Globalização, Estado e crise estrutural do capital

Pós-graduação em Economia - FCLAR

Physa mezzalirai: um novo gastrópode da formação Adamantina (Bacia Bauru), Cretáceo Superior, São Paulo, Brasil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Geração Y: característica de um novo ouvinte

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Planos diretores participativos e gestão urbana em cidades médias sob o estatuto da cidade

The paper analyzes the implementation of the new regulatory framework of urban policy in Brazil, synthesized by the Constitution of 1988 and its subsequent regulations by the Statute of the City (Federal Law No. 10.257/2001). The empirical analysis focuses on three medium-sized cities in the state of São Paulo (Piracicaba, Bauru and Rio Claro), and addresses three complementary dimensions. First: interprets the participatory processes that resulted in the new Master Plan. Second, analyzes the crisis of the developmental model for understanding the transformations experienced by the Brazilian urban network, through which the medium-sized cities took on increasing economic relevance. Third: examines the inclusion and regulation of Special Zones of Social Interest (ZEIS) and how this instrument has been used in dealing with urban problems and the housing deficit. Apart from normative considerations, the study aims to assess the actual contribution of the City Statute in the democratization of urban management.

O clima urbano das cidades do interior do estado de São Paulo: uma análise do campo térmico de Assis, Cândido Mota, Maracaí e Tarumã

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ética, justiça e democracia em sala de aula: o desenvolvimento e a experiência de um novo método de discussão de dilemas morais para a educação

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Saberes docentes, sistema de avaliação de rendimento escolar do Estado de São Paulo e ensino de Ciências: um estudo de caso a partir de situações de ensino-aprendizagem

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Indústria frigorífica halal no Brasil, mão-de-obra islamita e estado de exceção

In the last decade, Brazilian meat export rates for Muslim religious countries have increased, and also has the immigration of Africans workers able to perform the slaughter following the precepts of Islam - religion that has expanded in the world, and thus, has the halal food segment. Halal, the Islamic ideology, means lawful, authorized by God: are those products that Allah in the Holy Qur'an releases for human consumption. To get halal certification some measures during slaughter/processing food should be taken. In the case of the slaughterhouses the animal must be slaughtered by a Muslim. Consequently, the demand for this skilled labor makes many African-Muslims get jobs in factories owned by BRF Foods, JBS and Marfrig; refugees and with their citizenship rights committed, these individuals live in a socio-political state of exception and overexploitation. In this study we intend to discuss the object of study Islamist workforce in Brazilian halal meat industry using the theoretical reflections of Giorgio Agamben (Homo Sacer in 2002, and State of Exception, 2004) and David Harvey (The Condition of Postmodernity, 2008, and The New Imperialism, 2004) to address the situation of immigrants in the meat business in Brazil, specially those on the halal certification segment, whose working and living conditions were described from academic studies and primary sources (articles in newspapers / magazines, websites, immigration official data). In addition we use the works of Rogério Heasbaert (O mito da desterritorialização, 2007) and Robert Kurz (Os paradoxos dos direitos humanos: inclusão e exclusão na modernidade, 2003) to discuss human mobility in this new century

Carimbó do Santo Preto: a presença negra na performance musical da festividade do Glorioso São Benedito em Santarém Novo (PA)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Carimbó do Santo Preto: a presença negra na performance musical da festividade do Glorioso São Benedito em Santarém Novo (PA)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The antioxidative effect of de novo generated vitamin B-6 in Plasmodium falciparum validated by protein interference

The malaria parasite Plasmodium falciparum is able to synthesize de novo PLP (pyridoxal 5'-phosphate), the active form of vitamin B-6. In the present study, we have shown that the de novo synthesized PLP is used by the parasite to detoxify O-1(2) (singlet molecular oxygen), a highly destructive reactive oxygen species arising from haemoglobin digestion. The formation of O-1(2) and the response of the parasite were monitored by live-cell fluorescence microscopy, by transcription analysis and by determination of PLP levels in the parasite. Pull-down experiments of transgenic parasites overexpressing the vitamin B-6-biosynthetic enzymes PfPdx1 and PfPdx2 clearly demonstrated an interaction of the two proteins in vivo which results in an elevated PLP level from 12.5 mu M in wild-type parasites to 36.6 mu M in the PfPdx1/PfPdx2-overexpressing cells and thus to a higher tolerance towards O-1(2). In contrast, by applying the dominant-negative effect on the cellular level using inactive mutants of PfPdx1 and PfPdx2, P. falciparum becomes susceptible to O-1(2). Our results demonstrate clearly the crucial role of vitamin B-6 biosynthesis in the detoxification of O-1(2) in P falciparum. Besides the known role of PLP as a cofactor of many essential enzymes, this second important task of the vitamin B-6 de novo synthesis as antioxidant emphasizes the high potential of this pathway as a target of new anti-malarial drugs.

The clinical impact of chromosomal rearrangements with breakpoints upstream of the SOX9 gene: two novel de novo balanced translocations associated with acampomelic campomelic dysplasia

Abstract Background The association of balanced rearrangements with breakpoints near SOX9 [SRY (sex determining region Y)-box 9] with skeletal abnormalities has been ascribed to the presumptive altering of SOX9 expression by the direct disruption of regulatory elements, their separation from SOX9 or the effect of juxtaposed sequences. Case presentation We report on two sporadic apparently balanced translocations, t(7;17)(p13;q24) and t(17;20)(q24.3;q11.2), whose carriers have skeletal abnormalities that led to the diagnosis of acampomelic campomelic dysplasia (ACD; MIM 114290). No pathogenic chromosomal imbalances were detected by a-CGH. The chromosome 17 breakpoints were mapped, respectively, 917–855 kb and 601–585 kb upstream of the SOX9 gene. A distal cluster of balanced rearrangements breakpoints on chromosome 17 associated with SOX9-related skeletal disorders has been mapped to a segment 932–789 kb upstream of SOX9. In this cluster, the breakpoint of the herein described t(17;20) is the most telomeric to SOX9, thus allowing the redefining of the telomeric boundary of the distal breakpoint cluster region related to skeletal disorders to 601–585 kb upstream of SOX9. Although both patients have skeletal abnormalities, the t(7;17) carrier presents with relatively mild clinical features, whereas the t(17;20) was detected in a boy with severe broncheomalacia, depending on mechanical ventilation. Balanced and unbalanced rearrangements associated with disorders of sex determination led to the mapping of a regulatory region of SOX9 function on testicular differentiation to a 517–595 kb interval upstream of SOX9, in addition to TESCO (Testis-specific enhancer of SOX9 core). As the carrier of t(17;20) has an XY sex-chromosome constitution and normal male development for his age, the segment of chromosome 17 distal to the translocation breakpoint should contain the regulatory elements for normal testis development. Conclusions These two novel translocations illustrate the clinical variability in carriers of balanced translocations with breakpoints near SOX9. The translocation t(17;20) breakpoint provides further evidence for an additional testis-specific SOX9 enhancer 517 to 595 kb upstream of the SOX9 gene.

Estado, globalização e políticas educacionais : Mídia na Educação

O presente artigo tem como objetivo, verificar como as mídias na educaçao sao usadas pelo Estado. O Brasil, sendo um país em desenvolvimento, na aérea da educaçao passa por várias transformaçoes. Discussoes que partem desde o percentual do Produto Interno Bruto (PIB) para a educaçao até a discussao sobre a federalizaçao da educaçao. Com a globalizaçao, as políticas educacionais existentes, graças à modernidade técnica/tecnológica, passam por modificaçao. Porém, a globalizaçao pode deixar uma parcela da populaçao sem acesso a essas novas políticas educacionais, pois já que precisam de um novo suporte, alguns podem ser excluídos, mas se torna tarefa governamental levar essa nova forma de educaçao para todos, sem exclusao. Devemos buscar ampliar cada vez mais o acesso de todos à informaçao e as novas tecnologias, por uma política educacional democrática e aberta para todos os brasileiros, na forma da lei. Isso deve ser feito com seriedade, sem monopolizar informaçoes, e sociologicamente dizendo direitos e deveres de todos para com a formaçao de uma sociedade mais igualitária e justa. Assim, observamos um novo cenário, onde a globalizaçao avança, a tecnologia acompanha este crescimento, que deve ser acompanhado pelas políticas educacionais do Estado

Migrações para assentamentos rurais : Analisando as trajetórias de assentados no município de Padre Bernardo no Estado de Goiás Brasil

This work is the result of a case study that analyzes the trajectories of migrants to rural settlements located in the municipality of Padre Bernardo, the region surrounding the Federal District, Goiás State in this region several settlements created in the late 90's, were consisting of workers of rural origin who migrated from various regions of Brazil to work, especially in services and construction in Brasilia before reaching settlements. Thus, the text aims to give some reflections on understanding the dynamics of migration to rural settlements in Brazil trajectories with rural-city-settlements. As consideration, it was noticed that after many years or even decades living in the city, these migrants decide to join the struggle for land and depart for land occupation in the region. In the settlement, the settlers are facing a new challenge that will be built collectively and individually

Migrações para assentamentos rurais : Analisando as trajetórias de assentados no município de Padre Bernardo no Estado de Goiás Brasil

This work is the result of a case study that analyzes the trajectories of migrants to rural settlements located in the municipality of Padre Bernardo, the region surrounding the Federal District, Goiás State in this region several settlements created in the late 90's, were consisting of workers of rural origin who migrated from various regions of Brazil to work, especially in services and construction in Brasilia before reaching settlements. Thus, the text aims to give some reflections on understanding the dynamics of migration to rural settlements in Brazil trajectories with rural-city-settlements. As consideration, it was noticed that after many years or even decades living in the city, these migrants decide to join the struggle for land and depart for land occupation in the region. In the settlement, the settlers are facing a new challenge that will be built collectively and individually