortem brain demonstrated that several gene families were altered by alcohol abuse. However, most of these changes in gene expression were small. It is not clear if gene expression profiles have sufficient power to discriminate control from alcoholic individuals and how consistent gene expression changes are when a relatively large sample size is examined. In the present study, microarray analysis (similar to 47 000 elements) was performed on the superior frontal cortex of 27 individual human cases ( 14 well characterized alcoholics and 13 matched controls). A partial least squares statistical procedure was applied to identify genes with altered expression levels in alcoholics. We found that genes involved in myelination, ubiquitination, apoptosis, cell adhesion, neurogenesis, and neural disease showed altered expression levels. Importantly, genes involved in neurodegenerative diseases such as Alzheimer's disease were significantly altered suggesting a link between alcoholism and other neurodegenerative conditions. A total of 27 genes identified in this study were previously shown to be changed by alcohol abuse in previous studies of human post-mortem brain. These results revealed a consistent re-programming of gene expression in alcohol abusers that reliably discriminates alcoholic from non-alcoholic individuals.

A need for caution in the use of frontal analysis continuous capillary electrophoresis for the determination of ligand binding data

Attention is drawn to a need for caution in the determination of binding data for protein-polyelectrolyte interactions by frontal analysis continuous capillary electrophoresis (FACCE). Because the method is valid only for systems involving comigration of complex(es) and slower-migrating reactant, establishing conformity with that condition is clearly a prerequisite for its application. However, that requirement has not been tested in any published studies thus far. On the basis of calculated FACCE patterns, presented to illustrate features by which such comigration of complex(es) and slower-migrating reactant can be identified, the form of the published pattern for a P-lactoglobulin-poly(styrenesulfonate) mixture does not seem to signify the migration behavior required to justify its consideration in such terms. Additional experimental studies are therefore needed to ascertain the validity of FACCE as a means of determining binding data for the characterization of protein-polyelectrolyte interactions. (c) 2005 Elsevier Inc. All rights reserved.