Motor Vehicle Accident Fatalities for the Week Ending, September 21, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, September 28, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Recurrent dominant mutations affecting two adjacent residues in the motor domain of the monomeric kinesin KIF22 result in skeletal dysplasia and joint laxity.

Spondyloepimetaphyseal dysplasia with joint laxity, leptodactylic type (lepto-SEMDJL, aka SEMDJL, Hall type), is an autosomal dominant skeletal disorder that, in spite of being relatively common among skeletal dysplasias, has eluded molecular elucidation so far. We used whole-exome sequencing of five unrelated individuals with lepto-SEMDJL to identify mutations in KIF22 as the cause of this skeletal condition. Missense mutations affecting one of two adjacent amino acids in the motor domain of KIF22 were present in 20 familial cases from eight families and in 12 other sporadic cases. The skeletal and connective tissue phenotype produced by these specific mutations point to functions of KIF22 beyond those previously ascribed functions involving chromosome segregation. Although we have found Kif22 to be strongly upregulated at the growth plate, the precise pathogenetic mechanisms remain to be elucidated.

Motor Vehicle Accident Fatalities for the Week Ending, October 5, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, October 12, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, October 26, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, November 2, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, November 16, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, November 30, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, November 21, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Projectos de Instalações em Edifícios

O presente relatório vem na sequência do trabalho desenvolvido durante aproximadamente nove meses no estágio efectuado na empresa Compasso Ecológico – Tecnologias Eco-eficientes para Edifícios Lda, Alcobaça, no âmbito do Mestrado em Instalações e Equipamentos em Edifícios do Instituto Superior de Engenharia de Coimbra. A Compasso Ecológico é uma empresa que tem por missão e área de actividade a realização de projectos de uma forma correcta e eficaz seguindo normas estabelecidas para que o projecto possa garantir conforto e segurança. No decorrer do estágio foram realizados vários projectos, sendo alguns deles feitos em grupo, estimulando-se assim o espírito de trabalho de equipa que é uma característica essencial de qualquer engenheiro na sua vida de trabalho activa. Foi tida sempre uma participação activa em todas as actividades desenvolvidas na empresa, conseguindo-se assim estar sempre a par das inovações tecnológicas e aprofundar os conhecimentos adquiridos durante o percurso académico de uma forma prática. As acções efectuadas durante o estágio, incidiram-se sobretudo na realização de projectos de Infra-estrutura de Telecomunicações em Edifícios (ITED), projectos de Instalações Eléctricas, projectos de Segurança Integrada, utilização do software Revit Mep para projectos de Aquecimento, Ventilação e Ar Condicionado (AVAC), realização de folhas de cálculo e vistorias às instalações.

Motor Vehicle Accident Fatalities for the Week Ending, December 14, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, December 28, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, December 14, 2007

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.

Motor Vehicle Accident Fatalities for the Week Ending, January 11, 2008

Record of the Fatalities for Motor Vehicle Accidents in Iowa per week.