Queratoses actínias disseminadas de membros superiores: comparação da terapia fotodinâmica com ácido aminolevulínico 15%¨e metil aminolevulínico 15 % através do protótico kerato PDT

Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) - FMB

Associação fitoterápica no tratamento de feridas cutâneas induzidas em equinos

The efficiency of the topical use of a commercial product constituted by a herbal combination on the healing evolution of equine induced wounds was studied. A skin lesion in the shape of a square with 5cm sides was surgically produced on both sides of the buttocks of eight adult horses. One side was considered control and another one treated. Both control and treated sides were rinsed with water and neutral soap. Additionally, the wound on the treated side received the topical treatment with the herbal combination. Macroscopic and microscopic healing evolution of the wounds was evaluated and their areas were determined during the experimental period. There was statistical difference between wound areas. At the last evaluation, the average area of the control side was 0.70cm² and of the treated side was 1.23cm². The contraction of scar observed at 77 days was 97.57% for the control side and 95.59% for the treated side.

Caracterização de lesões desportivas no basquetebol

INTRODUCTION: Basketball is characterized with high injury rate. In the literature it's not defined whether or not there are differences between the sexes. OBJECTIVE: Characterize and analyze the incidence of athletic injuries in basketball players, comparing the sexes. MATERIALS AND METHODS: Fifteen under-23 category athletes of each sex were interviewed with the reported morbidity inquire. RESULTS: The age of the female and male teams, in average, was 18 ± 0.65 and 18.20 ± 1.57 years respectively. The male team had more injuries than the female one (respectively 2.6 ± 1.45 against 1.2 ± 1.18, p < 0.05). The joint damage was the most common injury in the male team, representing 58.97%, and the second most common in the female team (33.33%). The lower limbs were the most common injured sites (80.95% in the female and 69.23% in the male). The most frequent injury mechanism in the male team was the landing (43.59%), and in the female was the vertical jump (28.57%). In both teams the most injuries occurred during the training (61.9% in the female and 71.8% in the male). The absence was necessary in 47.62% (female) and 56.41% (male). Great part of the athletes didn't received any treatment (61.9% and 51.28% in the female and male team respectively). The return to the activities was mostly symptomatic, in both female and male team (85.71% and 84.62% respectively). CONCLUSION: The incidence of injuries in basketball is higher in the lower limbs. The male team is more likely to suffer injuries, and the main injury mechanisms were different between male and female team.

Características das lesões desportivas e fatores associados com lesão em iniciantes de ginástica artística do sexo feminino

The artistic gymnastics is a modality that associates arts with biomechanical gestures, and it has been prominent among children and adolescents. Its practice can lead to sports injuries; therefore, it is important to know the factors inherent to trauma for the formulation of preventive models. Thus, the objective of this study was to characterize sports injuries and to verify factors associated with injury in people practicing artistic gymnastics with different levels of competitiveness. Forty-six gymnasts were interviewed with mean age of 10.1±2.0 years for female participants, who were classified in two competitive levels, i.e, initiation and training. We used the morbidity questionnaire adapted to sports characteristics to collect personal, training, and injury data. It was observed that injury risk was 0.3 injuries per athlete and 1.4 injuries per injured athlete, in which the gymnasts of the training category showed a higher frequency of the injury (83.3%; n=10) compared with the ones in the initiation category (10.5%; n=4). For both levels of competitiveness, training moment and light severity were the most reported variables. In the mechanism, contactless was more prevalent in the training category (90%; n=9) and the direct contact was more common at initiation category (75%; n=3). Anthropometric and training variables were considered as factors associated with injury to the gymnasts. It is concluded that gymnasts of the training category have higher injury frequency. Anthropometric and training variables were factors associated with injury. Characteristics of the injuries depend on the competitiveness level of the ­gymnasts.

Efeito da suplementação de vitamina D no desenvolvimento de lesões pré-neoplásicas quimicamente induzidas em ratos Wistar macho

Pós-graduação em Biologia Geral e Aplicada - IBB

Plasma rico em plaquetas empregado na cirurgia reconstrutiva em coelhos (Oryctolagus cuniculus): avaliação da exequibilidade da técnica, achados macroscópicos e histopatológicos

Pós-graduação em Cirurgia Veterinária - FCAV

Estudo clínico comparativo entre sutura convencional e vaporização a laser de dióxido de carbono (CO2) em pele de ratos

The proposal of this study was to compare a wound healing between conventional suture and vaporization with CO2 laser in rats skin. ln such case 24 rats were utilized, making two longitudinal incisions in dorsum by scalpel. ln the left side incision the wound was sutured with nylon thread. ln the right side incision the wound were close by approach and vaporized with C02 laser, defocusing, 8 watts in continuous mode. The wound healing was followed by clinical photographic taking at the times: immediately after the procedure, 24 hours, 3, 7, 14, and 21 days. The results showed an early delay of reparation in healing vaporized in comparison with the sutured one, however occurred 21 days both repair tissue showed the same clinical characteristic. This results suggested that the C02 laser can be used by eventual substitute of suture.

Atividade antimicrobiana da carbodiimida (EDC) sobre microorganismos presentes em lesões cariosas

Pós-graduação em Ciências Odontológicas - FOAR

Comportamento térmico de coberturas em camadas duplas e estudo da substituição da cama por piso plástico na qualidade do ar, desempenho e índice de lesões em frangos de corte

Pós-graduação em Zootecnia - FCAV

Avaliação do efeito da lectina Artin M na expressão de fatores de crescimento e citocinas inflamatórias relacionadas ao processo de repação tecidual: Estudo in vitro em macrófagos e fibroblastos gengivais de ratos

Pós-graduação em Odontologia - FOAR

Incidência e Caracterização de Lesões Desportivas no Taekwondo segundo o Gênero

Taekwondo practice has been associated with physical and biomechanical overloads, which are related to occurrence of sports injuries (SI). However, etiological and nosographic information about SI are limited and conflicting. This study analyzed and characterized the SI in Taekwondo athletes, according to gender. Casuistic integrated 22 athletes, 12 men and 10 women, athletes from São Paulo State Team of Taekwondo, adult category, with 23,6±6,8 years, body weight of 66,0±13,1 kg and 1,72±0,09 m of height. Reported morbidity survey was used to obtain retroactive information to 2009 season. Nosographic variables were analyzed using Goodman’s Test for contrasts among multinomial populations. All athletes reported injuries in the season; 56 cases were registered, determining an injury rate of 2.54 SI/athlete; 26 events (46.4%) occurred in males (2.17 SI/athlete), and 30 (53.6%) were related to women (3.00 SI/athlete). There were predominance of injuries in joints (35,7%) and muscles (39,3%); both genders presented injuries in lower members (82.1%, p<0.01), predominant in combat situations (80.4%, p<0.05), during the preparatory period of training (73.2%). There was a higher treatment request among male athletes (73.1%), which showed high asymptomatic return (69.2%); the female group referred similar proportions of absence and presence of treatment request, collaborating for the greater symptomatic return of these athletes (70.0%). In conclusion, the results support predominance of muscles and joints injuries in lower segments, derived from fighting, involving female athletes.

Caracterização das lesões desportivas em atletas de Tênis de Mesa

Introduction: The table tennis is characterized by requiring of the athletes intense body movement. The gestures performed by athletes require continuous postural changes, in cases of any sway in body structures may produce postural changes or initiate processes of injuries. Objective: The aim of this study was to characterize the table tennis lesions. Method: Were evaluated 31 athletes (26 males and fi ve females) with mean age 22.35±6.67 years. The subjects were interviewed with the Reported Morbidity Inquires retroactive to the 2009 season. It was used techniques of descriptive and analytical statistics. Results: The largest number of injuries was muscular (74.35%), on the shoulder (43.58%) during the movement of top spin (33.33%) in the specifi c training phase (64.1%) with symptomatic return to the activities (69.23%). Conclusion: The weekly training workload infl uences the number of lesions.

Avaliação da expressão gênica e de lesões no DNA de índividuos portadores de diabetes mellitus tipo 2, dislipidemia e periodontite crônica

Pós-graduação em Odontologia - FOAR

Estudo da associação de polimorfismos no gene MC1R com cor de pele e cor de cabelo para fins forenses

Melanin is a very important pigment to human species, and besides defining skin, eyes and hair color, it is also involved in sun exposure protection. This pigment is classified into two subtypes: pheomelanin, which is responsible for lighter pigmentation and eumelanin, the dark pigment related. Due to this type of melanin variation it is possible to found different phenotypes of hair and skin color. The genetics MC1R variations are described as the most important for diversity in pigmentation, and this gene is directly related to the complex process of melanin synthesis. The use of these variations to phenotype prediction using genetic information has been used in Europe countries to infer physical features from biological samples, with the purpose of directing searches of criminal suspects and victims identification. The aim of this study was to analyze 8 major MC1R polymorphisms in a sample of Brazilian individuals. Analyzing 91 individuals, we observed with higher frequencies the polymorphisms rs1805005:G>T, rs2228479:G>A and rs885479:G>A, which are related to skin and hair colors, as previously showed in literature. These data suggest the possibility of predicting phenotype from genetic polymorphisms in Brazilian population. However it will be necessary to analyze a larger number of individuals to be able to confirm these associations and to perform a more detailed statistical analysis

Estudo da toxicidade de diferentes doses do Diuron (3-(3,4 -dichlorophenyl)-1,1-dimethylurea) no epitélio da bexiga de ratos wistas machos por microscopia eletrônica de varredura

Diuron (3-(3,4-Dichlorophenyl)-1,1-dimethylurea) is a substituted urea herbicide widely used on agricultural crops such as soy, cotton and sugar cane. In a previous long-term study this herbicide exerted carcinogenic activity on the urinary bladder and renal pelvis mucosa of Wistar rats and breast of mice. Also, it was shown to be carcinogenic to the mice skin in a initiation-promotion assay. In 1997, the northamerican EPA evaluated Diuron as a “known/likely” carcinogen for humans (USEPA, 2004). In a previous study developed at this laboratory, male Wistar rats treated with Diuron 2500 ppm during 20 weeks presented increased indices of cell proliferation and incidences of simple urothelial hyperplasia (HS) in the urinary bladder. Under scanning electron microscopy (SEM) severe urothelial necrosis and hyperplasia were observed. However, in that study the urinary bladders of animals exposed to lower doses of Diuron were not examined under SEM. Therefore, the possible dose-response influence of Diuron on the urothelium under SEM is not known. The present study aimed to analyze under SEM the urinary bladder of male Wistar rats exposed to 125 ppm, 500 ppm and 2500 ppm doses of Diuron through diet during 20 weeks and to compare to the previous histological findings in the same material. Under SEM, 125 ppm and 2500 ppm groups presented significantly (p<0,05) increased incidences of simple hyperplasia, i.e., 7/10 and 8/10 respectively, compared to control group and the 500 ppm group The sensitivity of SEM was higher since it detected a 45% incidence of hyperplasiaswhile the histological analysis found only 27%. Considering SEM as the gold-standard, histology showed a 44% sensitivity, 86.4% specificity, a positive predictive value of 72,7% and negative predictive value of 65,5% and accuracy of 67,5%. Scanning Electron Microscopy...(Complete abstract click electronic access below)