Distribution of molluscs on the Atlantic continental shelf off Southern Spanish Sahara, West Africa

Two hundred and seventy five mollusc species from the continental shelf off Southern Spanish Sahara (depth: 32-60 m) were identified. Their distribution pattern is strongly influenced by the nature of the bottom (firm substrate, shelter, stability of sediment) rather than other factors at that depth interval. This faunal assemblage shows great affinity to the Mediterranean and Lusitanian faunas, and comprises only few (22 %) exclusively Senegalese and species living south of Senegal.

Composition of bitumen in the organic matter of Black Sea sediments from DSDP Hole 42-379B

Bituminologic analysis of sediment cores from the Black Sea (water depth up to 2000 m, drilling depth up to 625 m) has revealed all components typical for fossilized rocks, viz. hydrocarbons, resins, asphaltenes, and insoluble matter. Proportions of these components, their composition and properties do not display any dependence on depth in hole and seem to be governed by composition of organic matter and conditions and degree of its transformation at early stages of lithogenesis.

X-ray fluorescence scannings, diatoms, and dinocyst of ODP Site 189-1172

Eocene sediments drilled at the East Tasman Plateau (ETP) exhibit well-defined cycles, high-resolution magnetic stratigraphy, and environmentally-controlled dinoflagellate and diatom distribution patterns. We derive a cyclostratigraphy from the spectral analysis of high-resolution elemental concentration records (Ca, Fe) for this shallow marine time series spanning the middle to early late Eocene (C16n.2n - C21). Changes in carbonate content, the ratio between Gonyaulacoid and Peridinioid dinocysts, and relative abundance of "oligotrophic" diatoms serve as proxies for a high-resolution climatic and sea-level history with high values representing high sea-level stands and decreased eutrophy of surface waters. Changing ratios between high latitude dinocysts versus cosmopolitan species provide clues on sea surface temperature trends and water mass exchange. Our results show that the relatively shallow-water middle Eocene environments of the ETP are influenced by orbitally-forced climatic cycles superimposed on third order relative sea-level changes. Changes in the dominance of Milankovitch frequency at ~38.6 Ma (late Eocene) is related to an initial deepening-step within the Tasmanian Gateway prior to the major deepening during the middle late Eocene (~35.5 Ma). Decreasing sedimentation rates at 38 Ma and 37.2 Ma reflect winnowing associated with sea-level fall. This episode is followed by renewed transgression. Dinocyst distribution patterns indicate high latitude, probably cool temperate surface water conditions throughout, with the exception of a sudden surge in cosmopolitan species near the base of subchron C18.2r, at ~41 Ma; this event is tentatively correlated to the Middle Eocene Climatic Optimum.

Economic impact assessment of a chlorofluorocarbon production cap : support document, section 6, proposed rule, Toxic Substances Control Act /

"Contract no. 68-01-6236."

Temunat Doryan Gri /

With: Tolstoy, Leo, garf, 1828-1910. Anah Ḳareninah.

De asse et partibus eius libri quinq[ue] /

Renouard (Badius),

Dramen /

1. bd. Profesor Brener. Yeder mit zayn got . Beser nisht geboren v eren. Di mut er. Glik fergesene. Yesurim -- 2. bd. Der oytser. Der fonograf. Der got fun dem raykh gev orenem v olhendler. Der dolar. Der erfinder un dem k enigs t okht er. Polit ik . K layne helden. Di sheyne none -- Bd. 3. Der fremder. Der sht umer meshiyeh . Di familiye Tsevi. Ayzik Sheft el -- 4. bd. Yenk el der shmied. Gavri un di froyen. Mit ziegerfohnen. Liebe's k rume v egen -- 5. bd. Dov id ha-meylekh un zayne v ayber. Adonyohu. Miryam fun Magdelah. Nina Morden's liebes. Gev isen. Di bergsht ayger.

K literaturnoĭ istorīi drevne-russkikh sbornikov. Opyt izsli͡edovanii͡a "Izmaragda.

Title on cover: K literaturnoj istorii drevne-russkich sbornikov.

Sefer Ṿikuaḥ ha-Ramban : be-ʻinyan ha-emunah li-fene melekh ṿe-śarim u-veʼur Ramban ʻal Hineh yaśkil ʻavdi /

Mode of access: Internet.

Miḳraʾot gedolot : ʻim 32 perushim = Mikraet gedalet, t.e., Sv. Pisanı̄e s kommentarı̄i︠a︡mi.

Vols. 2-6, 8 published by V. b. Z. Yaʻbets and Y. L. Shṭain, v. 7 published by N. Shrifṭgiser, v. 12 printed by Y. Goldman.

Report

Two issues of report for <1865/67, 1877/79-1879/80> printed in San Francisco and Sacramento respectively

Ḥeḳer halakhah : ...sheʼelot u-teshuvot...be-shiṭot ha-Shas u-fosḳim...

No more published.

Characterizing Healthcare Utilization, Direct Costs, and Comorbidities Associated with Interstitial Cystitis: A Retrospective Claims Analysis

Thesis (Master's)--University of Washington, 2016-06

IGF-1 phosphorylates AMPK-alpha subunit in ATM-dependent and LKB1-independent manner

Serine/threonine protein kinase AMP-activated protein kinase (AMPK) is a key metabolic stress-responsive factor that promotes the adaptation of cells to their microenvironment. Elevated concentrations of intracellular AMP, caused by metabolic stress, are known to activate AMPK by phosphorylation of the catalytic subunit. Recently, the tumor suppressor serine/threonine protein kinase LKB1 was identified as an upstream kinases, AMPKKs. In the current study, we found that stimulation with growth factors also caused AMPK-alpha subunit phosphorylation. Interestingly, even an LKB1-nonexpressing cancer cell line, HeLa, exhibited growth factor-stimulated AMPK-alpha subunit phosphorylation, suggesting the presence of an LKB1-independent pathway for AMPK-alpha subunit phosphorylation. In the human pancreatic cancer cell line PANC-1, AMPK-alpha subunit phosphorylation promoted by IGF-I was suppressed by antisense ataxia telangiectasia mutated (ATM) expression. We found that IGF-1 also induced AMPK-alpha subunit phosphorylation in the human normal fibroblast TIG103 cell line, but failed to do so in a human fibroblast AT2-KY cell line lacking ATM. Immunoprecipitates of ATM collected from IGF-1-stimulated cells also caused the phosphorylation of the AMPK-alpha subunit in vitro. IGF-1-stimulated ATM phosphorylation at both threonine and tyrosine residues, and our results demonstrated that the phosphorylation of tyrosine in the ATM molecule is important for AMPK-alpha subunit phosphorylation during IGF-1 signaling. These results suggest that IGF-1 induces AMPK-alpha subunit phosphorylation via an ATM-dependent and LKB1-independent pathway. (C) 2004 Elsevier Inc. All rights reserved.