Kansanedustaja Raimo Ilaskivi 21/4 1975

Kirje 21.4.1975

Motor Vehicle Crash Fatalities for Week Ending, November 21, 2008

Motor Vehicle Crash Fatalities

EPI Update, November 21, 2008

Weekly newsletter for Center For Acute Disease Epidemiology of Iowa Department of Public Health.

Isolation and characterization of 21 microsatellite markers in the barn owl (Tyto alba).

We report 21 new polymorphic microsatellite markers in the European barn owl (Tyto alba). The polymorphism of the reported markers was evaluated in a population situated in western Switzerland and in another from Tenerife, Canary Islands. The number of alleles per locus varies between two and 31, and expected heterozygosity per population ranges from 0.16 to 0.95. All loci are in Hardy-Weinberg equilibrium and no linkage disequilibrium was detected. Two loci exhibit a null allele in the Tenerife population.

Comparison of human chromosome 21 conserved nongenic sequences (CNGs) with the mouse and dog genomes shows that their selective constraint is independent of their genic environment.

The analysis of conservation between the human and mouse genomes resulted in the identification of a large number of conserved nongenic sequences (CNGs). The functional significance of this nongenic conservation remains unknown, however. The availability of the sequence of a third mammalian genome, the dog, allows for a large-scale analysis of evolutionary attributes of CNGs in mammals. We have aligned 1638 previously identified CNGs and 976 conserved exons (CODs) from human chromosome 21 (Hsa21) with their orthologous sequences in mouse and dog. Attributes of selective constraint, such as sequence conservation, clustering, and direction of substitutions were compared between CNGs and CODs, showing a clear distinction between the two classes. We subsequently performed a chromosome-wide analysis of CNGs by correlating selective constraint metrics with their position on the chromosome and relative to their distance from genes. We found that CNGs appear to be randomly arranged in intergenic regions, with no bias to be closer or farther from genes. Moreover, conservation and clustering of substitutions of CNGs appear to be completely independent of their distance from genes. These results suggest that the majority of CNGs are not typical of previously described regulatory elements in terms of their location. We propose models for a global role of CNGs in genome function and regulation, through long-distance cis or trans chromosomal interactions.

Características del fitoplancton superficial en Paita, Chimbote, Callao, Pisco e Ilo (MOPAS 9510) 21 - 27 de octubre de 1995

Informa sobre los volúmenes de plancton superficial así como la distribución y composición especiológica de la comunidad fitoplanctónica, teniendo en consideración a los indicadores biológicos.

Opetusministeri Ulf Sundqvist 21/5 1973

Kirje 21.5.1973

Suurlähettiläs Joel Toivola 21/9 1974

Kirje 21.9.1974