De usu scientiae naturalis in oeconomia

Invocatio: D.D.

L'Univers

1870/08/22 (Numéro 1201).

Detection, Identification and Molecular Variation of Human Enteroviruses

Picornaviruses are the most common human viruses and the identification of the picornaviruses is nowadays based on molecular techniques, for example, reverse transcriptase polymerase chain reaction (RT-PCR). One aim of this thesis was to improve the identification of picornaviruses, especially rhino- and enteroviruses, with a real-time assay format and, also, to improve the differentiation of the viruses with genus-specific locked nucleic acid (LNA) probes. Another aim was to identify and study the causative agent of the enterovirus epidemics that appeared in Finland during seasons 2008-2010. In this thesis, the first version of picornavirus qRT-PCR with a melting curve analysis was used in a study of rhinovirus transmission within families with a rhinovirus positive index child where rhinovirus infection was monitored in all family members. In conclusion, rhinoviruses spread effectively within families causing mostly symptomatic infections in children and asymptomatic infections in adults. To improve the differentiation between rhino- and enterovirus the picornavirus qRT-PCR was modified with LNA-incorporated probes. The LNA probes were validated with picornavirus prototypes and different clinical specimen types. The LNA probe-based picornavirus qRT-PCR was able to differentiate all rhino- and enteroviruses correctly, which makes it suitable for diagnostic use. Moreover, in this thesis enterovirus outbreaks were studied with a well-observed method to create a strain-specific qRT-PCR from the typing region VP1 protein. In a hand-foot-and-mouth-disease (HFMD) outbreak in 2008, the causative agent was identified as CV-A6 and when the molecular evolution of the new HFMD CV-A6 strain was studied it was found that CV-A6 was the emerging agent for HFMD and onychomadesis. Furthermore, unusual E-30 meningitis epidemics that apeared during seasons 2009 and 2010 were studied with strain-specific qRT-PCR. The E-30 affected mostly adolescents and was probably spread in sports teams.

Intelligence in peace support operations

Finnish Defence Studies is published under the auspices of the National Defence College, and the contributions reflect the fields of research and teaching of the College. Finnish Defence Studies will occasionally feature documentation on Finnish Security Policy. Views expressed are those of the authors and do not necessarily imply endorsement by the National Defence College.

Le Petit journal. Supplément du dimanche

1913/11/23 (Numéro 1201).

« Li Livre dou Bret », ou Le Roman de Tristan [de LUCE DU GAST].

Commençant par : «... voluntez d'Elinde et landemain quant il fut ajornez... » et finissant par : «... et plairai tant com li mondes durrai, li quex est apelez li Livres dou Bret. Explicit li Livres dou Bret. Amen » . D'après l'épilogue, « HELYE DE BERRON » aurait remanié le travail de LUCE DU GAST, qu'il a divisé en trois livres. Voir l'introduction au livre III, fol. 264. Manque le premier feuillet de chaque livre.

Roman de Tristan, en prose, par LUCE DE GAST.

Incomplet de la fin. — Miniatures.

L'Écho de Paris

1887/07/01 (Numéro 1201).

Vetus Testamentum cum glossa ordinaria, pars.

Avec arguments. Cant. canticorum V,11-VIII,14 (1) ; Osee I,3-XIV,10 (9) ; Joel I,6-III,21 (38) ; Amos I,1-IX,15 (48) ; Abdias I,7-21 (68) ; Jonas I,1-IV,11 (70v) ; Mich. I,6-VII,20 (77) ; Nahum I,1-III,19 (89v) ; Habacuc I,2-III,19 (95) ; Sophonias I,1-III,20 (102v) ; Agg. I,2-II,24 (110) ; Zachar. I,3-XIV,21 (115) ; Malach. I,4-IV,6 (139).

Biblia sacra.

Avec prologues et arguments. Genesis (7v), etc. — Oratio Manasse (167) ; Esdras I-III (167v), etc. — Macchab. I-II, avec prologues de RABAN MAUR (353v, 354). — Evang. Matthaei (377), etc. — XIV Epist. Pauli (421v) ; Actus Apost. (448v) ; VII Epist. canon. (462) ; Apocalypsis (467v). — Interpretationes nominum hebraicorum : « Aaz, apprehendens... — ... consiliatores eorum. » (473v). — « Ordo librorum presentis voluminis. » (513v).

Biblia sacra, pars.

Avec prologues et arguments. Genesis (3) ; Reg. I-IV (13) ; Tobias (43) ; Job (45) ; Proverbia (51), etc. — Oratio Salomonis (70v) ; Isaias (71v), etc. — Daniel (99) ; Ezechiel (104v) ; XII Proph. min. (116). — Evang. Matthaei (130), etc. — XIV Epist. Pauli (156) ; Actus Apost. (172), etc. — Interpretationes nominum hebraicorum : « Aaz, apprehendens... — ... consiliatores eorum... secundum Jeronimum. » (188). F. 187 Fragment de liste des épîtres et évangiles, suivi d'hymnes ou proses à la Vierge : « Ave, virgo singularis, mundi splendor... », « Vas auri... », « Ave stella matutina ex qua... », « Oliva virens... », « Murenulis aureis rutilans... », « Mons altissimus... ».

Biblia sacra.

Avec prologues et arguments. Genesis (6), etc. — Oratio Manasse (170v) ; Esdras I-III (171v), etc. — Macchab. I-II, avec prologues de RABAN MAUR (360v). — Evang. Matthaei (382v), etc. — XIV Epist. Pauli (426) ; Actus Apost. (452v) etc. — Interpretationes nominum hebraicorum : « Aaz, apprehendens... — ... consiliatores eorum. » (477) ; « Abba, pater, Marci XIIII... — ... zizaniam. » (519). F. 1 et 2 Listes des livres de la Bible (XIIIe s.). F. 526 Liste des chefs d'Israël, de Moïse à Salomon, avec renvois à la Bible.

Biblia sacra.

Avec prologues et arguments. Genesis (3v), etc. — Oratio Manasse (158v) ; Esdras I-III (159), etc. — Macchab. I-II, avec prologues de RABAN MAUR (320). — Evang. Matthaei (340v), etc. — XIV Epist. Pauli (381v) ; Actus Apost. (406v), etc. — Interpretationes nominum hebraicorum : « Aaz, apprehendens... — ... consiliatores eorum. » (432). — « Liber ystorialis et florum totius Novi et Antiqui Testamenti. In Genesi sunt L capitula. In primo... — ... In XXVIII (Act. Apost.)... quidam crediderunt et quidam non. » (474). F. 430v et 431 En marge, recettes de médecine (XIVe-XVe s.). F. 431v Table des livres de la Bible (XIVe s.).

Biblia sacra, pars.

Avec prologues. Evang. Matthaei (2), Marci (45v), Lucae (72v), Johannis (116) ; Actus Apost. (148v) ; Apocalypsis (186v) ; VII Epist. canon. (205) ; XIV Epist. Pauli (222). F. 1v Addition : Ezechiel, XXXV, 1-5 et Jeremias, IV, 7. F. 305 Calendrier de Florence, avec des additions (dans le sens dominicain).

Novum Testamentum.

Evang. Matthaei (1), Marci (31), Lucae, cum argumento (49v, 240v), Johannis (82) ; Actus Apost. (107) ; XIV Epist. Pauli (140) ; VII Epist. canon. (203) ; Apocalypsis (220). F. 236 Calendrier d'Elne. F. 239v Comput. Ms. P de Wordsworth et White.