999 resultados para Gentz, Friedrich von, 1764-1832.


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Vorbesitzer: Georg Friedrich von Ramingen;

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Vorbesitzer: Georg Friedrich von Ramingen

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Transcription factors control eukaryotic polymerase II function by influencing the recruitment of multiprotein complexes to promoters and their subsequent integrated function. The complexity of the functional ‘transcriptosome’ has necessitated biochemical fractionation and subsequent protein sequencing on a grand scale to identify individual components. As a consequence, much is now known of the basal transcription complex. In contrast, less is known about the complexes formed at distal promoter elements. The c-fos SRE, for example, is known to bind Serum Response Factor (SRF) and ternary complex factors such as Elk-1. Their interaction with other factors at the SRE is implied but, to date, none have been identified. Here we describe the use of mass-spectrometric sequencing to identify six proteins, SRF, Elk-1 and four novel proteins, captured on SRE duplexes linked to magnetic beads. This approach is generally applicable to the characterisation of nucleic acid-bound protein complexes and the post-translational modification of their components.

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Mode of access: Internet.

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Includes index.

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"Originally printed in the 'National Review, ' February, 1900."

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Translation of: Die Leiden des jungen Werther.

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Sechzigster Band. 1842. VIII [i.e. VI], [2], 338 p.

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Mode of access: Internet.

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Einleitendes: Literarische Vorgeschichte des Problems. Periodisierung.--Platens Verhältnis zu Goethe in seiner Entwicklung: Erste periode. Bis 1816. Die letzten Münchner Jahre (1816-1818) Die Würzburger und beginnende Erlanger Zeit (1819-1820) Die Erlanger Zeit (bis 1826) Die italienische Periode (1826-1835)--Anhang: Goethe über Platen.-- Beilagen (1-12)