Monday Morning Eye Opener, August 10, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, August 24, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, September 14, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, September 21, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, September 28, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, October 5, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, October 12, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, October 19, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, October 26, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, November 2, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, November 9, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Monday Morning Eye Opener, November 16, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Where and how family members spend time at home? A quantitative analysis of the observational tracking on the everyday lives of Italian families

This paper examines a dataset that derives from an observational tracking, in order to analyze where and how middle-class working families spend time at home. We use an ethnographic approach to study the everyday lives of Italian dual-income middle-class families, with the aim to analyze quantitatively the use of home spaces and the types of activities of family members on weekday afternoons and evenings. The different analyses (multiple correspondence analysis, agglomerative hierarchical cluster, discriminant analysis) show how particular spaces and activities in these spaces are dominated by certain family members. We suggest a combination of qualitative and quantitative methodologies as useful tools to explore in detail the everyday lives of families, and to understand how family members use the domestic spaces. In particular, we consider relevant the use of quantitative analyses to examine ethnographic data, especially in connection with the methodological reflexivity among researchers

Monday Morning Eye Opener, November 23, 2015

Weekly Newsletter from the Northwest District Office for libraries containing programs, activities, classes for the upcoming week.

Identification of the minimal promoter region of the mouse NKX5-3, a transcription factor implicated in eye development.

Early ocular development is controlled by a complex network of transcription factors, cell cycle regulators, and diffusible signalling molecules. Together, these molecules regulate cell proliferation and apoptosis, and specify retinal fate. NKX5-3 is a homeobox transcription factor implicated in eye development. The analysis of the 5'-flanking region of the mouse Nkx5-3 gene revealed a predicted TATA-less promoter sequence between -416 and -166 of the translation start site. To functionally characterise Nkx5-3 promoter activity, serial deletions of the promoter sequence were introduced in pGL-3 basic vector and promoter activity of these 5'- and 3'-deleted constructions was tested in HeLa and CHO cells. Transactivation assays identified a region between -350 and -296 exhibiting promoter-like activity. Combined analysis by deletions and point mutations showed that this sequence, containing multiple Sp1 binding sites was necessary to promote transcriptional activity. Binding of Sp1 to this region was confirmed by electrophoretic mobility shift assay (EMSA) and chromatin immunoprecipitation, using an antibody specific for Sp1. Altogether, these results demonstrated that the immediate upstream region of Nkx5-3 gene possessed a strong intrinsic promoter activity in vitro, suggesting a potential role in Nkx5-3 transcription in vivo.