999 resultados para Schwerin, Kurt Christoph von, Graf, 1684-1757.
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Signatur des Originals: S 36/F08558
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Freiherr [Karl Christoph] v. Mulzer
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von S. Silberstein
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von Fedor von Rauch
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Unterlage für diese Karte bilden in der Hauptsache Aufnahmen, die mit der Zweifach-Reihenbildkammer am 28. Juli 1931 in der Zeit von 6 Uhr 30 Min. MGZ. bis 9 Uhr 45 Min. aufgenommen worden sind. Außerdem sechs Aufnahmen mit der Handmeßkammer. Zur Ergänzung konnten 14 Aufnahmen der Panoramakammer herangezogen werden. Die Karte umfaßt einen nördlichen Teil vom Sund der Roten Armee bis zum Beginn des Matussewitsch-Sees mit einem Teil der Nordostküste und einen südlichen Teil mit Schokalski-Sund und dessen östlicher Begrenzung durch die Südinsel. Zwischen beiden Teilen der Karte klafft eine Lücke, hervorgerufen durch eine für die photographische Aufnahme undurchdringliche Nebeldecke.
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Teil 1, Abt.1**
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Metachromatic leukodystrophy is a lysosomal sphingolipid storage disorder caused by the deficiency of arylsulfatase A. The disease is characterized by progressive demyelination, causing various neurologic symptoms. Since no naturally occurring animal model of the disease is available, we have generated arylsulfatase A-deficient mice. Deficient animals store the sphingolipid cerebroside-3-sulfate in various neuronal and nonneuronal tissues. The storage pattern is comparable to that of affected humans, but gross defects of white matter were not observed up to the age of 2 years. A reduction of axonal cross-sectional area and an astrogliosis were observed in 1-year-old mice; activation of microglia started at 1 year and was generalized at 2 years. Purkinje cell dendrites show an altered morphology. In the acoustic ganglion numbers of neurons and myelinated fibers are severely decreased, which is accompanied by a loss of brainstem auditory-evoked potentials. Neurologic examination reveals significant impairment of neuromotor coordination.
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3
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2
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5
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bd. 3
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The eruption of Tambora (Indonesia) in April 1815 had substantial effects on global climate and led to the ‘Year Without a Summer’ of 1816 in Europe and North America. Although a tragic event — tens of thousands of people lost their lives — the eruption also was an ‘experiment of nature’ from which science has learned until today. The aim of this study is to summarize our current understanding of the Tambora eruption and its effects on climate as expressed in early instrumental observations, climate proxies and geological evidence, climate reconstructions, and model simulations. Progress has been made with respect to our understanding of the eruption process and estimated amount of SO2 injected into the atmosphere, although large uncertainties still exist with respect to altitude and hemispheric distribution of Tambora aerosols. With respect to climate effects, the global and Northern Hemispheric cooling are well constrained by proxies whereas there is no strong signal in Southern Hemisphere proxies. Newly recovered early instrumental information for Western Europe and parts of North America, regions with particularly strong climate effects, allow Tambora’s effect on the weather systems to be addressed. Climate models respond to prescribed Tambora-like forcing with a strengthening of the wintertime stratospheric polar vortex, global cooling and a slowdown of the water cycle, weakening of the summer monsoon circulations, a strengthening of the Atlantic Meridional Overturning Circulation, and a decrease of atmospheric CO₂. Combining observations, climate proxies, and model simulations for the case of Tambora, a better understanding of climate processes has emerged.
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Mode of access: Internet.
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Mode of access: Internet.