Qué Peter Pan conocemos y cómo : Recorridos de un fenómeno intermedial desde su origen

En estas páginas haremos un rastreo de los orígenes, los cambios y las mutaciones del personaje y su historia hasta el modo en que lo conocimos y lo adoptamos como universal y nuestro a través de numerosos y diversos medios, como el cine, la televisión, el comic, el merchandising (por qué no), y los libros, por supuesto; pero también veremos que este niño que no quiere crecer ya nació volátil, inaprehensible, en la mente de J. M. Barrie, quien lo imaginó literario, teatral, cinematográfico, visual. ¿Quién es Peter Pan? ¿Qué imagen, idea, frase, se nos aparece apenas oímos ese nombre? ¿Será el pequeño bebé desnudo que habita los jardines de Kensington, los recorre montado en una cabra y actúa como orquesta de las hadas con la música de su flauta; o ese que se lleva a los hermanitos Darling a Nunca Jamás? ¿O será ese otro que viste de verde, como si fuera un Robin Hood niño, que todos, sin excepción, hemos visto alguna vez en la película de Disney, y/o en remeras, tazas, álbumes de figuritas, cuadernos, y un largo etcétera?

Un dios que se transforma en héroe : Una aproximación genética a los textos de Peter Pan

Desde la perspectiva de la genética textual, en este trabajo observamos las representacionesdel personaje de Peter Pan en los textos de J. M. Barrie dedicados a este con respecto a sussemejanzas con el dios griego Pan, para ver de qué manera dialogan con los diferentes sentidosque el dios fue connotando a través de siglos. Analizamos la fotonovela The Boys Castawaysof Black Lake Island (1901); The Little White Bird (1902), novela en la que aparece en seiscapítulos; las "Fairy Notes" (1903) en borrador y el libreto inédito llamado Anon: a play de la obra teatral Peter Pan or The Boy Who Would Not Grow Up (estrenada en 1904); la novela Peter Pan in Kensington Gardens (1906), que consiste en esos seis capítulos de The LittleWhite Bird; la novela Peter and Wendy (1911), adaptación de la obra de teatro; un guion cinematográfico,Scenario for a Proposed Film of Peter Pan (c. 1918), que no se filmó; y ellibreto de la obra, finalmente publicado, con bastantes cambios, en 1928

Qué Peter Pan conocemos y cómo : Recorridos de un fenómeno intermedial desde su origen

En estas páginas haremos un rastreo de los orígenes, los cambios y las mutaciones del personaje y su historia hasta el modo en que lo conocimos y lo adoptamos como universal y nuestro a través de numerosos y diversos medios, como el cine, la televisión, el comic, el merchandising (por qué no), y los libros, por supuesto; pero también veremos que este niño que no quiere crecer ya nació volátil, inaprehensible, en la mente de J. M. Barrie, quien lo imaginó literario, teatral, cinematográfico, visual. ¿Quién es Peter Pan? ¿Qué imagen, idea, frase, se nos aparece apenas oímos ese nombre? ¿Será el pequeño bebé desnudo que habita los jardines de Kensington, los recorre montado en una cabra y actúa como orquesta de las hadas con la música de su flauta; o ese que se lleva a los hermanitos Darling a Nunca Jamás? ¿O será ese otro que viste de verde, como si fuera un Robin Hood niño, que todos, sin excepción, hemos visto alguna vez en la película de Disney, y/o en remeras, tazas, álbumes de figuritas, cuadernos, y un largo etcétera?

Imitation recognition in a captive chimpanzee (pan troglodytes)

This study investigated the ability of a captive chimpanzee (Pan troglodytes) to recognise when he is being imitated. In the experimental condition of test 1a, an experimenter imitated the postures and behaviours of the chimpanzee as they were being displayed. In three control conditions the same experimenter exhibited (1) actions that were contingent on, but different from, the actions of the chimpanzee, (2) actions that were not contingent on, and different from, the actions of the chimpanzee, or (3) no action at all. The chimpanzee showed more "testing" sequences (i.e., systematically varying his actions while oriented to the imitating experimenter) and more repetitive behaviour when lie was being imitated, than when he was not. This finding was replicated 4 months later in test 1b. When the experimenter repeated the same actions she displayed in the experimental condition of test 1a back to the chimpanzee in test 2, these actions now did not elicit those same testing sequences or repetitive behaviours. However, a live imitation condition did. Together these results provide the first evidence of imitation recognition in a nonhuman animal.

Do chimpanzees (Pan troglodytes) understand single invisible displacement?

Previous research suggests that chimpanzees understand single invisible displacement. However, this Piagetian task may be solvable through the use of simple search strategies rather than through mentally representing the past trajectory of an object. Four control conditions were thus administered to two chimpanzees in order to separate associative search strategies from performance based on mental representation. Strategies involving experimenter cue-use, search at the last or first box visited by the displacement device, and search at boxes adjacent to the displacement device were systematically controlled for. Chimpanzees showed no indications of utilizing these simple strategies, suggesting that their capacity to mentally represent single invisible displacements is comparable to that of 18-24-month-old children.

Do chimpanzees (Pan troglodytes) and 2-year-old children (Homo sapiens) understand double invisible displacement?

Chimpanzees (Pan troglodytes) and young children (Homo sapiens) have difficulty with double invisible displacements in which an object is hidden in two nonadjacent boxes in a linear array. Experiment 1 eliminated the possibility that chimpanzees' previous poor performance was due to the hiding direction of the displacement device. As in Call (2001), subjects failed double nonadjacent displacements, showing a tendency to select adjacent boxes. In Experiments 2 and 3, chimpanzees and 24-month-old children were tested on a new adaptation of the task in which four hiding boxes were presented in a diamond-shaped array on a vertical plane. Both species performed above chance on double invisible displacements using this format, suggesting that previous poor performance was due to a response bias or inhibition problem rather than a fundamental limitation in representational capacity.

Different routes to pure food allergens: extraction, recombinant techniques and total chemical synthesis for obtaining the plant-food pan-allergen LTP

La richiesta di allergeni puri è in continuo aumento per scopi diagnostici, come standard per metodi di rilevamento e di quantificazione, per l'immunoterapia e per lo studio a livello molecolare dei meccanismi delle reazioni allergiche, al fine di facilitare lo sviluppo di possibili cure. In questa tesi di dottorato sono descritte diverse strategie per l’ottenimento di forme pure di non-specific Lipid Transfer Proteins (nsLTPs), le quali sono state riconosciute essere rilevanti allergeni alimentari in molti frutti e verdure comunemente consumati e sono state definite come modello di veri allergeni alimentari. Una LTP potenzialmente allergenica, non nota in precedenza, è stata isolata dalle mandorle, mentre una LTP dall’allergenicità nota contenuta nelle noci è stata prodotta mediante tecniche di DNA ricombinante. Oltre a questi approcci classici, metodi per la sintesi chimica totale di proteine sono stati applicati per la prima volta alla produzione di un allergene, utilizzando Pru p 3, la LTP prototipica e principale allergene della pesca nell'area mediterranea, come modello. La sintesi chimica totale di proteinepermette di controllarne completamente la sequenza e di studiare la loro funzione a livello atomico. La sua applicazione alla produzione di allergeni costituisce perciò un importante passo avanti nel campo della ricerca sulle allergie alimentari. La proteina Pru p 3 è stata prodotta nella sua intera lunghezza e sono necessari solo due passaggi finali di deprotezione per ottenere il target nella sua forma nativa. Le condizioni sperimentali per tali deprotezioni sono state messe a punto durante la produzione dei peptidi sPru p 3 (1-37) e sPru p 3 (38-91), componenti insieme l'intera proteina. Tecniche avanzate di spettrometria di massa sono state usate per caratterizzare tutti i composti ottenuti, mentre la loro allergenicità è stata studiata attraverso test immunologici o approcci in silico.

Representation in the first African World Cup:'world-class', Pan-Africanism, and exclusion

This paper explores the representation of the first African World Cup in the British and South African press. Drawing on the output of a variety of media outlets between 2004, when South Africa was awarded the right to host the 2010 event, and the culmination of the tournament in July 2010, this paper contends that a range of representations of Africa have been put forward by the British and South African media. These can be interpreted as alarmist, sensationalist and even racist in certain extreme instances, and hypernationalist and overly defensive in other cases. © 2012 Copyright Taylor and Francis Group, LLC.

Professionalism and quality in European business courses:utilising research to enhance student learning and promote employability - a pan-European study

This..paper provides a comparative analysis of Quality Management and standards in four European countries, (the UK, Austria, Slovenia and Romania) and in doing so addresses the gap in academic knowledge about how the introduction and implementation of Quality Management Strategies can both facilitate and enhance student learning within Universities.

Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate

Background: We and others have identified the aldo-keto reductase AKR1C3 as a potential drug target in prostate cancer, breast cancer and leukaemia. As a consequence, significant effort is being invested in the development of AKR1C3-selective inhibitors. Methods: We report the screening of an in-house drug library to identify known drugs that selectively inhibit AKR1C3 over the closely related isoforms AKR1C1, 1C2 and 1C4. This screen initially identified tetracycline as a potential AKR1C3-selective inhibitor. However, mass spectrometry and nuclear magnetic resonance studies identified that the active agent was a novel breakdown product (4-methyl(de-dimethylamine)-tetracycline (4-MDDT)). Results: We demonstrate that, although 4-MDDT enters AML cells and inhibits their AKR1C3 activity, it does not recapitulate the anti-leukaemic actions of the pan-AKR1C inhibitor medroxyprogesterone acetate (MPA). Screens of the NCI diversity set and an independently curated small-molecule library identified several additional AKR1C3-selective inhibitors, none of which had the expected anti-leukaemic activity. However, a pan AKR1C, also identified in the NCI diversity set faithfully recapitulated the actions of MPA. Conclusions: In summary, we have identified a novel tetracycline-derived product that provides an excellent lead structure with proven drug-like qualities for the development of AKR1C3 inhibitors. However, our findings suggest that, at least in leukaemia, selective inhibition of AKR1C3 is insufficient to elicit an anticancer effect and that multiple AKR1C inhibition may be required. © 2014 Cancer Research UK. All rights reserved.

Selection of conserved epitopes from hepatitis C virus for pan-populational stimulation of T-cell responses

The hepatitis C virus (HCV) is able to persist as a chronic infection, which can lead to cirrhosis and liver cancer. There is evidence that clearance of HCV is linked to strong responses by CD8 cytotoxic T lymphocytes (CTLs), suggesting that eliciting CTL responses against HCV through an epitope-based vaccine could prove an effective means of immunization. However, HCV genomic plasticity as well as the polymorphisms of HLA I molecules restricting CD8 T-cell responses challenges the selection of epitopes for a widely protective vaccine. Here, we devised an approach to overcome these limitations. From available databases, we first collected a set of 245 HCV-specific CD8 T-cell epitopes, all known to be targeted in the course of a natural infection in humans. After a sequence variability analysis, we next identified 17 highly invariant epitopes. Subsequently, we predicted the epitope HLA I binding profiles that determine their potential presentation and recognition. Finally, using the relevant HLA I-genetic frequencies, we identified various epitope subsets encompassing 6 conserved HCV-specific CTL epitopes each predicted to elicit an effective T-cell response in any individual regardless of their HLA I background. We implemented this epitope selection approach for free public use at the EPISOPT web server. © 2013 Magdalena Molero-Abraham et al.

The migration crisis: representation of a border conflict in Hungarian, German and Pan-European television new coverage

In this article we review the methods used by television news channels in their reporting of the clashes between the Hungarian police and refugees at the Serbian-Hungarian border on 16th of September 2015. With the help of content analysis we examine the techniques used by each editorial board to portray events differently,resulting in dissimilar effects on recipients. During the analysis we examine news coverage for one specific day as presented by Hungarian, German and pan-European broadcasters. German news programs were chosen for comparison with Hungarian ones due to the fact that most of the refugees were heading towards Germany. We conclude that there are significant differences between the information that was broadcast according to television channels; owner expectations presumably play an important role in this.

Remembering Pedro Pan: Faith, Family, and Freedom in Cuban-American Collective Memory , Lecture by Anita Casavantes Bradford

This flyer promotes the event "Remembering Pedro Pan: Faith, Family, and Freedom in Cuban-American Collective Memory Lecture by Anita Casavantes Bradford" and cosponsored by the Latin American and Caribbean Center and the Green Library