Conception optimale d’une chaîne de traction électrique pour une voiture de type Formule SAE

La Formule SAE (Society of Automotive Engineers) est une compétition étudiante consistant en la conception et la fabrication d’une voiture de course monoplace. De nombreux événements sont organisés à chaque année au cours desquels plusieurs universités rivalisent entre elles lors d’épreuves dynamiques et statiques. Celles-ci comprennent l’évaluation de la conception, l’évaluation des coûts de fabrication, l’accélération de la voiture, etc. Avec plus de 500 universités participantes et des événements annuels sur tous les continents, il s’agit de la plus importante compétition d’ingénierie étudiante au monde. L’équipe ULaval Racing a participé pendant plus de 20 ans aux compétitions annuelles réservées aux voitures à combustion. Afin de s’adapter à l’électrification des transports et aux nouvelles compétitions destinées aux voitures électriques, l’équipe a conçu et fabriqué une chaîne de traction électrique haute performance destinée à leur voiture 2015. L’approche traditionnelle employée pour concevoir une motorisation électrique consiste à imposer les performances désirées. Ces critères comprennent l’inclinaison maximale que la voiture doit pouvoir gravir, l’autonomie désirée ainsi qu’un profil de vitesse en fonction du temps, ou tout simplement un cycle routier. Cette approche n’est malheureusement pas appropriée pour la conception d’une traction électrique pour une voiture de type Formule SAE. Ce véhicule n’étant pas destiné à la conduite urbaine ou à la conduite sur autoroute, les cycles routiers existants ne sont pas représentatifs des conditions d’opération du bolide à concevoir. Ainsi, la réalisation de ce projet a nécessité l’identification du cycle d’opération routier sur lequel le véhicule doit opérer. Il sert de point de départ à la conception de la chaîne de traction composée des moteurs, de la batterie ainsi que des onduleurs de tension. L’utilisation d’une méthode de dimensionnement du système basée sur un algorithme d’optimisation génétique, suivie d’une optimisation locale couplée à une analyse par éléments-finis a permis l’obtention d’une solution optimale pour les circuits de type Formule SAE. La chaîne de traction conçue a été fabriquée et intégrée dans un prototype de voiture de l’équipe ULaval Racing lors de la saison 2015 afin de participer à diverses compétitions de voitures électriques.

Design, modelling, simulation and integration of cyber physical systems: methods and applications

The main drivers for the development and evolution of Cyber Physical Systems (CPS) are the reduction of development costs and time along with the enhancement of the designed products. The aim of this survey paper is to provide an overview of different types of system and the associated transition process from mechatronics to CPS and cloud-based (IoT) systems. It will further consider the requirement that methodologies for CPS-design should be part of a multi-disciplinary development process within which designers should focus not only on the separate physical and computational components, but also on their integration and interaction. Challenges related to CPS-design are therefore considered in the paper from the perspectives of the physical processes, computation and integration respectively. Illustrative case studies are selected from different system levels starting with the description of the overlaying concept of Cyber Physical Production Systems (CPPSs). The analysis and evaluation of the specific properties of a sub-system using a condition monitoring system, important for the maintenance purposes, is then given for a wind turbine.

Diseño de una herramienta modular que facilite la implementación del Banco de Proyectos de la Fundación Red de Apoyo Social de Antioquia – RASA, ubicado en la ciudad de Medellín, entre el periodo 2014-2 y 2015-1

Los usuarios reales y potenciales del sistemas de salud en Colombia, encuentran en el camino de acceso a los servicios múltiples barreras, debido a las diferentes carencias que éste sistema presenta. Para apoyar las necesidades del usuario en éste tema de acceso, se constituyó en el año 2006 la Fundación RASA, quien ofrece de manera gratuita, a la comunidad en general, mecanismos de exigibilidad, acceso y protección de sus derechos en temas de salud. Este trabajo de grado, pretende dar un valor agregado diseñando una herramienta modular que facilite la implementación del banco de proyectos, con el fin de mejorar sus procesos y sea referencia para otras entidades dedicadas a velar por el bienestar de los individuos, en virtud de su objeto social orientado a la protección de derechos en temas de salud, además se realiza con el fin de Optar por el Título de Especialista en Alta Gerencia de la Universidad de Medellín. Con el fin de entender las necesidades de La Fundación RASA, será primordial conocer y tener un manejo adecuado de la teoría de la organización; teniendo clara su vertiente descriptiva que sugiere lo que se debe hacer para mejorar varios aspectos de la empresa, en éste caso la necesidad de diseñar un Banco de Proyectos. El trabajo se ha estructurado de la siguiente manera: Referente Teórico, Contextualización De La Fundación Rasa, Diseño De Una Herramienta Modular (Introducción, Objetivos, Recursos, Metodología y procedimientos, Evaluación y Monitoreo, Responsable de proceso, Presupuesto Estructural), Conclusiones y Recomendaciones.

The PROSPER Toolkit

The PROSPER (Proof and Specification Assisted Design Environments) project advocates the use of toolkits which allow existing verification tools to be adapted to a more flexible format so that they may be treated as components. A system incorporating such tools becomes another component that can be embedded in an application. This paper describes the PROSPER Toolkit which enables this. The nature of communication between components is specified in a language-independent way. It is implemented in several common programming languages to allow a wide variety of tools to have access to the toolkit.

Photonic integrated circuits development: a universal transceiver for NG-PON2

In the last years there has been a clear evolution in the world of telecommunications, which goes from new services that need higher speeds and higher bandwidth, until a role of interactions between people and machines, named by Internet of Things (IoT). So, the only technology able to follow this growth is the optical communications. Currently the solution that enables to overcome the day-by-day needs, like collaborative job, audio and video communications and share of les is based on Gigabit-capable Passive Optical Network (G-PON) with the recently successor named Next Generation Passive Optical Network Phase 2 (NG-PON2). This technology is based on the multiplexing domain wavelength and due to its characteristics and performance becomes the more advantageous technology. A major focus of optical communications are Photonic Integrated Circuits (PICs). These can include various components into a single device, which simpli es the design of the optical system, reducing space and power consumption, and improves reliability. These characteristics make this type of devices useful for several applications, that justi es the investments in the development of the technology into a very high level of performance and reliability in terms of the building blocks. With the goal to develop the optical networks of future generations, this work presents the design and implementation of a PIC, which is intended to be a universal transceiver for applications for NG-PON2. The same PIC will be able to be used as an Optical Line Terminal (OLT) or an Optical Network Unit (ONU) and in both cases as transmitter and receiver. Initially a study is made of Passive Optical Network (PON) and its standards. Therefore it is done a theoretical overview that explores the materials used in the development and production of this PIC, which foundries are available, and focusing in SMART Photonics, the components used in the development of this chip. For the conceptualization of the project di erent architectures are designed and part of the laser cavity is simulated using Aspic™. Through the analysis of advantages and disadvantages of each one, it is chosen the best to be used in the implementation. Moreover, the architecture of the transceiver is simulated block by block through the VPItransmissionMaker™ and it is demonstrated its operating principle. Finally it is presented the PIC implementation.

THE FEASIBILITY OF USING WEB-BASED TECHNOLOGY FOR THE MANAGEMENT OF DREDGING PROJECTS

The research investigates the feasibility of using web-based project management systems for dredging. To achieve this objective the research assessed both the positive and negative aspects of using web-based technology for the management of dredging projects. Information gained from literature review and prior investigations of dredging projects revealed that project performance, social, political, technical, and business aspects of the organization were important factors in deciding to use web-based systems for the management of dredging projects. These factors were used to develop the research assumptions. An exploratory case study methodology was used to gather the empirical evidence and perform the analysis. An operational prototype of the system was developed to help evaluate developmental and functional requirements, as well as the influence on performance, and on the organization. The evidence gathered from three case study projects, and from a survey of 31 experts, were used to validate the assumptions. Baselines, representing the assumptions, were created as a reference to assess the responses and qualitative measures. The deviation of the responses was used to evaluate for the analysis. Finally, the conclusions were assessed by validating the assumptions with the evidence, derived from the analysis. The research findings are as follows: 1. The system would help improve project performance. 2. Resistance to implementation may be experienced if the system is implemented. Therefore, resistance to implementation needs to be investigated further and more R&D work is needed in order to advance to the final design and implementation. 3. System may be divided into standalone modules in order to simplify the system and facilitate incremental changes. 4. The QA/QC conceptual approach used by this research needs to be redefined during future R&D to satisfy both owners and contractors. Yin (2009) Case Study Research Design and Methods was used to develop the research approach, design, data collection, and analysis. Markus (1983) Resistance Theory was used during the assumptions definition to predict potential problems to the implementation of web-based project management systems for the dredging industry. Keen (1981) incremental changes and facilitative approach tactics were used as basis to classify solutions, and how to overcome resistance to implementation of the web-based project management system. Davis (1989) Technology Acceptance Model (TAM) was used to assess the solutions needed to overcome the resistances to the implementation of web-base management systems for dredging projects.

Preparation and In Vitro Release of Drug-Loaded Microparticles for Oral Delivery Using Wholegrain Sorghum Kafirin Protein

Kafirin microparticles have been proposed as an oral nutraceutical and drug delivery system. This study investigates microparticles formed with kafirin extracted from white and raw versus cooked red sorghum grains as an oral delivery system. Targeted delivery to the colon would be beneficial for medication such as prednisolone, which is used in the management of inflammatory bowel disease. Therefore, prednisolone was loaded into microparticles of kafirin from the different sources using phase separation. Differences were observed in the protein content, in vitro protein digestibility, and protein electrophoretic profile of the various sources of sorghum grains, kafirin extracts, and kafirin microparticles. For all of the formulations, the majority of the loaded prednisolone was not released in in vitro conditions simulating the upper gastrointestinal tract, indicating that most of the encapsulated drug could reach the target area of the lower gastrointestinal tract. This suggests that these kafirin microparticles may have potential as a colon-targeted nutraceutical and drug delivery system.

Formulation and nebulization of fluticasone propionate-loaded lipid nanocarriers.

International audience

Miradouro Virtual(R)

Esta tese pretende descrever o desenvolvimento e arquitectura do software que constitui o Miradouro Virtual@, mais especificamente do componente referente à interface. O Miradouro Virtual@ é um dispositivo cujo propósito à semelhança dos tradicionais binóculos turísticos, é observar a paisagem, mas cuja interacção não está limitada à simples observação individual. Recorre à realidade aumentada para sobrepôr imagens geradas por computador a imagens reais, capturadas por um dispositivo para aquisição de imagem real (tipicamente uma câmara de vídeo), e mostra-as num ecrã touchscreen, permitindo deste modo, combinar elementos virtuais e multimédia com a paisagem real. A imagem final, composta, dá ao utilizador uma nova dimensão do espaço envolvente, permitindo-lhe explorar uma nova camada de informação não visível anteriormente. Sendo sensíveis à orientação do Miradouro Virtual@, os elementos virtuais e multimédia adaptam-se de acordo com os movimentos do dispositivo. O Miradouro Virtual@ é um produto composto por diversos elementos de hardware e software. O foco desta tese recai apenas nos componentes de software, mais especificamente na interface. Pretende dar a conhecer as limitações da versão anterior do software e mostrar as soluções encontradas que permitiram ultrapassar algumas dessas limitações. ABSTRACT; This thesis focuses on the design and development of the Virtual Sightseeing™ software, more specifically on the interface component. The Virtual Sightseeing™ is a device similar to the traditional scenic viewers that takes advantage of its generally known and popularity to build an innovative system. It works by using augmented reality to superimpose, in real-time, images generated by a computer onto a live stream captured by a video camera and displaying them on a touchscreen display. It allows adding multimedia elements to the real scenery by composing them in the image that is presented to the user. The multimedia information and virtual elements that are displayed are sensitive to the orientation and position of the device. They change as the user manually changes the orientation of the device. The Virtual Sightseeing™ is comprised of several hardware and software components. The focus of this thesis is on the software part, more specifically on the interface component. It intends to show the known limitations of the previous software version and how they were overcome in this new version.

Efeito da associação do herbicida clomazone a nanoesferas de alginato/quitosana na sorção em solos

Agrochemicals constitute the class of products most commonly found in water resources. Their high level of concentration is due to the fact that less than 0.1% of pesticides applied to crops reach their target. The present work aims to study the sorption of clomazone herbicide (associated or not with nanoparticles). The sorption tests, performed with the 2(4) factorial design, showed that the form of herbicide is the main factor for sorption of clomazone. The application of nanoparticles as delivery system for agrochemicals is a pressing area of study and can contribute for decrease in effects of clomazone in the environment.

Avaliação da carga de trabalho de enfermagem na unidade de cuidados intensivos Dr. Emílio Moreira em Portalegre

No âmbito do 4º Mestrado em Enfermagem com Especialização em Gestão de Unidades de Saúde, da Escola Superior de Saúde do Instituto Politécnico de Portalegre, o presente relatório pretende apresentar um documento reflexivo sobre a aquisição e o desenvolvimento de competências na área da gestão de unidades de saúde, em âmbito de estágio. O estágio decorreu na Unidade de Cuidados Intensivos Dr. Emílio Moreira da Unidade Local do Norte Alentejano, no período de Outubro de 2015 a Fevereiro de 2016. Foi aplicada a metodologia de projeto, tendo desenvolvido no decorrer do estágio o Trabalho de Projeto Avaliação da Carga de Trabalho de Enfermagem na Unidade de Cuidados Intensivos Dr. Emílio Moreira em Portalegre Os enfermeiros desempenham funções muito importantes na área da gestão dos recursos e dos cuidados, em unidades de cuidados intensivos. Uma dessas funções consiste em avaliar o índice de gravidade dos doentes internados e a carga de trabalho de enfermagem através do Therapeutic Intervention Scoring System-28. Neste sentido tornou-se pertinente o estudo retrospetivo da carga de trabalho na UCIDEM, por forma a otimizar a utilização do instrumento de gestão implementado e propor melhorias no âmbito da dotação dos enfermeiros. Concluiu-se, principalmente, que: em relação ao Índice de Enfermeiros e Score TISS, verificaram-se variações acentuadas, quer na necessidade de trabalho de enfermagem quer na gravidade dos doentes, durante 365 dias; comparando a média anual de TISS obtida com o diagnóstico atual da situação na UCIDEM, existe uma dotação desfasada de acordo com o que foi medido pelo TISS; e que a carga de trabalho dos enfermeiros não é distribuída equitativamente pelos turnos

Síntese e caracterização do poli(ácido láctico) para potencial uso em sistemas de liberação controlada de fármacos

With the advances in medicine, life expectancy of the world population has grown considerably in recent decades. Studies have been performed in order to maintain the quality of life through the development of new drugs and new surgical procedures. Biomaterials is an example of the researches to improve quality of life, and its use goes from the reconstruction of tissues and organs affected by diseases or other types of failure, to use in drug delivery system able to prolong the drug in the body and increase its bioavailability. Biopolymers are a class of biomaterials widely targeted by researchers since they have ideal properties for biomedical applications, such as high biocompatibility and biodegradability. Poly (lactic acid) (PLA) is a biopolymer used as a biomaterial and its monomer, lactic acid, is eliminated by the Krebs Cycle (citric acid cycle). It is possible to synthesize PLA through various synthesis routes, however, the direct polycondensation is cheaper due the use of few steps of polymerization. In this work we used experimental design (DOE) to produce PLAs with different molecular weight from the direct polycondensation of lactic acid, with characteristics suitable for use in drug delivery system (DDS). Through the experimental design it was noted that the time of esterification, in the direct polycondensation, is the most important stage to obtain a higher molecular weight. The Fourier Transform Infrared (FTIR) spectrograms obtained were equivalent to the PLAs available in the literature. Results of Differential Scanning Calorimetry (DSC) showed that all PLAs produced are semicrystalline with glass transition temperatures (Tgs) ranging between 36 - 48 °C, and melting temperatures (Tm) ranging from 117 to 130 °C. The PLAs molecular weight characterized from Size Exclusion Chromatography (SEC), varied from 1000 to 11,000 g/mol. PLAs obtained showed a fibrous morphology characterized by Scanning Electron Microscopy (SEM)

Bionano Electronics: Magneto-Electric Nanoparticles for Drug Delivery, Brain Stimulation and Imaging Applications

Nanoparticles are often considered as efficient drug delivery vehicles for precisely dispensing the therapeutic payloads specifically to the diseased sites in the patient’s body, thereby minimizing the toxic side effects of the payloads on the healthy tissue. However, the fundamental physics that underlies the nanoparticles’ intrinsic interaction with the surrounding cells is inadequately elucidated. The ability of the nanoparticles to precisely control the release of its payloads externally (on-demand) without depending on the physiological conditions of the target sites has the potential to enable patient- and disease-specific nanomedicine, also known as Personalized NanoMedicine (PNM). In this dissertation, magneto-electric nanoparticles (MENs) were utilized for the first time to enable important functions, such as (i) field-controlled high-efficacy dissipation-free targeted drug delivery system and on-demand release at the sub-cellular level, (ii) non-invasive energy-efficient stimulation of deep brain tissue at body temperature, and (iii) a high-sensitivity contrasting agent to map the neuronal activity in the brain non-invasively. First, this dissertation specifically focuses on using MENs as energy-efficient and dissipation-free field-controlled nano-vehicle for targeted delivery and on-demand release of a anti-cancer Paclitaxel (Taxol) drug and a anti-HIV AZT 5’-triphosphate (AZTTP) drug from 30-nm MENs (CoFe2O4-BaTiO3) by applying low-energy DC and low-frequency (below 1000 Hz) AC fields to separate the functions of delivery and release, respectively. Second, this dissertation focuses on the use of MENs to non-invasively stimulate the deep brain neuronal activity via application of a low energy and low frequency external magnetic field to activate intrinsic electric dipoles at the cellular level through numerical simulations. Third, this dissertation describes the use of MENs to track the neuronal activities in the brain (non-invasively) using a magnetic resonance and a magnetic nanoparticle imaging by monitoring the changes in the magnetization of the MENs surrounding the neuronal tissue under different states. The potential therapeutic and diagnostic impact of this innovative and novel study is highly significant not only in HIV-AIDS, Cancer, Parkinson’s and Alzheimer’s disease but also in many CNS and other diseases, where the ability to remotely control targeted drug delivery/release, and diagnostics is the key.

Evaluating Methods of Calculating the Fixed Fee on Professional Service Contracts

The South Carolina Department of Transportation routinely retains Professional Consulting Engineering firms to provide engineering design and related professional services for the preparation of construction plans or design-build Request for Proposal bid packages for a wide variety of Federal-aid Highway Program roadway and bridge construction projects throughout South Carolina.The purpose of this project is to examine the current process of determining a "Fair and Reasonable" fixed fee for professional service contracts and to evaluate possible alternative methods including practices in other states that may improve the process, particularly in light of the considerable variation in audited overhead rates among consulting firms. In reviewing such alternative methods particular attention will be given to evaluating the potential impact of the method as an incentive to consulting firms to effectively manage their overhead costs.

"Lo Nuestro"

Lo Nuestro SAS es una empresa constituida por tres emprendedores que buscan volver más eficiente el sistema domiciliario de las tiendas de barrio, utilizando las tecnologías de la información, con la finalidad de fortalecer tanto a los consumidores como a los vendedores (tenderos). El potencial del concepto permite que a futuro nos posicionemos como una empresa líder e innovadora en el sector, brindado facilidades optimizadoras de servicio que beneficiara al productor, al intermediario y al consumidor final. Finalidad que se logra al ser el servicio más efectivo y de primera mano que entiende los tenderos y al consumidor final. Por consiguiente, y apalancándonos en las tecnologías de la información, a través de una red de ciclistas constituida por gente joven interesada en obtener ingresos extra. Estos se organizan de acuerdo al pacto entre el consumidor, el tendero, la empresa y ciclista, que bien se facilita a través de las características de la plataforma virtual. De acuerdo a lo ya planteado, el proyecto se expone no solo como un atractivo tanto para el tendero común y sus usuarios, sino además para todas las personas que estén interesadas en recibir una remuneración extra por sus servicios de domicilio.