Rule a wife and have a wife : a comedy

by Beaumont and Fletcher. Adapted for theatrical representation, as performed at the Theatres-Royal Drury-Lane and Covent-Garden. Regulated from the prompt-books, by permission of the managers

The new African slavery; or, King Leopold's rule in Africa

by E. D. Morel

External validation study of a clinical prediction rule for ambulation outcomes after traumatic spinal cord injury

The main objective of this study was to determine the external validity of a clinical prediction rule developed by the European Multicenter Study on Human Spinal Cord Injury (EM-SCI) to predict the ambulation outcomes 12 months after traumatic spinal cord injury. Data from the North American Clinical Trials Network (NACTN) data registry with approximately 500 SCI cases were used for this validity study. The predictive accuracy of the EM-SCI prognostic model was evaluated using calibration and discrimination based on 231 NACTN cases. The area under the receiver-operating-characteristics curve (ROC) curve was 0.927 (95% CI 0.894 – 0.959) for the EM-SCI model when applied to NACTN population. This is lower than the AUC of 0.956 (95% CI 0.936 – 0.976) reported for the EM-SCI population, but suggests that the EM-SCI clinical prediction rule distinguished well between those patients in the NACTN population who were able to achieve independent ambulation and those who did not achieve independent ambulation. The calibration curve suggests that higher the prediction score is, the better the probability of walking with the best prediction for AIS D patients. In conclusion, the EM-SCI clinical prediction rule was determined to be generalizable to the adult NACTN SCI population.^

Nota sobre el Rule of Law y la ética de la virtud

Fil: Massini Correas, Carlos I.. Universidad de Mendoza

Chairmanship in ASEAN+3:A Shared Rule of Behavior

ASEAN+3 is a cooperative framework among ASEAN members and the countries of Japan, China and Korea. It functions at the senior official, ministerial and summit levels. This article concerns how institutions in ASEAN+3 affect development of the direction and nature of this framework. ASEAN+3 is regarded as a loose framework that has regularized meetings as its main activity but has no organizational settings such as the secretariat. Little institutional analysis has been conducted on the development of this framework. This article introduces 'Chairmanship' as an analytical concept in which the chair or chairing member plays an important role in preparing and managing meetings. 'Chairmanship' is therefore an institution with an organizational element. It is also a shared rule of behavior among member states in that the chair's roles are not explicitly written in documents. Thus, it can be argued that the ASEAN+3 framework has an institution with an organizational element that affects development of its characteristics.

Impact of diagonal cumulation rule on FTA utilization : evidence from bilateral and multilateral FTAs between Japan and Thailand

In this paper, we empirically investigate the effect of diagonal cumulation on free trade agreement (FTA) utilization by exploring Thai exports to Japan under two kinds of FTA schemes. While the one scheme adopts bilateral cumulation, the other scheme does diagonal cumulation. Comparing trade under these two kinds of FTAs, we can examine the effect of diagonal cumulation without relying on not only the variation in cumulation rules across country pairs but also the variation across years. In short, our estimates do not suffer from biases from time-variant elements and country pair-specific elements. As a result, our estimates show around 4% trade creation effect of diagonal cumulation, which is much smaller than the estimates in the previous studies (around 15%).

Hybrid Approach Combining Machine Learning and a Rule-Based Expert System for Text Categorization

This paper discusses a novel hybrid approach for text categorization that combines a machine learning algorithm, which provides a base model trained with a labeled corpus, with a rule-based expert system, which is used to improve the results provided by the previous classifier, by filtering false positives and dealing with false negatives. The main advantage is that the system can be easily fine-tuned by adding specific rules for those noisy or conflicting categories that have not been successfully trained. We also describe an implementation based on k-Nearest Neighbor and a simple rule language to express lists of positive, negative and relevant (multiword) terms appearing in the input text. The system is evaluated in several scenarios, including the popular Reuters-21578 news corpus for comparison to other approaches, and categorization using IPTC metadata, EUROVOC thesaurus and others. Results show that this approach achieves a precision that is comparable to top ranked methods, with the added value that it does not require a demanding human expert workload to train

Contribución al estudio de dos conceptos básicos de la lógica fuzzy

La tesis doctoral CONTRIBUCIÓN AL ESTUDIO DE DOS CONCEPTOS BÁSICOS DE LA LÓGICA FUZZY constituye un conjunto de nuevas aportaciones al análisis de dos elementos básicos de la lógica fuzzy: los mecanismos de inferencia y la representación de predicados vagos. La memoria se encuentra dividida en dos partes que corresponden a los dos aspectos señalados. En la Parte I se estudia el concepto básico de «estado lógico borroso». Un estado lógico borroso es un punto fijo de la aplicación generada a partir de la regla de inferencia conocida como modus ponens generalizado. Además, un preorden borroso puede ser representado mediante los preórdenes elementales generados por el conjunto de sus estados lógicos borrosos. El Capítulo 1 está dedicado a caracterizar cuándo dos estados lógicos dan lugar al mismo preorden elemental, obteniéndose también un representante de la clase de todos los estados lógicos que generan el mismo preorden elemental. El Capítulo finaliza con la caracterización del conjunto de estados lógicos borrosos de un preorden elemental. En el Capítulo 2 se obtiene un subconjunto borroso trapezoidal como una clase de una relación de indistinguibilidad. Finalmente, el Capítulo 3 se dedica a estudiar dos tipos de estados lógicos clásicos: los irreducibles y los minimales. En el Capítulo 4, que inicia la Parte II de la memoria, se aborda el problema de obtener la función de compatibilidad de un predicado vago. Se propone un método, basado en el conocimiento del uso del predicado mediante un conjunto de reglas y de ciertos elementos distinguidos, que permite obtener una expresión general de la función de pertenencia generalizada de un subconjunto borroso que realice la función de extensión del predicado borroso. Dicho método permite, en ciertos casos, definir un conjunto de conectivas multivaluadas asociadas al predicado. En el último capítulo se estudia la representación de antónimos y sinónimos en lógica fuzzy a través de auto-morfismos. Se caracterizan los automorfismos sobre el intervalo unidad cuando sobre él se consideran dos operaciones: una t-norma y una t-conorma ambas arquimedianas. The PhD Thesis CONTRIBUCIÓN AL ESTUDIO DE DOS CONCEPTOS BÁSICOS DE LA LÓGICA FUZZY is a contribution to two basic concepts of the Fuzzy Logic. It is divided in two parts, the first is devoted to a mechanism of inference in Fuzzy Logic, and the second to the representation of vague predicates. «Fuzzy Logic State» is the basic concept in Part I. A Fuzzy Logic State is a fixed-point for the mapping giving the Generalized Modus Ponens Rule of inference. Moreover, a fuzzy preordering can be represented by the elementary preorderings generated by its Fuzzy Logic States. Chapter 1 contemplates the identity of elementary preorderings and the selection of representatives for the classes modulo this identity. This chapter finishes with the characterization of the set of Fuzzy Logic States of an elementary preordering. In Chapter 2 a Trapezoidal Fuzzy Set as a class of a relation of Indistinguishability is obtained. Finally, Chapter 3 is devoted to study two types of Classical Logic States: irreducible and minimal. Part II begins with Chapter 4 dealing with the problem of obtaining a Compa¬tibility Function for a vague predicate. When the use of a predicate is known by means of a set of rules and some distinguished elements, a method to obtain the general expression of the Membership Function is presented. This method allows, in some cases, to reach a set of multivalued connectives associated to the predicate. Last Chapter is devoted to the representation of antonyms and synonyms in Fuzzy Logic. When the unit interval [0,1] is endowed with both an archimedean t-norm and a an archi-medean t-conorm, it is showed that the automorphisms' group is just reduced to the identity function.

Analysis of concurrent constraint logic programs with a fixed scheduling rule

The analysis of concurrent constraint programs is a challenge due to the inherently concurrent behaviour of its computational model. However, most implementations of the concurrent paradigm can be viewed as a computation with a fixed scheduling rule which suspends some goals so that their execution is postponed until some condition awakens them. For a certain kind of properties, an analysis defined in these terms is correct. Furthermore, it is much more tractable, and in addition can make use of existing analysis technology for the underlying fixed computation rule. We show how this can be done when the starting point is a framework for the analysis of sequential programs. The resulting analysis, which incorporates suspensions, is adequate for concurrent models where concurrency is localized, e.g. the Andorra model. We refine the analysis for this particular case. Another model in which concurrency is preferably encapsulated, and thus suspensions are local to parts of the computation, is that of CIAO. Nonetheless, the analysis scheme can be generalized to models with global concurrency. We also sketch how this could be done, and we show how the resulting analysis framework could be used for analyzing typical properties, such as suspensión freeness.

Artificial pancreas using a personalized rule-based controller achieves overnight normoglycemia in patients with type 1 diabetes

Objective: This study assessed the efficacy of a closed-loop (CL) system consisting of a predictive rule-based algorithm (pRBA) on achieving nocturnal and postprandial normoglycemia in patients with type 1 diabetes mellitus (T1DM). The algorithm is personalized for each patient’s data using two different strategies to control nocturnal and postprandial periods. Research Design and Methods: We performed a randomized crossover clinical study in which 10 T1DM patients treated with continuous subcutaneous insulin infusion (CSII) spent two nonconsecutive nights in the research facility: one with their usual CSII pattern (open-loop [OL]) and one controlled by the pRBA (CL). The CL period lasted from 10 p.m. to 10 a.m., including overnight control, and control of breakfast. Venous samples for blood glucose (BG) measurement were collected every 20 min. Results: Time spent in normoglycemia (BG, 3.9–8.0 mmol/L) during the nocturnal period (12 a.m.–8 a.m.), expressed as median (interquartile range), increased from 66.6% (8.3–75%) with OL to 95.8% (73–100%) using the CL algorithm (P<0.05). Median time in hypoglycemia (BG, <3.9 mmol/L) was reduced from 4.2% (0–21%) in the OL night to 0.0% (0.0–0.0%) in the CL night (P<0.05). Nine hypoglycemic events (<3.9 mmol/L) were recorded with OL compared with one using CL. The postprandial glycemic excursion was not lower when the CL system was used in comparison with conventional preprandial bolus: time in target (3.9–10.0 mmol/L) 58.3% (29.1–87.5%) versus 50.0% (50–100%). Conclusions: A highly precise personalized pRBA obtains nocturnal normoglycemia, without significant hypoglycemia, in T1DM patients. There appears to be no clear benefit of CL over prandial bolus on the postprandial glycemia

A new similarity function for generalized trapezoidal fuzzy numbers

Numerous authors have proposed functions to quantify the degree of similarity between two fuzzy numbers using various descriptive parameters, such as the geometric distance, the distance between the centers of gravity or the perimeter. However, these similarity functions have drawback for specific situations. We propose a new similarity measure for generalized trapezoidal fuzzy numbers aimed at overcoming such drawbacks. This new measure accounts for the distance between the centers of gravity and the geometric distance but also incorporates a new term based on the shared area between the fuzzy numbers. The proposed measure is compared against other measures in the literature.

Rule Representation in Distributed Environments with Accepting Networks of Splicing Processors.

This paper presents the model named Accepting Networks of Evolutionary Processors as NP-problem solver inspired in the biological DNA operations. A processor has a rules set, splicing rules in this model,an object multiset and a filters set. Rules can be applied in parallel since there exists a large number of copies of objects in the multiset. Processors can form a graph in order to solve a given problem. This paper shows the network configuration in order to solve the SAT problem using linear resources and time. A rule representation arquitecture in distributed environments can be easily implemented using these networks of processors, such as decision support systems, as shown in the paper.

Personalized rule-based closed-loop control algorithm for type 1 diabetes

Type 1 diabetes-mellitus implies a life-threatening absolute insulin deficiency. Artificial pancreas (CGM sensor, insulin pump and control algorithm) is promising to outperform current open-loop therapies.

Searching for a consensus similarity function for generalized trapezoidal fuzzy numbers

There is controversy regarding the use of the similarity functions proposed in the literature to compare generalized trapezoidal fuzzy numbers since conflicting similarity values are sometimes output for the same pair of fuzzy numbers. In this paper we propose a similarity function aimed at establishing a consensus. It accounts for the different approaches of all the similarity functions. It also has better properties and can easily incorporate new parameters for future improvements. The analysis is carried out on the basis of a large and representative set of pairs of trapezoidal fuzzy numbers.