Use of molecular epidemiology to monitor the nosocomial dissemination of methicillin-resistant Staphylococcus aureus in a University Hospital from 1991 to 2001

Methicillin-resistant Staphylococcus aureus (MRSA) has been the cause of major outbreaks and epidemics among hospitalized patients, with high mortality and morbidity rates. We studied the genomic diversity of MRSA strains isolated from patients with nosocomial infection in a University Hospital from 1991 to 2001. The study consisted of two periods: period I, from 1991 to 1993 and period II from 1995 to 2001. DNA was typed by pulsed-field gel electrophoresis and the similarity among the MRSA strains was determined by cluster analysis. During period I, 73 strains presented five distinctive DNA profiles: A, B, C, D, and E. Profile A was the most frequent DNA pattern and was identified in 55 (75.3%) strains; three closely related and four possibly related profiles were also identified. During period II, 80 (68.8%) of 117 strains showed the same endemic profile A identified during period I, 18 (13.7%) closely related profiles and 18 (13.7%) possibly related profiles and, only one strain presented an unrelated profile. Cluster analysis showed a 96% coefficient of similarity between profile A from period I and profile A from period II, which were considered to be from the same clone. The molecular monitoring of MRSA strains permitted the determination of the clonal dissemination and the maintenance of a dominant endemic strain during a 10-year period and the presence of closely and possibly related patterns for endemic profile A. However, further studies are necessary to improve the understanding of the dissemination of the endemic profile in this hospital.

Qual o valor do auto-interesse?

The article critically reviews past and current justifications for the theoretical use of the behavioral assumption of self-interest, explanatory, normative, representational and critical, focusing on the critical function. This latter emerges from an incursion into the modern history of ideas and may be shown still to fertilize a number of contemporary economic approaches.

La Distracción de Sí. Jacques Derrida y la Auto-Afección

En este texto buscamos hacer inteligible el lugar y los derroteros que sigue el concepto de auto-afección en el pensamiento de Jacques Derrida. Dicho concepto se desarrolla a partir de una interpretación de Kant y el problema de la metafísica, de Heidegger. En la elaboración del concepto en Derrida se enfatiza el momento de distancia en el que el sí-mismo no puede reducir al otro, sino que tiene que hacer patente la demora en su propia formación. Esto implicaría considerar que la mismidad que se constituye en la auto-afección no puede ser separada de una hetero-afección, mediante la cual el otro no puede ser objetivado y no es otra cosa que el sí-mismo en su alteración. La forma de dicho espaciamiento que produce la alteración se pone a prueba en la voz y en la estructura del “oírse-hablar”, la que se revela como un espacio polifónico irreductible a una unidad, donde la auto-afección se desune de sí para retornar como aquello que no espera y como aquello que no puede replegarse en un lugar de reunión.

28/3/20, Parc des Princes, arrivée de Gaston Huet [i.e. Heuet], gagnant du cross populaire de l'Auto : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58667

Parc des Princes, 28/3/20, départ du cross populaire de l'Auto : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58668

28/3/20, Gaston Huet [i.e. Heuet], gagnant du cross populaire de l'Auto : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58669

28/3/20, Parc des Princes, Gaston Huet [i.e. Heuet], gagnant du cross populaire de l'Auto : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 58670

En auto, des promeneurs écoutent un concert par TSF : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 59917

Robert Breese possède la plus petite auto du monde : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60117

Auto-car Cook : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60260

Auto Ganemain [?] : [photographie de presse] / [Agence Rol]

Référence bibliographique : Rol, 60003