Sonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases

The morphogen Sonic Hedgehog (SHH) plays a critical role in the development of different tissues. In the central nervous system, SHH is well known to contribute to the patterning of the spinal cord and separation of the brain hemispheres. In addition, it has recently been shown that SHH signaling also contributes to the patterning of the telencephalon and establishment of adult neurogenic niches. In this work, we investigated whether SHH signaling influences the behavior of neural progenitors isolated from the dorsal telencephalon, which generate excitatory neurons and macroglial cells in vitro. We observed that SHH increases proliferation of cortical progenitors and generation of astrocytes, whereas blocking SHH signaling with cyclopamine has opposite effects. In both cases, generation of neurons did not seem to be affected. However, cell survival was broadly affected by blockade of SHH signaling. SHH effects were related to three different cell phenomena: mode of cell division, cell cycle length and cell growth. Together, our data in vitro demonstrate that SHH signaling controls cell behaviors that are important for proliferation of cerebral cortex progenitors, as well as differentiation and survival of neurons and astroglial cells.

Annual report of the Division of Apprenticeship.

Report year ends June 30.

STATE OF SOUTH CAROLINA OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW ANNUAL REPORT - 1994-95

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW 1996-1997 ANNUAL REPORT

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

OFFICE OF THE GOVERNOR DIVISION OF FOSTER CARE REVIEW 1998-1999 ANNUAL REPORT

The South Carolina Foster Care Review Board at the Office of Executive Policy and Programs annually publishes a report with summary of programs, recommendations, demographic and statistical information, and directory of state board and staff.

Into the Spotlight: Bringing Transparency, Consistency, and Efficiency to the Division of Appeals and Hearings

Currently, the Division of Appeals and Hearings of the South Carolina Department of Health and Human Services has no specific presence on the agency's website to provide information or to allow for the electronic submission of appeals. This project's focus was developing an online presence for the Division on SCDHHS' website. The page will make the Division's procedures publicly available to beneficiaries, providers, and agency program staff who attend hearings. Additionally, parties will have a secure online portal through which they can file appeals and upload supporting documentation, reducing the need to send appeals via first class mail. The online appeal portal will further the agency' s goal of reducing paper.

Liiketoiminnan jakautumisen verotus

Tutkimuksen päätavoite on ollut selvittää, saavutetaanko liiketoiminnan jakautumisella verotuksessa hyötyä ja missä tilanteissa. Tutkimus on toteutettu toimintoanalyyttisellä tutkimusotteella. Tarkoituksena on ollut analysoida kirjallisuuden ja oikeustapausten avulla liiketoiminnan täydelliseen jakautumiseen liittyviä verotuksellisia kysymyksiä. Empiiristä tietoa on tutkimuksessa mukana puolistrukturoitujen asiantuntijahaastattelujen kautta. Tutkimuksessa havaittiin, että välitöntä verohyötyä jakautuvalle ja vastaanottaville yhtiöille sekä niiden osakkeenomistajille ei jakautumisella voida saavuttaa. Tarkasteltaessa verovaikutuksia pitemmällä ajanjaksolla, jakautumisella osana sarjatoimea voi olla mahdollista saavuttaa verohyötyä. Tapauskohtaisesti on selvitettävä onko kyseessä verosuunnittelu- vai veronkiertotilanne. Esimerkiksi jakautumisessa toteutetulla varallisuuden ja yritystoiminnan erottamisella voidaan saavuttaa verohyötyä osakkeenomistajille. Verohyöty voi toteutua, kun varallisuutta sisältävän yhtiön osakkeista luovutaan. Myöhemmällä osakkeiden myynnillä ei saa olla välitöntä yhteyttä jakautumiseen.

Evaluation of Ohmic Instrument Company model UPM-30 ultrasound power meter /

Mode of access: Internet.

United States of America, petitioner, v. Standard Oil Company of New Jersey et al., defendants.

At head of title: In the Circuit Court of the United States for the Eastern Division of the Eastern Judicial District of Missouri.

Formerly utilized MED/AEC sites remedial action programs : radiological survey of the Hooker Chemical Company, Niagara Falls, N.Y.

Issued Jan. 1977.

Cyclic testing of Rohm and Haas company amberlite anion exchange resins for the recovery of uranium /

"Date Declassified: September 23, 1955."

United States of America, petitioner, v. Standard oil company of New Jersey et al., defendants ...

Vol. 22 and vol. A [v. 23] contain the "Transcript of record" in this case on appeal to the Supreme court of the United States, October term, 1909, no. 725, and are printed by Judd & Detweiler (inc.), printers, Washington, D.C., 1910.

Job instruction; a manual for shop supervisors and instructors; prepared and made available through courtesy of Western electric company.

"References": p. 43.