José Feliciano de Castilho e a tradição clássica no séc. XIX: os adágios de Publílio Siro

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Recepção de Odorico Mendes: (a)casos de crítica de tradução no séc. XIX

This paper aims at gathering evidences about the reception of Odorico Mendes Greek andRoman translations among his contemporaries. Some of the most celebrated lusophone writersof the 19th Century such as Joaquim Manoel de Macedo, Gonçalves Dias and AntónioFeliciano de Castilho left us their reviews on the work of Mendes, the most productiveand controversial Brazilian translator of the time. The analysis of those data provides valuabledocuments of translation criticism that could constitute evidence of translation practices andmethods in an historical period in which Ancient Literature poetic translations were mostlyproduced.

Oneirokritika de Artemidouro de Daldis (séc. II D. C.): livros de análise de sonhos - livro V

Pós-graduação em Linguística e Língua Portuguesa - FCLAR

Regeneração natural do componente arbóreo após a mortalidade de um maciço de taquara em um fragmento de floresta ombrófila mista em Lages - SC

The present study aimed to analyze the floristic and structural descriptors of tree species natural regeneration in a forest sector with synchronized bamboo (Merostachys multiramea Hackel) die-off (CT) and an adjacent area with continuous canopy cover (ST) in an araucaria forest fragment in the municipality of Lages, Santa Catarina state. A total of 14, 5x5m, plots (six plots in CT sector and eight in ST sector) were allocated, where all tree species regenerative individual with circumference at breast height smaller than 15cm and height higher than 25cm was measured (diameter at soil level) and identified. The richest families were: Myrtaceae (nine), Solanaceae (six) and Aquifoliaceae (four). The Shannon Diversity Index in ST and CT sectors were respectively 2.73 and 2.31. The species with the highest importance values in CT sector were Solanum variabile, Piptocarpha angustifolia, Mimosa scabrella, Jacaranda puberula and Solanum pseudoquina. In ST sector, the species with highest importance values were Myrsine lorentziana, Casearia decandra, Cinnamodendron dinisii, Drimys brasiliensis and Ilex paraguariensis. The results showed that the synchronized bamboo die-off influenced the spatial variation in the floristic and structural descriptors of the tree species natural regeneration.

O campo térmico e a qualidade ambiental urbana em Chapecó/SC

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Previsão da capacidade de carga de estacas escavadas em solo arenoso da região de Araquari-SC

In Geotechnical engineering the foundation projects depend on the bearing capacity and the acceptable displacements. One of the possible ways to predict the bearing capacity of foundations is through semi-empirical statistical methods which correlate in-situ tests (SPT and CPT). The piles breaking loads are defined by the interpretation of the load x head displacement curve and the experimental data acquired through the load test. In this work it is studied the behavior of bored piles executed in the Araquari/SC region, comparing the bearing capacity values predicted by the methods DECOURT & QUARESMA MODIFICADO (1996), AOKI & VELLOSO MODIFICADO MONTEIRO (2000), MILITITISKY E ALVES (1985), DECOURT & QUARESMA (1978), MÉTODO DE AOKI & VELLOSO (1975) e PHILOPANNAT (1986), with the results of the load test, evaluating their differences and discussing parameters that have direct effects on the prediction

Six Mile Creek Presbyterian Church, Lancaster County, SC Records - Accession 194 - M86 (110)

The Six Mile Presbyterian Church, Lancaster County, SC Records consist of photocopies of a Six Mile Creek Presbyterian Church ledger, containing minutes of church meetings, registers of pastors, elders and deacons, minutes of the church session, registers of communicants, baptisms and deaths. Six Mile Presbyterian Church was started organized sometime around 1804. Included is a note stating the original ledger was rebound in 1971.

Bethel Baptist Church of Sumter, SC, History - Accession 209 - M93 (119)

The Bethel Baptist Church of Sumter, SC History consists of a short history of Bethel Baptist Church in Sumter, SC from its beginning in 1780 to 1974.

Previsão da capacidade de carga de estacas escavadas em solo arenoso da região de Araquari-SC

In Geotechnical engineering the foundation projects depend on the bearing capacity and the acceptable displacements. One of the possible ways to predict the bearing capacity of foundations is through semi-empirical statistical methods which correlate in-situ tests (SPT and CPT). The piles breaking loads are defined by the interpretation of the load x head displacement curve and the experimental data acquired through the load test. In this work it is studied the behavior of bored piles executed in the Araquari/SC region, comparing the bearing capacity values predicted by the methods DECOURT & QUARESMA MODIFICADO (1996), AOKI & VELLOSO MODIFICADO MONTEIRO (2000), MILITITISKY E ALVES (1985), DECOURT & QUARESMA (1978), MÉTODO DE AOKI & VELLOSO (1975) e PHILOPANNAT (1986), with the results of the load test, evaluating their differences and discussing parameters that have direct effects on the prediction

Prevalence and risk factors of Hepatitis C virus infection in Brazil, 2005 through 2009: a cross-sectional study

Abstract Background Hepatitis C chronic liver disease is a major cause of liver transplant in developed countries. This article reports the first nationwide population-based survey conducted to estimate the seroprevalence of HCV antibodies and associated risk factors in the urban population of Brazil. Methods The cross sectional study was conducted in all Brazilian macro-regions from 2005 to 2009, as a stratified multistage cluster sample of 19,503 inhabitants aged between 10 and 69 years, representing individuals living in all 26 State capitals and the Federal District. Hepatitis C antibodies were detected by a third-generation enzyme immunoassay. Seropositive individuals were retested by Polymerase Chain Reaction and genotyped. Adjusted prevalence was estimated by macro-regions. Potential risk factors associated with HCV infection were assessed by calculating the crude and adjusted odds ratios, 95% confidence intervals (95% CI) and p values. Population attributable risk was estimated for multiple factors using a case–control approach. Results The overall weighted prevalence of hepatitis C antibodies was 1.38% (95% CI: 1.12%–1.64%). Prevalence of infection increased in older groups but was similar for both sexes. The multivariate model showed the following to be predictors of HCV infection: age, injected drug use (OR = 6.65), sniffed drug use (OR = 2.59), hospitalization (OR = 1.90), groups socially deprived by the lack of sewage disposal (OR = 2.53), and injection with glass syringe (OR = 1.52, with a borderline p value). The genotypes 1 (subtypes 1a, 1b), 2b and 3a were identified. The estimated population attributable risk for the ensemble of risk factors was 40%. Approximately 1.3 million individuals would be expected to be anti-HCV-positive in the country. Conclusions The large estimated absolute numbers of infected individuals reveals the burden of the disease in the near future, giving rise to costs for the health care system and society at large. The known risk factors explain less than 50% of the infected cases, limiting the prevention strategies. Our findings regarding risk behaviors associated with HCV infection showed that there is still room for improving strategies for reducing transmission among drug users and nosocomial infection, as well as a need for specific prevention and control strategies targeting individuals living in poverty.

Inclusão digital e capacidade funcional de idosos residentes em Florianópolis, Santa Catarina, Brasil (EpiFloripa 2009-2010)

OBJETIVO: Estudar a relação entre inclusão digital, na forma de troca de mensagens pela Internet, e capacidade funcional de idosos residentes em Florianópolis, Santa Catarina, Brasil. MÉTODOS: Utilizaram-se dados do EpiFloripa Idoso, um estudo transversal de base populacional com idosos (60+ anos) realizado entre 2009 e 2010. A capacidade funcional foi representada pela dificuldade ou incapacidade na realização de atividades básicas ou instrumentais da vida diária, e constituiu a variável dependente denominada dependência funcional. A variável independente principal foi a capacidade autorreferida de enviar e receber mensagens pela Internet usando um computador. Razões de prevalência (PR) e intervalos de confiança de 95% (IC95%) foram estimados em modelo multivariável por regressão de Poisson. RESULTADOS: A amostra compreendeu 1.656 idosos entre 60 e 102 anos com idade média de 70,39 anos (DP = 7,79). Os idosos que conseguiam enviar e receber mensagens pela Internet sem dificuldade apresentaram prevalência significativamente menor de dependência funcional moderada/grave (RP = 0,61; IC95%: 0,40 - 0,94) após ajuste para fatores demográficos, socioeconômicos, de saúde e comportamentais. CONCLUSÕES: A troca de mensagens pela Internet possui forte associação com independência funcional. Não é possível inferir a relação de causalidade dessa associação. Estudos alicerçam a hipótese de que a troca de mensagens pela Internet e a independência funcional tenham uma associação bidirecional, aditiva e sinérgica. Estudos longitudinais poderiam investigar os mecanismos envolvidos nessa associação, para fundamentar políticas de inclusão digital de idosos e para identificar qual o perfil de idosos que mais se beneficiaria com essa inclusão.

Valutazione dell'efficacia dell'infusione intraepatica di cellule staminali (SC) autologhe CD133+ in pazienti affetti da cirrosi ed insufficienza epatica di grado avanzato

Numerose evidenze sperimentali hanno dimostrato il contributo delle cellule staminali (SC) di derivazione midollare nei processi di rigenerazione epatica dopo danno tissutale. E’ cresciuto pertanto l’interesse sul loro potenziale impiego in pazienti con cirrosi. Questo studio si proponeva di valutare la fattibilità e la sicurezza della reinfusione intraepatica di cellule staminali midollari autologhe CD133+ in 12 pazienti con insufficienza epatica terminale. Previa mobilizzazione nel sangue periferico mediante somministrazione di granulocyte-colony stimulating factor (G-CSF) alla dose di 7,5 mcg/Kg/b.i.d. e raccolta per leucoaferesi (solo se la concentrazione di CD133 + SC era > 8/μL), le cellule CD133+ altamente purificate sono state reinfuse in arteria epatica a partire da 5x104/Kg fino a 1x106/kg. Nei tre giorni successivi è stato somministrato G-CSF per favorire l’espansione e l’attecchimento delle cellule. Durante la fase della mobilizzazione e quella della reinfusione sono stati eseguiti saggi biologici quali: caratterizzazione fenotipica delle SC circolanti, saggi clonogenici, valutazione della concentrazione sierica del Hepatocyte Growth Factor (HGF), Stromal-Derived Factor-1 (SDF-1) ed il Vascular-Endotelial Growth Factor (VEGF) e caratterizzazione fenotipica delle CD133+SC purificate. Fino ad oggi sono stati reinfusi 12 pazienti. Questi dati preliminari suggeriscono che è possibile mobilizzare e reinfondere un numero considerevole di SC autologhe CD133+ altamente purificate in pazienti con ESLD . Gli studi biologici mostrano che: il numero di progenitori ematopoietici ed endoteliali circolanti è aumentato dopo il trattamento con G–CSF; le SCs CD133+ altamente purificato esprimono marcatori emopoietici ed endoteliali; la concentrazione sierica di HGF, SDF-1, VEGF e la capacità clonogenica di progenitori emopoietici sono aumentati durante la mobilitazione e nelle fasi di reinfusione; il potenziale clonogenico dei progenitori endoteliali mostra espressione variabile.

Development and evaluation of a 44 Ti, 44 Sc radionuclide generator and labeling of biomolecules with 44 Sc and 68 Ga for PET imaging

Non-invasive molecular-imaging technologies are playing a key role in drug discovery, development and delivery. Positron Emission Tomography (PET) is such a molecular imaging technology and a powerful tool for the observation of various deceases in vivo. However, it is limited by the availability of vectors with high selectivity to the target and radionuclides with a physical half-life which matches the biological half-life of the observed process. The 68Ge/68Ga radionuclide generator makes the PET-nuclide anywhere available without an on-site cyclotron. Besides the perfect availability 68Ga shows well suited nuclide properties for PET, but it has to be co-ordinated by a chelator to introduce it in a radiopharmaceuticals.rnHowever, the physical half-life of 68Ga (67.7 min) might limit the spectrum of clinical applications of 68Ga-labelled radiodiagnostics. Furthermore, 68Ga-labelled analogues of endoradiotherapeuticals of longer biological half-live such as 90Y- or 177Lu-labeled peptides and proteins cannot be used to determine individual radiation dosimetry directly. rnThus, radionuclide generator systems providing positron emitting daughters of extended physical half-life are of renewed interest. In this context, generator-derived positron emitters with longer physical half-life are needed, such as 72As (T½ = 26 h) from the 72Se/72As generator, or 44Sc (T½ = 3.97 h) from the 44Ti/44Sc generator.rnIn this thesis the implementation of radioactive gallium-68 and scandium-44 for molecular imaging and nuclear medical diagnosis, beginning with chemical separation and purification of 44Ti as a radionuclide mother, investigation of pilot generators with different elution mode, building a prototype generator, development and investigation of post-processing of the generator eluate, its concentration and further purification, the labeling chemistry under different conditions, in vitro and in vivo studies of labeled compounds and, finally, in vivo imaging experiments are described.